Method Enoxaparin OD

[busybee]

OD of Enoxaparin
I stumbled over some ctb (failed) case reports and in case anyone send home with injections wonders if an OD would work:

High chance of survival, takes long, sounds rather painful, unconciousness doesn't seem common, very treatable, the OD and the antidote have long lasting negative side effects, can be treated 'sucessfully' even hours later

It works generally in up to 2 hours in the recommended dose.

Symptoms of an overdose of this drug can include:

• abdominal pain
• black or tarry stool
• nosebleeds
• bleeding gums
• coughing up blood
• bloody vomit

The antidote has 60% efficacy and they have treated it before without the needed lab equipment. Side effects of both the OD and the antidote are common.

Sources for further reading:

Massive intentional enoxaparin overdose managed with minimal protamine: A single case report

AbstractPurpose. The case of a patient with a massive acute enoxaparin overdose managed with observation and minimal doses of protamine sulfate is reported.Summ

academic.oup.com

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541278/

Management of Large Intentional Overdose of Enoxaparin with Protamine Sulfate

Abstract. Abstract 4330Introduction:. Enoxaparin, a low molecular weight heparin (LMWH), is used for prophylaxis and treatment of venous and arterial thromboemb

ashpublications.org

Enoxaparin: Side Effects, Dosage, Uses, and More

Enoxaparin (Lovenox) is an injectable drug used to prevent and treat blood clots. Learn about side effects, warnings, dosage, and more.

www.healthline.com

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900780/#:~:text=Bleeding%20in%20low%2Dmolecular%2Dweight,prevent%20bleeding%20from%20LMWH%20overdose.

Enoxaparin sodium overdose - Reactions Weekly

link.springer.com

 

[CYP11B1]

Why just overdose, instead of using it to ensure you'll bleed out fatally from a cut?

 

[busybee]

Why just overdose, instead of using it to ensure you'll bleed out fatally from a cut?

I just stumbled over reports of people committing with that and wanted to have it documented here so others know that this isn't going to work most likely.

Tbf for methods like jumping or train this could raise mortality from internal/brain bleeding too so as long as it has no cross reaction with other meds that might help

Also there are studies that patients that take 2 highly effective blood thinners have a reduce in migraines (or less pain during attacks). So if someone were to take a bloodthinning painkiller for their method adding this might help negate headaches from constricting brain blood vessels a bit in theory (since that is one of the suspected causes of migraines among other things) but that would be highly expetimental and might really backfire too.