Clonidine overdose

[i0nny]

Reading from this source https://www.ncbi.nlm.nih.gov/books/NBK459374/ it take somewhere between 10-20 micrograms of clonidine per kg of body weight to od on so If someone weighs about 85kg so that would mean that they would need about 1.7mg (assuming 20micrograms per kg of body weight is used as a factor) to od on?

 

[Darkover]

In mice and rats, the oral LD50 of clonidine is 206 and 465 mg/kg, respectively

 

[i0nny]

In mice and rats, the oral LD50 of clonidine is 206 and 465 mg/kg, respectively

There's no way that 17-40g would be roughly required to kill a human I honestly think it's way lower and reading from that source it's greater than 0.01-0.02mg/kg so I think 2mg would probably kill an 85kg person

 

[Darkover]

There's no way that 17-40g would be roughly required to kill a human I honestly think it's way lower and reading from that source it's somewhere around 0.01-0.02mg/kg

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globalrph.com

Symptoms of acute overdosage include nausea, weakness, dizziness and disturbances of electrolyte balance. The oral LD50 of the drug in the mouse and the rat is more than 25,000 mg/kg body weight. The minimum lethal dose (MLD) in humans has not been established. There is no specific antidote but gastric lavage is recommended, followed by supportive treatment. Where necessary, this may include intravenous dextrose-saline with potassium, administered with caution.