Resource Metoclopramide research

[faust]

Hello, as long as I am a bit afraid of taking Meto because of having akathisia and dystonia in the past, I would like to share with you a bit of information.
I selected more interesting researches on Meto, because there are a lot of them and they give us nothing in our case.
If you are interested in the subject, feel free to read.
I have chosen the most comfortable ways for you to download and read since https://www.ncbi.nlm.nih.gov/ is not providing us enough information and referring to websites where you have to pay for articles. There are yet three articles where request is needed though.
Enjoy!

Warning! Dystonia and akathisia are extremely rare to those who never experienced something like that before. Anyway, you have to start from 5-10 mg of Meto and see how your body reacts. Especially those of you who have seizures/akathisia/dystonia. Some of the cases mentioned are so uncommon that you are more likely to be struck by a lightning rather than getting these symptoms.
This thread is just for educational purposes so that you could know that such occasions exist. ​

Acute dystonia associated with fluvoxamine-metoclopramide.

Author(s): Palop V, Jimenez MJ, Catalan C, Martinez-Mir I.

Source: The Annals of Pharmacotherapy. 1999 March; 33(3): 382.

https://booksc.xyz/book/39841289/335592



Akathisia, panic, agoraphobia, and major depression following brief exposure to metoclopramide.

Author(s): Anfinson TJ.

Source: Psychopharmacology Bulletin. 2002 Winter; 36(1): 82-93.

https://www.researchgate.net/public...on_following_brief_exposure_to_metoclopramide

Request only!



Cardiac arrest after intravenous metoclopramide - a case of five repeated injections of metoclopramide causing five episodes of cardiac arrest.

Author(s): Bentsen G, Stubhaug A.

Source: Acta Anaesthesiologica Scandinavica. 2002 August; 46(7): 908-10.

https://booksc.xyz/book/5056246/0b590e



Diltiazem and metoclopramide overdose.

Author(s): Beno JM, Nemeth DR.

Source: Journal of Analytical Toxicology. 1991 September-October; 15(5): 285-7.

https://booksc.xyz/book/39948113/2c61ad



A Single Dose of Metoclopramide Associated with Extrapyramidal Symptoms in a Child: A Case Report

https://juniperpublishers.com/jojcs/pdf/JOJCS.MS.ID.555740.pdf



Familial metoclopramide-induced dystonic reactions.

Author(s): Guala A, Mittino D, Fabbrocini P, Ghini T.

Source: Movement Disorders : Official Journal of the Movement Disorder Society. 1992

October; 7(4): 385-6.

https://booksc.xyz/book/1810382/6210e3



Index of Suspicion. Case 1. Dystonic reaction to metoclopramide.

Author(s): Stille CJ.

Source: Pediatrics in Review / American Academy of Pediatrics. 1997 February; 18(2):

63, 64.

https://www.researchgate.net/publication/8249792_Index_of_Suspicion





Metoclopramide-induced methemoglobinemia in an adult.

Author(s): Mary AM, Bhupalam L.

Source: J Ky Med Assoc. 2000 June; 98(6): 245-7.

https://www.researchgate.net/public...pramide-induced_methemoglobinemia_in_an_adult

Request only



Metoclopramide-induced supersensitivity psychosis.

Author(s): Lu ML, Pan JJ, Teng HW, Su KP, Shen WW.

Source: The Annals of Pharmacotherapy. 2002 September; 36(9): 1387-90.

https://booksc.xyz/book/40853126/484c69



Respiratory failure following oral administration of metoclopramide.

Author(s): MacLaren R, Shields CA.

Source: The Annals of Pharmacotherapy. 1998 October; 32(10): 1017-20.

https://booksc.xyz/book/44597272/a8cc99



Serotonin syndrome caused by selective serotonin reuptake-inhibitors metoclopramide interaction.

Author(s): Fisher AA, Davis MW.

Source: The Annals of Pharmacotherapy. 2002 January; 36(1): 67-71.

https://booksc.xyz/book/34264148/0d13d1


Sudden death after acute dystonic reaction to high-dose metoclopramide

https://booksc.xyz/book/25362627/6e1079



Suicide attempt due to metoclopramide-induced akathisia.

Author(s): Chow LY, Chung D, Leung V, Leung TF, Leung CM.

https://www.researchgate.net/public...tempt_due_to_metoclopramide-induced_akathisia

Request only.



Tardive tremor due to metoclopramide.

Author(s): Tarsy D, Indorf G.

Source: Movement Disorders : Official Journal of the Movement Disorder Society. 2002

May; 17(3): 620-1.

https://booksc.xyz/book/1805113/c7f6c5



The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide.

Author(s): Seaber EJ, Ridout G, Layton G, Posner J, Peck RW.

Source: European Journal of Clinical Pharmacology. 1997; 53(3-4): 229-34.

https://booksc.xyz/book/7426445/e203ea



Withdrawal effects of metoclopramide.

Author(s): Noll AM, Pinsky D.

Source: The Western Journal of Medicine. 1991 June; 154(6): 726-8.

https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1002885&blobtype=pdf

 

[HelensNepenthe]

(You're able to find articles that are behind paywalls with Sci-Hub)

 

[faust]

(You're able to find articles that are behind paywalls with Sci-Hub)

True, but not the ones which are request-only.
Oh, it works with Springer, thanks a million!

 

[jgm63]

Isn't quoting all of these a bit like telling someone to have a read through a medical encyclopedia (by the end of which you'll believe you have every condition listed) ?

I don't see much benefit coming from making this thread.
If we speak of negative effects, we should also state how common we think they are....

I have sometimes written about EPS in some of my posts, but I always try to state that it is not common....

 

[faust]

Isn't quoting all of these a bit like telling someone to have a read through a medical encyclopedia (by the end of which you'll believe you have every condition listed) ?

I don't see much benefit coming from making this thread.
If we speak of negative effects, we should also state how common we think they are....

I have sometimes written about EPS in some of my posts, but I always try to state that it is not common....

If it was spoken about side effects, there would not be so many people suffering after prescribed medication. That's the first thing.
The second thing, there are people who are prone to side effects mentioned in the thread. So it would be much better to look up for a more safe alternative rather than just pushing people to take meto regimen who do not know that it may trigger their symptoms.

 

[jgm63]

If it was spoken about side effects, there would not be so many people suffering after prescribed medication. That's the first thing.
The second thing, there are people who are prone to side effects mentioned in the thread. So it would be much better to look up for a more safe alternative rather than just pushing people to take meto regimen who do not know that it may trigger their symptoms.

Well the general advice given is to start out by testing with a small amount, eg 5mg of meto.
Then build up from there.
This is discussed in various places, eg :

Spoiler: post-517024

https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/post-517024

If you have evidence that supports domperidone being highly effective, then that is worth sharing of course, although note that in general it's better to post a summary and your thoughts/interpretation, and then link to the medical study...

 

[faust]

Well the general advice given is to start out by testing with a small amount, eg 5mg of meto.
Then build up from there.
This is discussed in various places, eg :

Spoiler: post-517024

https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/post-517024

If you have evidence that supports domperidone being highly effective, then that is worth sharing of course, although note that in general it's better to post a summary and your thoughts/interpretation, and then link to the medical study...

Thank you for advice! I did not do things like that before, so any constructive critics may help me improve for the future posts :)

 

[faust]

Thread has been updated!