Resource SN megathread

[Whatshername]

[

Anyone know where to get SN in Norway?

Apc pure ships worldwide.

 

[Raggas]

I'm having concern over anti-emetics in Australia, I did find an eBay seller however they require pharmacist advice before selling as stated in the full description.

https://www.ebay.com.au/itm/ANAGRAINE-HYDROCHLORIDE-5MG-PARACETAMOL-500MG-8-TABLETS/182547399120

My question is has any Australian bought Anagraine off eBay successfully? Did it require a phone interview with the seller? If so how did you go about it?

 

[Bentham]

is nexium an alternative to tagamet.

Based on PN's argument in PPH, and suppose that there is no material adverse interaction of SN and PPIs including Nexium (Esomeprazole), Nexium should be an alternative to Tagamet.
PN's argument now is that gastric fluid volume is important and gastric pH is irrelevant. But he gave no explanation on why and he previously recommended sodium bicarbonate, which increase gastric pH.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2036.2009.04128.x
"Proton pump inhibitors (PPI) are the most effective antisecretory drugs for controlling gastric acidity. They inhibit both basal and stimulated secretion of gastric acid, independent of the nature of the parietal cell stimulation. The inhibition of gastric acidity has been demonstrated in many studies in healthy volunteers and patients with gastro-oesophageal reflux disease (GERD), but the effect of PPI on gastric volume secretion has been poorly investigated. To date, studies which compare the effect of PPI with placebo, other PPI, or H2 receptor antagonists on gastric volume have been performed after induction of general anaesthesia for elective surgery. Their main conclusion is that these two classes of antisecretory medication exert a favourable effect by decreasing gastric fluid secretion."

The article above is about an Esomeprazole IV case study but as a whole, including citation 8 - 13, I think it is helpful for you to decide whether you choose, as well as how much you take, Nexium as an absorption accelerator. Interchangeability among PPIs is here. I can not find any direct interchange chart of D2 blockers and PPIs.

However, some 8ch user(s) argue(s), based on several journals including the one below, that PPIs should be avoided because PPIs increase gastric pH and blunt the acute hypotension effect, which leads to swift unconsciousness.
https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.116.08081
"the present study suggests that the acute blood pressure–lowering effect of oral nitrite is dependent on an acidic gastric environment."

Some journals as I mentioned here show that D2 blockers such as cimetidine also increase gastric pH.

 

[Syn1991]

Based on PN's argument in PPH, and suppose that there is no material adverse interaction of SN and PPIs including Nexium (Esomeprazole), Nexium should be an alternative to Tagamet.
PN's argument now is that gastric fluid volume is important and gastric pH is irrelevant. But he gave no explanation on why and he previously recommended sodium bicarbonate, which increase gastric pH.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2036.2009.04128.x
"Proton pump inhibitors (PPI) are the most effective antisecretory drugs for controlling gastric acidity. They inhibit both basal and stimulated secretion of gastric acid, independent of the nature of the parietal cell stimulation. The inhibition of gastric acidity has been demonstrated in many studies in healthy volunteers and patients with gastro-oesophageal reflux disease (GERD), but the effect of PPI on gastric volume secretion has been poorly investigated. To date, studies which compare the effect of PPI with placebo, other PPI, or H2 receptor antagonists on gastric volume have been performed after induction of general anaesthesia for elective surgery. Their main conclusion is that these two classes of antisecretory medication exert a favourable effect by decreasing gastric fluid secretion."

The article above is about an Esomeprazole IV case study but as a whole, including citation 8 - 13, I think it is helpful for you to decide whether you choose, as well as how much you take, Nexium as an absorption accelerator. Interchangeability among PPIs is here. I can not find any direct interchange chart of D2 blockers and PPIs.

However, some 8ch user(s) argue(s), based on several journals including the one below, that PPIs should be avoided because PPIs increase gastric pH and blunt the acute hypotension effect, which leads to swift unconsciousness.
https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.116.08081
"the present study suggests that the acute blood pressure–lowering effect of oral nitrite is dependent on an acidic gastric environment."

Some journals as I mentioned here show that D2 blockers such as cimetidine also increase gastric pH.

Dont use sodium bicarbonate it does protects you against sodium nitrite poisoning https://www.ncbi.nlm.nih.gov/m/pubmed/7974833/

 

[Done182]

Hi I have a question about timing, Is it stat dose or ahead regime?

 

[drakewantstogo]

Hi I have a question about timing, Is it stat dose or ahead regime?

What is the question?

 

[Done182]

What order do you take the acid regulator, anti vomit pills and SN and what are the time intervals?

