OP, have you read Stan's Guide? How much research on SN have you done? Use the search function on this site if you haven't already.
All you actually need to catch the bus with SN is SN itself. That's the only component that kills you.
BUT, the other medications can increase the likelihood of catching the bus and can also increase comfort during the process.
Every method has a risk-profile that you have to assess according to your own personal circumstances, finances, privacy etc. No one on this site can make any sort of decision for you - ultimately it all comes down to what you want and what you're willing to do to fulfil your own wishes.