If you don't have friends, it might help to look for like-minded people online, for example here or on Meetup, Facebook, or disability forums (if you have disabilities), and so on.
But I can't really give more tips, especially if you suffer from poverty and ugliness. I've never really had friends, sadly. I assume from my experiences, I'm too physically and emotionally unattractive and poor for that kind of connection. My interests and worldview aren't mainstream either. I'm more interested in antinatalism, 6B4T, veganism, I read r/antipsychiatry, r/ugly or like lesbian separatist topics. I also play some video games and watch or read true crime and death-related news (who died today or in the last years mostly on needtoknow or people magazin or some german news magazins).
Most of the time, I just lie in bed, waiting for organ failure or my birthday to CTB. Maybe I'm too bitter for many people. I don't like being alive. I've mostly had negative interactions with others who often feel disgust toward me. Many in my area are very malevolent and try to harm me. They also are passiv aggressive. The only family member I have some contact with is my mother, who sometimes brings me food to the door. I am a extremely outcast and seen as ugly, r'tard. It's bad similar to "Lolcows". Very sad and it makes angry. Others have relationships and a purpose in life. I don't even have access to health care, painkillers, physiological diagnosis. I have pain near my kidneys and my body smells like ammoniac. I just hate to be here.