 

[NoOneKnows]

Based on PN's argument in PPH, and suppose that there is no material adverse interaction of SN and PPIs including Nexium (Esomeprazole), Nexium should be an alternative to Tagamet.
PN's argument now is that gastric fluid volume is important and gastric pH is irrelevant. But he gave no explanation on why and he previously recommended sodium bicarbonate, which increase gastric pH.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2036.2009.04128.x
"Proton pump inhibitors (PPI) are the most effective antisecretory drugs for controlling gastric acidity. They inhibit both basal and stimulated secretion of gastric acid, independent of the nature of the parietal cell stimulation. The inhibition of gastric acidity has been demonstrated in many studies in healthy volunteers and patients with gastro-oesophageal reflux disease (GERD), but the effect of PPI on gastric volume secretion has been poorly investigated. To date, studies which compare the effect of PPI with placebo, other PPI, or H2 receptor antagonists on gastric volume have been performed after induction of general anaesthesia for elective surgery. Their main conclusion is that these two classes of antisecretory medication exert a favourable effect by decreasing gastric fluid secretion."

The article above is about an Esomeprazole IV case study but as a whole, including citation 8 - 13, I think it is helpful for you to decide whether you choose, as well as how much you take, Nexium as an absorption accelerator. Interchangeability among PPIs is here. I can not find any direct interchange chart of D2 blockers and PPIs.

However, some 8ch user(s) argue(s), based on several journals including the one below, that PPIs should be avoided because PPIs increase gastric pH and blunt the acute hypotension effect, which leads to swift unconsciousness.
https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.116.08081
"the present study suggests that the acute blood pressure–lowering effect of oral nitrite is dependent on an acidic gastric environment."

Some journals as I mentioned here show that D2 blockers such as cimetidine also increase gastric pH.

However, some 8ch user(s) argue(s), based on several journals including the one below, that PPIs should be avoided because PPIs increase gastric pH -
How can a PPI increase gastric PH and at the same time inhibit gastric acidity ?
That makes no sense, when there is a medication that can only be absorbed with acidic stomach, they clearly state dont take PPI or any anti acid medication 24 hours prior . I dont understand why PPeH makes Zantac as a preferred option to PPI

 

[Done182]

What is the question?

What is the question?

What order do you take the acid regulator, anti vomit pills and SN and what are the time intervals?
Hope I phrased that okay

 

[Bentham]

How can a PPI increase gastric PH and at the same time inhibit gastric acidity ?

Higher pH is less acidic.
https://simple.wikipedia.org/wiki/PH

I am not sure whether I understand your question properly, though...

 

[NoOneKnows]

Higher pH is less acidic.
https://simple.wikipedia.org/wiki/PH

I am not sure whether I understand your question properly, though...

ah yes, ok so as PPI make stomach less acidic, just as well as Zantac why not reccomend them ?

 

[Escaper Boy]

Considering the taste of SN would be very salty and terrible, I was thinking if I could put the SN inside empty capsules instead of mixing the SN into the water and drink it. Because I studied Pharmacy before, I did have experience with drug encapsulation. The only problem is...

Where the heck that thing is sold? I don't think I can buy empty capsules from the drug store (that would be silly, lol). I don't want to order online because I don't live alone. Other alternative would be buying other otc drugs which already encapsulated, remove the powder inside, then replace it with SN. But, that seems like a ton of work.

 

[jayfox]

Seems SN will be my choice since my money for N is gone. I seem to have all the questions answered but one:

Can you take a very strong anti psychotic in a very large dose before or soon after you take the SN ? So you fall asleep faster before the bad stuff comes. Ty

 

[Nanami]

Does anyone know how anemia and hypotension would meddle with SN?

 

[Syn1991]

Seems SN will be my choice since my money for N is gone. I seem to have all the questions answered but one:

Can you take a very strong anti psychotic in a very large dose before or soon after you take the SN ? So you fall asleep faster before the bad stuff comes. Ty

anti psychotic cannot be taken with antiemetics so you are better off taking benzo instead.

 

[drakewantstogo]

Considering the taste of SN would be very salty and terrible, I was thinking if I could put the SN inside empty capsules instead of mixing the SN into the water and drink it. Because I studied Pharmacy before, I did have experience with drug encapsulation. The only problem is...

Where the heck that thing is sold? I don't think I can buy empty capsules from the drug store (that would be silly, lol). I don't want to order online because I don't live alone. Other alternative would be buying other otc drugs which already encapsulated, remove the powder inside, then replace it with SN. But, that seems like a ton of work.

you can order them through amazon to a deliver point

What order do you take the acid regulator, anti vomit pills and SN and what are the time intervals?
Hope I phrased that okay

Yeah, it's on the wiki too. You should read it for your safety.
Anyway, you can take either a stat dose of 30mg metoclopramide 1h before SN or do a regime 48h before SN of 10mg every 8 hours. Then, if you want, you can take an acid regulator 40 minutes before SN. Then, 15-20mg SN diluted in water.
I hope everything is clear

 

[jayfox]

anti psychotic cannot be taken with antiemetics so you are better off taking benzo instead.

Damn.
Problem is im benzo tolerant due to heavy doses for my illnesses thats why im on antipsycotics.

Can you tell me what are the benzos of choice? Xanax? Ambien maybe?

 

[drakewantstogo]

Damn.
Problem is im benzo tolerant due to heavy doses for my illnesses thats why im on antipsycotics.

