Quetiapine as Antiemetic

[Mimikyu]

Hi everyone,

I've been trying to conduct research on possible antiemetic alternatives since I can't get meto. I've read that Quetipaine can act as a Dompamine blocker. Does anyone have more information on that? What's the best dosage for it to be an effective antiemetic?

Any info is appreciated.

Thanks!

 

[autumnal]

Hi everyone,

I've been trying to conduct research on possible antiemetic alternatives since I can't get meto. I've read that Quetipaine can act as a Dompamine blocker. Does anyone have more information on that? What's the best dosage for it to be an effective antiemetic?

Any info is appreciated.

Thanks!

To put it mildly, there is some debate on the forum about this question.

What little consensus there is suggests that it only works as an antiemetic if you are already taking it regularly (i.e. prescribed for psychiatric purposes) and so it has built up in your system. A regularly-taken dosage that should have antiemetic effects could be 300-400mg per the thread linked above.

If you are not already taking it regularly, a single dose of those quantities will probably not work as an antiemetic.

 

[Mimikyu]

To put it mildly, there is some debate on the forum about this question.

What little consensus there is suggests that it only works if you are already taking it regularly (i.e. for psychiatric purposes) and so it has built up in your system. A regular dosage that should have antiemetic effects could be 300-400mg per the thread linked above.

If you are not already taking it regularly, a single dose of those quantities will probably not work as an antiemetic.

I only take it 25mg every night to help me sleep. Do you think it would still be effective?

 

[autumnal]

I only take it 25mg every night to help me sleep. Do you think it would still be effective?

My opinion would be no, as described here and based on the drugsclassroom link quoted therein. It's the dopamine receptors that need to be targeted to reduce nausea, and Quetiapine only targets those at high doses (300mg+).