• Hey Guest,

    We wanted to share a quick update with the community.

    Our public expense ledger is now live, allowing anyone to see how donations are used to support the ongoing operation of the site.

    👉 View the ledger here

    Over the past year, increased regulatory pressure in multiple regions like UK OFCOM and Australia's eSafety has led to higher operational costs, including infrastructure, security, and the need to work with more specialized service providers to keep the site online and stable.

    If you value the community and would like to help support its continued operation, donations are greatly appreciated. If you wish to donate via Bank Transfer or other options, please open a ticket.

    Donate via cryptocurrency:

    Bitcoin (BTC):
    Ethereum (ETH):
    Monero (XMR):
T

tanaka10

Member
Aug 6, 2024
44
Imagine you could get any medication you wanted, with or without a prescription (which is my case ^^). Which one would you choose for an overdose???
(Just to clarify, I can only get medications available at pharmacies that don't require a secure prescription, e.g., opioids, curare, anesthetics: propofol and thiopental), but I can get everything else.

Which one would you choose?
Here's my list:
- 3 different types of benzos (oxazepam, bromazepam, and diazepam)
- Maximum dose of phenobarbital
- Non-cardioselective beta-blocker: propranolol
- Antiemetics: ondansetron and metoclopramide

Even though this combination is dangerous, it is likely not fatal without opioids or barbiturates.
So what would you do???
Thank you all for your answers
 
  • Love
Reactions: bl33ding_heart
F

Forveleth

I knew I forgot to do something when I was 15...
Mar 26, 2024
4,268
None of these. Medication ODs are extremely unreliable.
 
  • Like
Reactions: Box and Hollowman
if_i_make_it

if_i_make_it

Member
Apr 30, 2026
99
overdose from prescription opioids are very rare. it is street drugs that are dangerous.
but the reason medication OD is considered a non method is because they are generally not lethal and there are too many unknown factors to make it reliable. possible, maybe, but not in a way anyone here or any resource can really help you with.
 
  • Like
Reactions: rainatthebusstop and Forveleth
Littlepaws

Littlepaws

Member
Sep 4, 2021
77
How much Propranolol do you intend to use? At a sufficient quantity, that alone can be fatal.
 
Littlepaws

Littlepaws

Member
Sep 4, 2021
77
more than 5 grams
I've read some medical reports, and some people have used similar amounts. Propranolol is part of my plan, though I intend to take it with amitriptyline
 
T

tanaka10

Member
Aug 6, 2024
44
I've read some medical reports, and some people have used similar amounts. Propranolol is part of my plan, though I intend to take it with amitriptyline
It's true that amitriptyline is listed in the PPHE, but it recommends combining it with a digitalis: digoxin.

However, digitalis overdoses are well known to cause severe vomiting, unlike propranolol.

Personally, I stick with propranolol; even though an overdose of propranolol alone isn't very dangerous, when combined with other antihypertensive medications, there is a real risk of shock.

I think the only way to achieve CTB with medication is to have a combination of benzodiazepines + a cardiotoxic agent (propranolol or amitriptyline + digoxin) and an opioid or propofol or thiopental

but the problem remains the same: accessibility...
 
J

Jrileniwa

Member
May 6, 2026
23
Sorry for the question, but would Triazolam help in case one would want to drown or get through certain demanding ordeals to do the thing?
 
T

tanaka10

Member
Aug 6, 2024
44
Sorry for the question, but would Triazolam help in case one would want to drown or get through certain demanding ordeals to do the thing?
It's a benzodiazepine… It will ease anxiety before the CTB, but not the pain.

I've taken high doses of benzos before; I fell asleep quickly, but I was still able to wake up.

In the event of drowning, it won't relieve the pain.
 
Littlepaws

Littlepaws

Member
Sep 4, 2021
77
It's true that amitriptyline is listed in the PPHE, but it recommends combining it with a digitalis: digoxin.

However, digitalis overdoses are well known to cause severe vomiting, unlike propranolol.

