Hey there, I just had a ready of Life sucks account of the person he saw die from SN/Morpdhine/Diaz. A couple of things that I noted. Life Sucks said that at 3pm the person tool 1 Sevredol and in brackets next to it was (Slow release Morphine tablet). However, Sevredol, is NOT a slow release Morphine tablet, it is the opposite, it is a fast release Morphine Tablet. It comes in 10mg and 20mg, either one would have been effective, so it would have had an immediate effect on the person taking it, so thats interesting in itself as that is a big over sight. On top of that this person also had 10mg of Diazepam. Now I dont know whether this person was a drug naive person or someone that was used to taking prescription medication including sedatives like diazepam, but in a naive person, 10mg of Diazepam would have you feeling extremely relaxed. Perhaps the most significant factor in this is the person was anorexic. Someone that is anorexic is already extremely compromised, they would be dehydrated,have low blood glucose,be anaemic, have low blood pressure,an extremely slow or irregular heartbeat, low white blood cell count, liver& kidney probs, most likely changes in the structure of their brain. osteoporosis, abdominal and gastric distress and if their female i could start listing hormonal problems.... so when you start with this kind of physical setting and then you add SN& Diazepam & Sevredol, I wouldnt be asking myself about the doses of Medication this person took as if that could have altered the outcome. If you were starting with a clean slate then you could ask some legitimate questions and get some legitimate answers, do you know what I mean??? There is nothing that you can really learn here, not from someone that is this physically compromised. Which reminds me, the other symptom that Life Sucks mentioned in addition to the anorexia was that this person had liver problems or liver disease so...... I rest my case. With regards to an adequate sedative or Opioid, I mean something like Diazepam or Sevredol would work well,if the idea is to try to be a relaxed as possible. You would want to have as much preparatory work done beforehand if you were intending to take a sedative or opioid before SN. This would be particularly impt if you were opioid or sedative naive. If it were me, I would want to at least try the drug out a few times to see what it was like, see how i was effected by it, was i so incapacitated that i couldnt do anything???? As a naive user obviously you would take the drug orally there would be no point in getting into a discussion around using IV. The only purpose of using IV is t get high and that is not what this is about. So the IV question you asked at the beginning i guess has been resolved? The question remains as to the purpose of the sedative or opioid? Is it just to relax before taking the SN or is it to increase the toxicity? Are you hoping for an increased combinatorial toxicological effect?