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Peter Skellern

Enlightened
Jan 10, 2025
1,068
Would it help adding in Ondansetron along with the Metoclopramide with SN to stop the vomiting, or does it no make a difference?
 
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B

be or not to be

Student
Oct 21, 2024
122
Have you already abandoned opioid method?
 
P

Peter Skellern

Enlightened
Jan 10, 2025
1,068
Last edited:
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Eudaimonic

Eudaimonic

I want to fade away.
Aug 11, 2023
983
The benefit has not been established, but it might help somewhat. Personally, I will use both. No reason no to.
 
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goingoutinstyle

goingoutinstyle

Member
Jul 29, 2021
20
Ondansetron targets serotonin receptors and meto targets dopamine receptors, so I'd like to think combining the two of them would at least be slightly more effective.
 
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platypus77

platypus77

Experienced
Dec 11, 2024
277
If I remember correctly @athiestjoe included both in his protocol.

I tested taking both at the same time and felt nothing different. So I think it doesn't hurt.

The guide he followed:

His GTB:

Documented attempt (successful):
 
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SchrodingerIsDed

SchrodingerIsDed

Arcanist
Feb 17, 2025
415
One additional factor is that if you use the ondansetron sublingually, you might be able to control nausea and vomiting from the serotonin pathway while also not adding volume to the stomach from additional medication.

Seems like it's a no-risk thing to take on top, to me.
 
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