I have no real life friends. I have a few 'friends' on FB that I knew in high school, but nobody ever calls me or texts or anything, even when I've reached out first and attempted to start conversations. I've had poor health and been very isolated for over 20 years now, haven't worked, barely ever go anywhere except to doctor appointments. NObody wants to be friends with a person who is unable to get together and do things and hasn't much to talk about (actually, I do think I have a lot to talk about as I love music and movies and I'm interested in many different things. But everyone my age, and for the last decades, have careers and families and they go on vacations and everything...I've none of those things so, to them anyway, I have nothing to talk about.)
When I was younger I always found it hard to make friends because of my social awkwardness and anxiety, so I'd usually only have one good friend at a time and that's it, with a few casual friends I'd hear from once in awhile. But after my health got bad, even the casual friends drifted away. Sometimes they'll email me but it's only to brag about whatever's happening in their life at the time, and then they disappear again. They never ask me about what's going on with me, or remember anything about my life.
The loneliness and isolation has gotten even worse for me after my mom died 5 years ago because now nobody ever calls or gets in touch, not even my own sister.