L
LittleJem
Visionary
- Jul 3, 2019
- 2,882
I'm putting this here, as even if I am referred for this therapy (which is unlikely), not everyone responds to it. It is 8 out of 18.
I know that I get blamed for my depression, I also see it myself as laziness. I hate not being able to tidy up. To do my shopping. To dress myself. To have a conversation. To function without drugs. It is not laziness. It is an illness and a curse. It's just one that other people blame you for because they don't understand depression. This paper understands depression.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4185009/ -- it's a research paper on intranasal ketamine. I keep feeling like people want to blame me for my depression, that I'm not 'thinking positive', 'trying hard enough' etc
Major depressive disorder (MDD) is common and a leading worldwide cause of disability (1). Treatment-resistant depression (TRD), characterized by non-response to at least one antidepressant, is associated with a high degree of morbidity and functional disability, and is estimated to occur in up to one third of patients with MDD (2). Even for patients who do respond to standard antidepressant treatments, there is a significant delay in the onset of therapeutic benefit, which further increases illness burden and risks of associated morbidity and suicidality (3). Although neuroscience research has elucidated some of the basic mechanisms of depression and antidepressant action (4), current antidepressant drugs primarily target the monoaminergic system identified decades ago. More recently, the glutamate system has emerged as a critical focus of novel therapeutic development for MDD and particularly TRD (5, 6).
I know the right decision for me is to CTB and yet I still procrastinate the decision.
I get blamed too for using drugs, when I can't get out of bed without them. I can't walk down the street without them. I don't want to be on drugs. I don't want to be mad.
Then it clearly isn't laziness, when a medication or drug kicks in, and suddenly I can clean my room, walk down the street, dress myself and shower. Then, the medication or drug stops working on me, and I am left a vegetable with suicidal thoughts. I don't know what to do.
If I had IV ketamine, I bet it's really unpleasant. But I would be lucky if they tried it on me.
I know that I get blamed for my depression, I also see it myself as laziness. I hate not being able to tidy up. To do my shopping. To dress myself. To have a conversation. To function without drugs. It is not laziness. It is an illness and a curse. It's just one that other people blame you for because they don't understand depression. This paper understands depression.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4185009/ -- it's a research paper on intranasal ketamine. I keep feeling like people want to blame me for my depression, that I'm not 'thinking positive', 'trying hard enough' etc
Major depressive disorder (MDD) is common and a leading worldwide cause of disability (1). Treatment-resistant depression (TRD), characterized by non-response to at least one antidepressant, is associated with a high degree of morbidity and functional disability, and is estimated to occur in up to one third of patients with MDD (2). Even for patients who do respond to standard antidepressant treatments, there is a significant delay in the onset of therapeutic benefit, which further increases illness burden and risks of associated morbidity and suicidality (3). Although neuroscience research has elucidated some of the basic mechanisms of depression and antidepressant action (4), current antidepressant drugs primarily target the monoaminergic system identified decades ago. More recently, the glutamate system has emerged as a critical focus of novel therapeutic development for MDD and particularly TRD (5, 6).
I know the right decision for me is to CTB and yet I still procrastinate the decision.
I get blamed too for using drugs, when I can't get out of bed without them. I can't walk down the street without them. I don't want to be on drugs. I don't want to be mad.
Then it clearly isn't laziness, when a medication or drug kicks in, and suddenly I can clean my room, walk down the street, dress myself and shower. Then, the medication or drug stops working on me, and I am left a vegetable with suicidal thoughts. I don't know what to do.
If I had IV ketamine, I bet it's really unpleasant. But I would be lucky if they tried it on me.