Method SN - Diphenhydramine & Ondansetron as alternatives for benzos & meto

[FadingSnowFake]

I obtained Ondansetron 8mg (as HCl – 2H2O, drug name Onsia) in the place of meto, and Diphenhydramine HCl 50mg (drug name PHeNZ, a sleep aid) in place of benzos. Apologies if I'm repeating questions, as I'm confused about what may or may not work with SN. I would like to test the meds next weekend and would appreciate your thoughts.

In my mind, a solid anti-emetic is more important than a relaxing sedative, since we want to prevent vomiting but a sedative to calm the nerves can also be helpful. It appears ondansetron may also cause drowsiness, then perhaps it could be used as anti-emetic and sedative? I doubt diphenhydramine could alleviate nausea caused by SN, but some "individuals with emetophobia (fear of vomiting) found that it helps settle their stomach and reduces anxiety related to nausea." I'd rather leave something which may cause an unwanted reaction but ideally want to take something in the place of both benzos and meto.

More from Google:

1. Meto vs ondansetron: it appears metos are the only "GI stimulant", but ondansetron is "sometimes prescribed off-label for conditions such as nausea and vomiting during gastroenteritis." Metoclopramide works by blocking dopamine D2 receptors in the brain, which helps to reduce nausea and vomiting. It also enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying without increasing gastric acid secretion.

Ondansetron works by blocking the action of serotonin, a neurotransmitter that can induce nausea and vomiting when it binds to specific receptors in the brain and gastrointestinal tract. By inhibiting these receptors, ondansetron reduces the sensation of nausea and prevents vomiting. Side effects may include headache, dizziness, fatigue, constipation, and drowsiness.

2. Benzos vs Diphenhydramine: Benzodiazepines are used to treat anxiety disorders, insomnia, and seizures. They work by slowing down activity in the brain and nervous system, which can help alleviate symptoms of anxiety and promote sleep.

Diphenhydramine is used as a short-term treatment for insomnia, helping individuals fall asleep more easily. It can be an effective treatment for nausea, particularly in cases of motion sickness or anxiety-related nausea. However, there is the possibility of experiencing nausea itself (high doses) and it can cause an upset stomach.

Thanks for your time.

 

[cowboypants]

Ondansetron is pretty solid on its own.

The amount of benzos PPH recommends is to induce deep unconsciousness fast, you won't hit near that level without strong meds. Antihistamines won't do much, but it's also better than not having any

 

[swankysoup]

Benzos aren't needed are they? Aren't they supposed to just make it more comfortable?

 

[FadingSnowFake]

Benzos aren't needed are they? Aren't they supposed to just make it more comfortable?

Yes, as far as I know really only SN is needed, but with my luck I'd rather stick to the recommended protocol as best possible.

 

[what]

DPH is a great (and undaraidet) sedative for the protocol, and i will be using it on my protocol aswell for the following reasons:

1. it will actually help you lose conscious faster
2. it numbs your tastebuds and throat! great for swallowing the SN if you wait long enough (30-60 minutes prior to taking the SN)
3. it blocks acetylcholine, so you will not sweat, which adds a lot more comfort to the process
4. decreases anxiety and stomach overreactivity
5. very good with blocking nausea, take it with meto and you have OP anti-nausea

i know all of these effects and can personally vouch. i use DPH frequently for good sleep
you mentioned upset stomach and dizziness, but these hardly come with the effects
if DPH is the only active ingredient in the medication (benadryl), you will not get an upset stomach
dizziness & nausea hardly comes, unless you take a delirious dose. generally you will only feel your limbs getting heavier

its very important to dose it correctly, because its easy to go from the therapeutic side effects to the bad and delirious ones
if you never/rarely use DPH, 50-75 mg is perfect
if you have experience and use DPH frequently (like me), a fap dose (100-200 mg) is good

oh and its best not in a dark/dimly lit room during the process. you might see unpleasant things, especially when multiplied with SN's own delirious and lucid side effects

 

[thedarkdog]

DPH is no replacement for Benzos, it just not sedating enough.
Less sure about Ondansetron, it does sound like a fair alternative to MCP from googling: https://pmc.ncbi.nlm.nih.gov/articles/PMC7199832/

 

[FadingSnowFake]

DPH is a great (and undaraidet) sedative for the protocol, and i will be using it on my protocol aswell for the following reasons:

1. it will actually help you lose conscious faster
2. it numbs your tastebuds and throat! great for swallowing the SN if you wait long enough (30-60 minutes prior to taking the SN)
3. it blocks acetylcholine, so you will not sweat, which adds a lot more comfort to the process
4. decreases anxiety and stomach overreactivity
5. very good with blocking nausea, take it with meto and you have OP anti-nausea

i know all of these effects and can personally vouch. i use DPH frequently for good sleep
you mentioned upset stomach and dizziness, but these hardly come with the effects
if DPH is the only active ingredient in the medication (benadryl), you will not get an upset stomach
dizziness & nausea hardly comes, unless you take a delirious dose. generally you will only feel your limbs getting heavier

its very important to dose it correctly, because its easy to go from the therapeutic side effects to the bad and delirious ones
if you never/rarely use DPH, 50-75 mg is perfect
if you have experience and use DPH frequently (like me), a fap dose (100-200 mg) is good

oh and its best not in a dark/dimly lit room during the process. you might see unpleasant things, especially when multiplied with SN's own delirious and lucid side effects

Thank you very much for this, it makes sense. However, I decided to skip the DPH and rather keep it simple. Fyi:

Post in thread 'Medication/Substance Thread' https://sanctioned-suicide.net/threads/medication-substance-thread.215670/post-3182834