Personally, I stick with propranolol; even though an overdose of propranolol alone isn't very dangerous, when combined with other antihypertensive medications, there is a real risk of shock.

I think the only way to achieve CTB with medication is to have a combination of benzodiazepines + a cardiotoxic agent (propranolol or amitriptyline + digoxin) and an opioid or propofol or thiopental

but the problem remains the same: accessibility...
I've been prescribed Amitriptyline for about 3 years now, but I recently started stockpiling because I noticed they are allowing me to renew my prescription earlier than usual. And then some non-doctor prescriber started me on propranolol, but I don't really use it much... I have started stockpiling because they keep letting me renew my prescription without any question :I
 
T

tanaka10

Member
Aug 6, 2024
44
I've been prescribed Amitriptyline for about 3 years now, but I recently started stockpiling because I noticed they are allowing me to renew my prescription earlier than usual. And then some non-doctor prescriber started me on propranolol, but I don't really use it much... I have started stockpiling because they keep letting me renew my prescription without any question :I
Do you have a lot of them?
 
J

Jrileniwa

Member
May 6, 2026
23
It's a benzodiazepine… It will ease anxiety before the CTB, but not the pain.

I've taken high doses of benzos before; I fell asleep quickly, but I was still able to wake up.

In the event of drowning, it won't relieve the pain.
Ok, thank you. The pain is not what I'm afraid about, it's just the failing part.
 
salviap

salviap

I am no longer interested in the world.
Apr 7, 2024
61
Imagine you could get any medication you wanted, with or without a prescription (which is my case ^^). Which one would you choose for an overdose???
(Just to clarify, I can only get medications available at pharmacies that don't require a secure prescription, e.g., opioids, curare, anesthetics: propofol and thiopental), but I can get everything else.

Which one would you choose?
Here's my list:
- 3 different types of benzos (oxazepam, bromazepam, and diazepam)
- Maximum dose of phenobarbital
- Non-cardioselective beta-blocker: propranolol
- Antiemetics: ondansetron and metoclopramide

Even though this combination is dangerous, it is likely not fatal without opioids or barbiturates.
So what would you do???
Thank you all for your answers
If it were a reliable method, I'd probably choose the medications I currently have access to: Pregabalin (an anticonvulsant/gabapentinoid), Clonidine (an antihypertensive), Xanax (benzodiazepine), and Gabapentin (gabapentinoid). Maybe with the correct (large) amount, these medications could cause severe amounts of respiratory depression, and rarely death, but it would have to be some crazy quantity for it to be fatal. (At least this applies to most OTC and prescription medication, maybe not Xanax, but I'm unsure...) I consider it, but I know it won't work, and it is heavily unreliable..
 
J

Johnny20

Member
May 12, 2026
16
Imagine you could get any medication you wanted, with or without a prescription (which is my case ^^). Which one would you choose for an overdose???
(Just to clarify, I can only get medications available at pharmacies that don't require a secure prescription, e.g., opioids, curare, anesthetics: propofol and thiopental), but I can get everything else.

Which one would you choose?
Here's my list:
- 3 different types of benzos (oxazepam, bromazepam, and diazepam)
- Maximum dose of phenobarbital
- Non-cardioselective beta-blocker: propranolol
- Antiemetics: ondansetron and metoclopramide

Even though this combination is dangerous, it is likely not fatal without opioids or barbiturates.
So what would you do???
Thank you all for your answers
Hi, could you tell me how you manage to get all this? I'm interested.
 
  • Like
Reactions: tanaka10

Similar threads

somelex
Replies
2
Views
417
Suicide Discussion
WhyMe123
W
T
Replies
0
Views
223
Suicide Discussion
tanaka10
T
absolutethistime
Replies
6
Views
2K
Suicide Discussion
Buckley
B
purebliss
Replies
52
Views
3K
Suicide Discussion
EscThisPlace321
E
J
Replies
11
Views
2K
Suicide Discussion
Serena fuga
Serena fuga