Method 1,4 butanediol megathread

[About_to_Go]

Just checked into a hotel. Planning to ctb with 2 oz (60ml) of 1,4 Butanediol tonight

 

[Retched]

Just checked into a hotel. Planning to ctb with 2 oz (60ml) of 1,4 Butanediol tonight

Peaceful travels.

 

[About_to_Go]

Thank you @Retched. What do you folks think I should take for meto? I was thinking 30mg before

 

[Retched]

Thank you @Retched. What do you folks think I should take for meto? I was thinking 30mg before

I'm not sure with the meto... that dose sounds legit though. I'm uninformed maybe post on new thread so people can chime in?

 

[RememberWhatUCameFor]

I've been looking at news articles where people have died "accidentally" from it, usually mixed with alcohol and trying to interpret a potentially reliable method from that. But the most recent Manchester Evening News article (also posted earlier on in the thread) makes it out to be very easy, I feel it was intentional and wonder what her dose was before she drank this supposed single glass of prosecco. But it also mentions that in the past, she had downed 50ml of the stuff and ended up in a coma in ICU, this time she was found hours later and was dead. There have been a few stories like this though when questioning this, the newspapers only like to report the really gory, juicy cases. Even scientific papers aren't reliable, for the same LD50 etc. Reason. It's just trial and error most of the time until there have been enough documented trials and errors! I will be giving this a go and when I do, I'll try to post as much as I can on here.

https://www.who.int/medicines/areas/quality_safety/4.1GHBcritical_review.pdf

 

[RememberWhatUCameFor]

Thank you @Retched. What do you folks think I should take for meto? I was thinking 30mg before

still not sure if not a lot of the death result from choking on your vomit while being passed out

 

[MistakesHappen]

Just checked into a hotel. Planning to ctb with 2 oz (60ml) of 1,4 Butanediol tonight

Good luck Mate, wish you the best.

 

[About_to_Go]

Just drank it with come and rum. It tastes like cough medicine but it's not bad

 

[About_to_Go]

Bitter

 

[Toenditall]

Just drank it with come and rum. It tastes like cough medicine but it's not bad

hope you find your peace

 

[onegoodreason]

Blessings, Love and Peace to you, Dearheart! May the Light envelope you and guide you safely Home. Peace.

 

[Ashpac]

https://www.erowid.org/chemicals/14b/14b.shtml

Hope this helps.

I used this site all the time in 2003 back in my drug days so i knew all the risks and effects of chemicals.

 

[Made4TV]

The addendum at the bottom of this report is interesting - suggesting mixing with grapefruit juice: https://www.erowid.org/experiences/exp.php?ID=29274

 

[RememberWhatUCameFor]

The addendum at the bottom of this report is interesting - suggesting mixing with grapefruit juice: https://www.erowid.org/experiences/exp.php?ID=29274

yes grapefruit seems to enhance the effect of a lor of medication and drugs


unfortunately it tastes like shit too

 

[onegoodreason]

Just found this and thought I'd share. It's a couple of excerpts from an Australian site, but the following is general info. Hope this helps us in some way.
*****************
Health and safety information
The major source of the information about health effects is a report prepared under the Organisation for Economic Co-operation and Development (OECD) Screening Information Data Set (SIDS) Program.

The SIDS Initial Assessment Report (SIAR) on 1,4-butanediol, finalised in 2000, was the primary reference source. A comprehensive literature search was carried out for data published since 1999 to ensure that those studies published after the last literature search conducted for the SIAR were also reviewed and summarised in the NICNAS report.

After oral or intravenous administration, 1,4-butanediol is rapidly and efficiently metabolised in the liver to form GHB. In humans, extensive conversion of 1,4-butanediol to GHB after oral dosing indicated that ingestion of 1,4-butanediol is essentially equivalent to GHB intake. Peak blood levels are achieved after 30 to 60 minutes.

No data are available on dermal absorption.
----

Human data
Acute toxicity
The critical toxic effect of 1,4-butanediol is neurotoxicity. Central nervous system disturbances including decreased alertness, dizziness and respiratory depression have been reported following oral dosing at 25 mg/kg bw. More significant effects occur at higher doses and by other routes of administration with sleep induction, restlessness and myoclonus (a quick, involuntary twitching of a muscle or muscle group) reported to occur following intravenous administration of 30 mg/kg bw and miosis (constriction of the pupil of the eye), areflexia (absence of reflexes), coma and death observed in patients after rectal administration of 15 or 30g 1,4-butanediol (estimated at 200 or 400 mg/kg bw).

