Method Zofran (ondansetron) vs. metoclopramide for oxycodone ctb?

[apict]

I feel like I've read conflicting info here about whether Zofran is a reliable substitute for metoclopramide to prevent vomiting when attempting ctb with oxycodone.
Can anyone help clarify? Also, would cannabis help?
thanks.

 

[LastNite]

Why are you taking it orally?

 

[apict]

As opposed to anally? Just because I've never shoved anything up my butt before and because the amount of water required to dissolve the suggested 400mg oxy seems excessive. Also, I've read that if going anally, that dose should be increased. Don't know by how much, and am now uncertain how much water would be required to dissolve.
Can anyone straighten me out?

 

[OzymandiAsh]

According to the PPH yes, smoking cannabis 20 mins before would help. Not sure about the main question tho.

As opposed to anally? Just because I've never shoved anything up my butt before and because the amount of water required to dissolve the suggested 400mg oxy seems excessive. Also, I've read that if going anally, that dose should be increased. Don't know by how much, and am now uncertain how much water would be required to dissolve.
Can anyone straighten me out?

You didn't even specify orally so I'm not sure why they asked that either lol. Snorting it would actually be more effective though btw. Look into that (use Grok)