A couple things. 4500 cu ft is quite a lot of volume. With a small generator, it would be difficult, if not impossible, at least in my opinion, to achieve a desireably high enough CO level that would allow one to ctb in a "comfortable" fashion. The other thing is that newer, modern generators have catalytic converters, similar to vehicles, that substantially limit the amount of CO and other pollutants that get emitted. Many even have a safety feature that shuts them down when a minimal CO threshold amount is detected. Generators are best for small spaces and, even then, you'd have to modify the generator by removing the catalytic converter. Older ones can work, but again, they'd be best used in a small volume of space. And, of course, you'd be subject to breathing all of the other noxious gases emitted as by-products of the internal combustion process.