Experience with human exposure—case studies
Numerous case reports are available that describe the neurological consequences (including agitation, combativeness, respiratory depression, a labile (imbalanced or unbalanced) level of consciousness, vomiting, seizures and death) in patients known to have ingested illicit products containing 1,4-butanediol.

The inability to accurately determine the dose of 1,4-butanediol ingested—and the co-exposure to other chemicals present at unreported concentration in these products in many cases—means that it is not possible to correlate the degree of 1,4-butanediol exposure with the severity of neurotoxicity from these reports.

In late 2007 in Australia, four children were hospitalised after swallowing 'Bindeez' brand toy beads that were found to be coated with 1,4-butanediol, however quantification of the amount of 1,4-butanediol ingested was not reported.

International regulatory activities
USA
In May 1999, the USA Food and Drug Administration (FDA) issued a public warning about products containing 1,4 butanediol and declared the chemical to be a Class I Health Hazard (i.e. potentially life-threatening).

Although this classification imposes no legal restrictions on the manufacture, distribution or possession of 1,4 butanediol, when 1,4 butanediol is distributed for human consumption it meets the definition of a 'controlled substance analogue' and distributors can therefore be prosecuted for supplying a Schedule 1 substance.

New Zealand
The chemical has been classified as Class B1 (i.e. a drug posing a high risk of harm) under the Misuse of Drugs Act 1975.

Other
The chemical is not subject to the key United Nations (UN) Convention that covers precursor chemicals; however its metabolite, GHB, is subject to international controls in accordance with the 1971 UN convention on psychotropic substances.

Please note, our recommendations are not always implemented by chemical regulators. For the most up-to-date information about how a particular chemical is regulated in your State or Territory you will need to contact other government agencies. Read What we do for details about our regulatory partners.

Last update 1 May 2013

Related content

• 
  1,4-Butanediol—hazard assessment [WORD 553 KB]
  
  The major uses of 1,4-butanediol are as an intermediate and chain extender in the production of urethane prepolymers, polyether diols, polyester polymers
  (particularly polybutylene terephthalate) and in the manufacture of tetrahydrofuran

 

[Arak]

@onegoodreason ,

Thanks, that's a very good one.

The LD50 appears to be high, and it depends on rout of administration.

Quote '
Acute oral toxicity

Rat: LD50 1525-1830 mg/kg bw.

Rabbit: LD50 2531 mg/kg bw.'

' Acute human toxicity

Unconsciousness, miosis, areflexia, renal failure and death (210-

430 mg/kg per rectum). Restlessness, clonic spasms of extremity

muscles, sleep (30 mg/kg bw i.v.).'


It does not mention ldlo, ld50 or anything like that. In that sense, animal values may be easier to read.
As a whole, a good read. It confirms my impression that it's not a reliable means of 'ctb'. Things change when you add drugs.

 

[RememberWhatUCameFor]

coma and death observed in patients after rectal administration of 15 or 30g 1,4-butanediol (estimated at 200 or 400 mg/kg bw).

so rectal administration is apparently a thing..at least you dont need antimetics

not sure if it wont burn your rectum though...probably not a good idea

you dont need much though if you do it rectal



1.4b has a density of almost 1 so 1ml = 1g

so a 90kg man would need between...


90*200mg = 18.000mg = 18g = 18ml

90*400mg = 36.000mg = 36g = 36ml


even lower if combined with alcohol



not sure if you need to take more if you do it orally

 

[xenos]

To anyone in the UK who's bought it, which seller do you guys think is reliable? I already have SN but might try this instead when I do my research.

 

[TiredHorse]

so rectal administration is apparently a thing..at least you dont need antimetics

not sure if it wont burn your rectum though...probably not a good idea

you dont need much though if you do it rectal

If I remember correctly from the original thread, before it was deleted, a user did apply a few drops rectally and reported no unpleasant affects. I know nothing of the administration technique, though, so hopefully someone will be along soon and give advice on that. I haven't seen @gingerplum in a couple days, but given her medical background she might be the most reliable source for advice.

