T
thenobrainer
Member
- Feb 18, 2026
- 12
I'm thinking of consuming 10mg of domperidone and also 5mg of prochlorperazine, and about 45 minutes later, 3 gm of Amitriptyline (which is about 40 of 75mg pills), and also consumed half a litre of vodka. Because the first two tablets make sure you don't puke (and bonus: they're also CNS Depressants), and the Amitriptyline is a tricyclic antidepressant, I have done my research, and 3g is a lethal dose, and the alcohol is to take the edge off and also to help amplify the effects of the drugs.
What do y'all think? Is this a decent plan that I should go through?
Also, was doing some research and found this:
pmc.ncbi.nlm.nih.gov
So looks like I can overdose on this.
What do y'all think? Is this a decent plan that I should go through?
Also, was doing some research and found this:
Prolonged Toxicity after Amitriptyline Overdose in a Patient Deficient in CYP2D6 Activity - PMC
Amitriptyline and its metabolite, nortriptyline, are metabolized, in part, by CYP2D6, a polymorphic enzyme. About 8% of Caucasians are deficient in CYP2D6 activity. We present the case of a comatose woman who intentionally overdosed on amitriptyline ...
So looks like I can overdose on this.
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