Can you tell me what are the benzos of choice? Xanax? Ambien maybe?

there is no need for benzos, IMO they would make everything harder

 

[jayfox]

there is no need for benzos, IMO they would make everything harder

Could you please elaborate on why?
Ty so much

 

[drakewantstogo]

Could you please elaborate on why?
Ty so much

Since you have a time span of about 15 minutes from taking SN and falling unconscious, the timing is very limited. Also if you blackout you may not take the SN correctly, and also they can have a bad interaction with the other things you're taking

 

[Bentham]

ah yes, ok so as PPI make stomach less acidic, just as well as Zantac why not reccomend them ?

I have no idea, but it should be noted again that he dropped the claim that high gastric pH (low acidity) facilitates SN absorption and now argues that low gastric fluid volume does. If he recommends, or allows as alternative, PPIs and H2 blockers, he should do so by focusing on the effect of their decreasing gastric fluid secretion regardless of whether or not they increase gastric pH.

 

[jayfox]

Since you have a time span of about 15 minutes from taking SN and falling unconscious, the timing is very limited. Also if you blackout you may not take the SN correctly, and also they can have a bad interaction with the other things you're taking

Ty for the clarification.

 

[JustOverIt]

ah yes, ok so as PPI make stomach less acidic, just as well as Zantac why not reccomend them ?

DO NOT USE PPI's: https://8ch.net/suicide/res/36478.html#45815

Was going to upload screen grab of the post but SS is fucking up so can't upload. Just please click the link if you are thinking of using PPI's (even having them in your system 2 weeks before SN ingestion is bad).

 

[NoOneKnows]

DO NOT USE PPI's: https://8ch.net/suicide/res/36478.html#45815

Was going to upload screen grab of the post but SS is fucking up so can't upload. Just please click the link if you are thinking of using PPI's (even having them in your system 2 weeks before SN ingestion is bad).

thank you for sharing the link. So if I understand correctly, PPI are not making SN less toxic, the only problem with them is they supposedly cancel out the hypotension as a result of SN consumption ? In that case its easy, to take benzo or as I planned anyway taking 2 sleeping pills like Zolpidem half an hour before

 

[Davy]

I'm having concern over anti-emetics in Australia, I did find an eBay seller however they require pharmacist advice before selling as stated in the full description.

https://www.ebay.com.au/itm/ANAGRAINE-HYDROCHLORIDE-5MG-PARACETAMOL-500MG-8-TABLETS/182547399120

My question is has any Australian bought Anagraine off eBay successfully? Did it require a phone interview with the seller? If so how did you go about it?

I bought from this exact place! There's no phone interview or anything, they just shipped it and it arrived quick. I'm guessing they just put that procedure there for legal purposes but don't follow it.

 

[drakewantstogo]

DO NOT USE PPI's: https://8ch.net/suicide/res/36478.html#45815

Was going to upload screen grab of the post but SS is fucking up so can't upload. Just please click the link if you are thinking of using PPI's (even having them in your system 2 weeks before SN ingestion is bad).

So, then, zantac or tagamet is good to go right?

 

[Escaper Boy]

I just finished putting 25g~30g of SN into gelatine capsules. I was surprised I had to encapsulate 25+ pieces, not exactly an enjoyable process. The surface was sticky against pretty much everything (plastic, tissue, skin contact, the SN itself). It was difficult to keep the final product "clean" and "hygiene" (if you get what I mean).

I think swallowing 25+ SN pills would be easier compared to drinking 100ml of salty liquid. Hopefully...

 

[spanishguy22]

View attachment 10376

I just finished putting 25g~30g of SN into gelatine capsules. I was surprised I had to encapsulate 25+ pieces, not exactly an enjoyable process. The surface was sticky against pretty much everything (plastic, tissue, skin contact, the SN itself). It was difficult to keep the final product "clean" and "hygiene" (if you get what I mean).

I think swallowing 25+ SN pills would be easier compared to drinking 100ml of salty liquid. Hopefully...

Isn't that a lot of swallowing? I imagine it may be mentally more difficult as well, your SI may kick in by the time you swallowed half or less. But I guess same goes for liquid.

 

[Escaper Boy]

Isn't that a lot of swallowing? I imagine it may be mentally more difficult as well, your SI may kick in by the time you swallowed half or less. But I guess same goes for liquid.

Yeah, I am worried about SI too. But, at least I don't have to deal with terrible SN taste (whatever it tastes like, I don't even know. Lol). And it seems to be slightly less risky of throwing up. Hopefully... (again)

 

[Isabelx]

Does anyone know if prochlorperazine buccal tablets will be an okay antiemetic for SN? They're one of the few I can find online in UK and it says it's a dopamine blocker which is one of the things people seem to be emphasising on this thread so that's a good sign I think. I was just asking because they're available online (you have to take a survey where they ask your symptoms/condition and see if it's appropraite medication for you but that's it) so I was just wondering if it will be strong enough for SN poisoning.

Is anything else required for this method (other than the SN itself)? I've seen a few people mention benzos but they seem like they could be tricky to get my hands on (it normally takes a couple of weeks to get an appointment at my GP and I was hoping to not have to wait that long). How necessary are they and is there something else I could use instead? Thank you!