M
myopybyproxy
flickerbeat \\ gibberish-noise
- Dec 18, 2021
- 864
Keeping track of my last four weeks in this thread. If all goes according to plan, by this time next month I shall have been dead for 5 hours.
I will fast for 7 days and/or compile some of my more poetic ravings into a document. At the end of that period, I will do a trial run. One week after that, I will begin my protocol - daily dosing of valerian 400mg, green tea, and grapefruit juice - to inhibit CYP3A4 as much as possible. The goal with this is to limit my body's ability to process substances through that enzymatic 'port', so to speak. I am already an intermediate metaboliser in CYP2D6 so this means that the drugs (opioids are primarily metabolised through CYP2D6 and CYP3A4) will have a longer and hopefully more intense peak.
In the study that supported valerian inhibition of CYP3A4 the researchers used much larger doses, but this is all I have. Tried to make quinine (CYP2D6 inhibitor and lowers QT interval) syrup with cooking grapefruit skins, but I left the fire on too long and it burnt. My natural inhibition should suffice there - most drugs that CYP2D6 metabolises do not affect me much, if at all, or their effect is unexpected. Furthermore, in the week prior to T+0, I will avoid vitamin D and be sure to eat, as both starvation and vitamin D induce CYP3A4. Thus the fast must be done now or sooner, but now is as soon as I could get without travelling backward in time.
My to do list thus includes, aside from the trial run, purchase grapefruits and juice them, keeping up appearances at school, work, and around family (ongoing). Still compiling the writing and practising shooting up (27g and soon to be 25g). On my last day, I will eat a meal and take pills designed to optimise absorption for those drugs that are lipophilic and reduce excretion via pH, send a delayed email containing the document to two musician acquaintances and my brother (drummer in several bands), destroy the hard drive on my laptop, factory reset my phone and destroy the SIM card (idk how it is called), and bike to my location, whereupon I will continue the protocol, which can be read here (the OP is rough draft - updates posted later in the thread - but mostly accurate) if you are curious. At T+0 I will IV 3g of fentanyl positive powder (note NOT 3g of pure fentanyl, unfortunately) and jump / pass out / fall approximately 20m off a bridge into a river. If the overdose does not kill me itself via CNS-depression-induced hypoxia, I will be too out of it to swim. The 40lb weights should insure I stay submerged. If I'm still breathing by the time I hit the water, suffocation (mechanism of drowning) will allow my spirit to inhabit another body.
Without raising suspicion, I will also look into the train schedules. Wouldn't want a passenger or railway employee interfering.
My only concern is storage of one of the sedatives - I kept it in a shot glass due to attempting to create an emulsion (yes, yes, not the same as a solution, facepalms into infinity). I will update on that.
If you have any questions or comments as to the practical details, please feel free to share. I certainly have not thought of everything and it is best to consider and control for as many factors as possible. Or any questions at all, I'm bored and lonely lmao.
I will fast for 7 days and/or compile some of my more poetic ravings into a document. At the end of that period, I will do a trial run. One week after that, I will begin my protocol - daily dosing of valerian 400mg, green tea, and grapefruit juice - to inhibit CYP3A4 as much as possible. The goal with this is to limit my body's ability to process substances through that enzymatic 'port', so to speak. I am already an intermediate metaboliser in CYP2D6 so this means that the drugs (opioids are primarily metabolised through CYP2D6 and CYP3A4) will have a longer and hopefully more intense peak.
In the study that supported valerian inhibition of CYP3A4 the researchers used much larger doses, but this is all I have. Tried to make quinine (CYP2D6 inhibitor and lowers QT interval) syrup with cooking grapefruit skins, but I left the fire on too long and it burnt. My natural inhibition should suffice there - most drugs that CYP2D6 metabolises do not affect me much, if at all, or their effect is unexpected. Furthermore, in the week prior to T+0, I will avoid vitamin D and be sure to eat, as both starvation and vitamin D induce CYP3A4. Thus the fast must be done now or sooner, but now is as soon as I could get without travelling backward in time.
My to do list thus includes, aside from the trial run, purchase grapefruits and juice them, keeping up appearances at school, work, and around family (ongoing). Still compiling the writing and practising shooting up (27g and soon to be 25g). On my last day, I will eat a meal and take pills designed to optimise absorption for those drugs that are lipophilic and reduce excretion via pH, send a delayed email containing the document to two musician acquaintances and my brother (drummer in several bands), destroy the hard drive on my laptop, factory reset my phone and destroy the SIM card (idk how it is called), and bike to my location, whereupon I will continue the protocol, which can be read here (the OP is rough draft - updates posted later in the thread - but mostly accurate) if you are curious. At T+0 I will IV 3g of fentanyl positive powder (note NOT 3g of pure fentanyl, unfortunately) and jump / pass out / fall approximately 20m off a bridge into a river. If the overdose does not kill me itself via CNS-depression-induced hypoxia, I will be too out of it to swim. The 40lb weights should insure I stay submerged. If I'm still breathing by the time I hit the water, suffocation (mechanism of drowning) will allow my spirit to inhabit another body.
Without raising suspicion, I will also look into the train schedules. Wouldn't want a passenger or railway employee interfering.
My only concern is storage of one of the sedatives - I kept it in a shot glass due to attempting to create an emulsion (yes, yes, not the same as a solution, facepalms into infinity). I will update on that.
If you have any questions or comments as to the practical details, please feel free to share. I certainly have not thought of everything and it is best to consider and control for as many factors as possible. Or any questions at all, I'm bored and lonely lmao.