 

[Toenditall]

If I remember correctly from the original thread, before it was deleted, a user did apply a few drops rectally and reported no unpleasant affects. I know nothing of the administration technique, though, so hopefully someone will be along soon and give advice on that. I haven't seen @gingerplum in a couple days, but given her medical background she might be the most reliable source for advice.

that was me i tired it no burning at all

 

[journeytotheend]

Found out recently that I have easy access to both GHB and GBL, through illegal but fairly trustworthy local sources. After reading up on the method, I am now more an more considering to use this as my method. But there is one problem, there is no easy way to get a hold of meto in my country, and I see no point in doing this without it. I could order it online, but I don´t want to risk it being seized in customs. Does anyone have suggestions to countries where I could go and get it otc without any hassle? Planning to do some traveling before I ctb anyways.

 

[deathembrace]

Found out recently that I have easy access to both GHB and GBL, through illegal but fairly trustworthy local sources. After reading up on the method, I am now more an more considering to use this as my method. But there is one problem, there is no easy way to get a hold of meto in my country, and I see no point in doing this without it. I could order it online, but I don´t want to risk it being seized in customs. Does anyone have suggestions to countries where I could go and get it otc without any hassle? Planning to do some traveling before I ctb anyways.

Ive ordered meto from greek seller and it hasnt got seized by the customs, if you are from Europe it should come pretty fast aswell

 

[onegoodreason]

OK, I'm a dummy so I need to ask, how much of the 1,4b would I need to take for a lethal dose? I weigh about 110-115. Need conversion from ml to oz, too. Want to know how much to order, if I go this way. Is fasting for any time before hand a good idea? Can it be mixed with alcohol, or is water or juice better? Use alcohol as a before/after chaser OK? Plan to use antiemetics 8 hours before, then another 30 mins. before, but again, not sure of proper dose - help with that, too, please. Sound good? Thank you, my friends! :-)

 

[RememberWhatUCameFor]

Found out recently that I have easy access to both GHB and GBL, through illegal but fairly trustworthy local sources. After reading up on the method, I am now more an more considering to use this as my method. But there is one problem, there is no easy way to get a hold of meto in my country, and I see no point in doing this without it. I could order it online, but I don´t want to risk it being seized in customs. Does anyone have suggestions to countries where I could go and get it otc without any hassle? Planning to do some traveling before I ctb anyways.

coma and death observed in patients after rectal administration of 15 or 30g 1,4-butanediol (estimated at 200 or 400 mg/kg bw).

you dont need meto with rectal administration

 

[RememberWhatUCameFor]

OK, I'm a dummy so I need to ask, how much of the 1,4b would I need to take for a lethal dose? I weigh about 110-115. Need conversion from ml to oz, too. Want to know how much to order, if I go this way. Is fasting for any time before hand a good idea? Can it be mixed with alcohol, or is water or juice better? Use alcohol as a before/after chaser OK? Plan to use antiemetics 8 hours before, then another 30 mins. before, but again, not sure of proper dose - help with that, too, please. Sound good? Thank you, my friends! :-)

coma and death observed in patients after rectal administration of 15 or 30g 1,4-butanediol (estimated at 200 or 400 mg/kg bw).

115 lbs? = 52kg

400mg/kg * 52kg = 20.800mg = 20.8g


1.4b has a density of almost 1 so 1ml = 1g


20.8g = 20.8ml


to be sure consume alcohol too

 

[onegoodreason]

115 lbs? = 52kg

400mg/kg * 52kg = 20.800mg = 20.8g


1.4b has a density of almost 1 so 1ml = 1g


20.8g = 20.8ml


to be sure consume alcohol too

Thank you, RememberWhatUCameFor, I appreciate your response, but could you translate that into English for me, please? I don't understand the metric systems at all. The bottle I may get is 1 oz., how does that translate? Is 1 oz. = to 60ml? How many ounces is 20.8g or 20.8ml?

Hang on, I think I've got a syringe I've never used that was supposed to be for assist feeding my kitties and it goes to 60ml. This thing is big! And it says right on it that 30ml is 1 oz and 60ml is 2 oz!! Cool. So, if 20.8ml would "do it" for me, then I only need a 1 oz bottle, not 2 oz. Would the extra 10ml or so be too much and perhaps induce vomiting? Or would it help to ensure death? Anyone? Just tested the amount with the syringe for 30ml and that would go down in one mouthful and two swallows. Yahoo!

I realize going through the rectum is also another way to administer, but I'm not sure how that would be done, either. Create a suppository out of it, somehow? Squeeze a dropper right in there? Yikes!? Steady hands and good aim required there, all at an awkward angle. Think I'll drink it, antiemetics on board, and Bailey's cherry chocolate before and after!! Yeah. Could I mix the 1,4b right into the alcohol, or better to keep them separated, drinking the alcohol before and after the 1,4b? And death should be fairly swift, barring being found before hand, though that's unlikely in my situation. Husband doesn't come in here unless he has to these days, happily.

Arak, I know you're very skeptical of this method, could you say again why that is? I'm glad you found the excerpts I posted helpful, but I don't understand the technical jargon. Could you translate into understandable English? What is LD50? ldlo? Converting kg to mg to ml?? (roll eyes) I just don't understand this stuff!? I'm leaning more toward this method as it is somewhat easier to acquire and far less expensive than N. And going by what About To Go last posted, looks like he was successful with it, though we don't know for sure yet. How do we find that out, by the way? My intent is to send a final post here, but I will be clearing my computer of as much as I can with relation to this group before I go, so won't be posting a moment to moment "play by play". But I would like you all to know that I succeeded, or not. How would I set that up? Suggestions, please!

Thanks, all. Peace. :-)

 

[Scottishchef]

To anyone in the UK who's bought it, which seller do you guys think is reliable? I already have SN but might try this instead when I do my research.

Hi i just ordered sone of ebay from germany

https://rover.ebay.com/rover/0/0/0?mpre=https://www.ebay.de/ulk/itm/391988283035

 

[Arak]

Starting with a quote: https://psychonautwiki.org/wiki/1,4-Butanediol '
It is converted into GHB in the liver by the enzymes alcohol dehydrogenase and aldehyde dehydrogenase, which is the same enzyme as alcohol.[6] 1,4-Butanediol is first converted into 4-hydroxybutaldehyde in the liver and is released into the bloodstream before returning to the liver to convert into GHB. This process results in a much more delayed onset than GBL or GHB.[7]

The differing levels of dehydrogenase enzymes can vary between individuals, meaning that, like alcohol, effects can differ greatly between users. In many, this manifests as a slow onset of effects and a higher rate of aldehyde collecting in the bloodstream, causing more toxic side effects. Because of these pharmacokinetic differences, 1,4-butanediol tends to be less potent and with a slower onset than GHB but has a longer duration; the related compound GBL tends to be slightly more potent and faster to take effect but more short-acting than GHB. ' Empasis on BOLD. Logical, it needs to be converted. So in a way 1 gr of 1,4 butanediol is not equal to 1 gr of GHB. But skipping that for a moment:

Let's see if I got this right: assuming a weight of 60 kg, one needs a dose of 120 gr to achieve a LD50 value. Extrapolating from animals.
That's not even close to LD100, and not taking into account tolerance for CNS depressants.

A dose of 120 gr or 120 ml (liquid), is that doable (oral consumption) ?

 

[Suicat]

I'm planning on drinking 100ml on an empty stomach, I just hope it works because I'm very overweight and I don't think I'll be able to manage drinking more than 100ml even with meto. I don't know whether to use a shot glass and just shot it back neat then consume something to mask the aftertaste. Or whether to mix it into something but it's a lot more liquid than the suggestions of mixing a few ml to get high. I have benzos at home but I'm uncertain as to whether I'll be able to access them, but I'll get a bottle of something alcoholic in to drink after I've consumed the 1.4BDL. I think it'll get done next week, fingers crossed ...

 

[lukaszz12]

I'm planning on drinking 100ml on an empty stomach, I just hope it works because I'm very overweight and I don't think I'll be able to manage drinking more than 100ml even with meto. I don't know whether to use a shot glass and just shot it back neat then consume something to mask the aftertaste. Or whether to mix it into something but it's a lot more liquid than the suggestions of mixing a few ml to get high. I have benzos at home but I'm uncertain as to whether I'll be able to access them, but I'll get a bottle of something alcoholic in to drink after I've consumed the 1.4BDL. I think it'll get done next week, fingers crossed ...

Hey, please use GBL. It is more potent than 1,4-bd and it has a more bearable taste. I doubt you would be able to down 100ml of 1,4bd it's really something disgusting and vile.