Huh. This is a weird question and responses to me… an NDE has nothing to with drugs (unless you don't believe they're real). From my understanding the more conscious you are at the time of death (ie not asleep and most definitely not under the influence of anything) the better/quicker your NDE/post-death experience will be and start.
Hi, first of all I'm really sorry for not responding in a long while. But secondly, I do think this is a pretty solid way to ctb. Sadly I don't research all of the drugs you mentioned here. But from what I'd found, your antiemetic is pretty solid (though I'd probably choose 60-90 mins prior to make sure both of them works). Now on the concoction, its pretty full of depressants there and from what I can found, Tapentadol works to combine with oxycodone, carisoprodol, and alprazolam to depress your respiratory which could lead to death.
Drug Interaction Report: alprazolam, amitriptyline, carisoprodol, oxycodone, tapentadol
View detailed report of drug-drug and drug-food interactions for alprazolam, amitriptyline, carisoprodol, oxycodone, tapentadol
www.drugs.com
I'd search for tapentadol first but sadly there's no definite lethal dose for that:
Sadly I don't search for the others at the time of the writing. I do know that amitriptyline aren't the leading cause of your ctb since that is an antidepressant and all of the other drugs is a depressant. Same for grapefruit juice.
Now was it reliable? In my opinion, certainly. With combination for drugs like that it's certainly deadly enough to be used as a method of ctb
Was it speedy and peaceful? Yes, since you'll be very likely to just phase out and die after the onset of the drug. If you want to ctb in your own home please make yourself a way to be found to at least make the cleanup far more easier later on (depends on your choice honestly)
The biggest concern for me right now is how do you ingest that concoction? Do you blender all of it into a smoothie or a powder or what exactly? I do want to know about that.
Sure, why not. My DM is open...
I think NDE can be influenced by drugs. Sure, there's also your way of increasing NDE and this paper saying that NDE is still medically inexplainable: https://pmc.ncbi.nlm.nih.gov/articles/PMC6172100/ (This paper is kinda interesting, please check it out). But I do think that some medication can be used to make your chance of NDE happening. Now was it entirely depends on the drugs? Certainly not, but I do think they play a bigger role than most of the people think of.
Last edited:
Thanks for the response. I will take your view on the antiemetics into consideration as well. Now as for ROA, I am thinking of crushing up all of the medications (except for the antiemetics of course) into a fine powder and then putting them inside enteric-coated capsules and taking them with a big glass of grapefruit juice. I have the size 00 capsules. I estimate that I'm gonna need about 70 capsules to fit all that powder (based on the weight & average density of the tablets of medicine). Now the question becomes: is that a viable plan, swallowing 70 capsules in a matter of a few minutes at most? What do you think? I really don't wanna have to mix all that powder into a drink or a cup of applesauce/yogurt or anything of the like as I fear that the risk of severe nausea, vomiting, or even not being able to finish the whole thing in time becomes very high—even after taking the antiemetics. On the other hand, putting all the depressants in enteric-coated, delayed-release capsules means that I'm not gonna lose consciousness for something like 2 hrs right? What is a possible workaround here? Can I take just some of the depressants, crush & mix them into the grapefruit juice, with the rest of the meds being in enteric coated capsules? If so, which ones & how much do I need in order to lose consciousness fast? Would that affect the time that it would take to lose consciousness (as opposed to taking all the meds in powder form directly)?Hi, first of all I'm really sorry for not responding in a long while. But secondly, I do think this is a pretty solid way to ctb. Sadly I don't research all of the drugs you mentioned here. But from what I'd found, your antiemetic is pretty solid (though I'd probably choose 60-90 mins prior to make sure both of them works). Now on the concoction, its pretty full of depressants there and from what I can found, Tapentadol works to combine with oxycodone, carisoprodol, and alprazolam to depress your respiratory which could lead to death.
Drug Interaction Report: alprazolam, amitriptyline, carisoprodol, oxycodone, tapentadol
View detailed report of drug-drug and drug-food interactions for alprazolam, amitriptyline, carisoprodol, oxycodone, tapentadol
I'd search for tapentadol first but sadly there's no definite lethal dose for that:
Sadly I don't search for the others at the time of the writing. I do know that amitriptyline aren't the leading cause of your ctb since that is an antidepressant and all of the other drugs is a depressant. Same for grapefruit juice.
Now was it reliable? In my opinion, certainly. With combination for drugs like that it's certainly deadly enough to be used as a method of ctb
Was it speedy and peaceful? Yes, since you'll be very likely to just phase out and die after the onset of the drug. If you want to ctb in your own home please make yourself a way to be found to at least make the cleanup far more easier later on (depends on your choice honestly)
The biggest concern for me right now is how do you ingest that concoction? Do you blender all of it into a smoothie or a powder or what exactly? I do want to know about that.
Sure, why not. My DM is open...
I think NDE can be influenced by drugs. Sure, there's also your way of increasing NDE and this paper saying that NDE is still medically inexplainable: https://pmc.ncbi.nlm.nih.gov/articles/PMC6172100/ (This paper is kinda interesting, please check it out). But I do think that some medication can be used to make your chance of NDE happening. Now was it entirely depends on the drugs? Certainly not, but I do think they play a bigger role than most of the people think of.
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HI, so I'd like to answer this but maybe its best to do in private since I was uncomfortable answering that in public and because I'd like to respect you (since you sounds like a knowledgeable person in this too). No pressure if you want to stay here though. Do you like to move this into private chat?
jatty
zero emotional regulation
- Nov 13, 2023
- 91
whats your opinion on phenobarbital? Its still moderately prescribed and it seems to be the same mechanism as N.
Generally speaking. phenobarbital is safer than nembutal (pentobarbital). Phenobarbital have lethal dose aroung 6-10 g (https://www.addictionresource.net/lethal-doses/phenobarbital/) and with nembutal is around 2-10 g (https://www.addictionresource.net/lethal-doses/pentobarbital/)
That being said, pure phenobarbital powder is easier to get than nembutal injection. If you cant find nembutal injection, pure phenobarbital powder can be an alternative to your choice. I don't recommend using phenobarbital tablet due to how much you need to ingest to ctb.
Thanks for the post!
I was planning on taking a cardiac switch and some CNS depressants similar to the DDMP method in MAiD:
50mg Digoxin
5g Propranolol
500mg Diazepam
And maybe some weak opioid like codeine or DHC
I have meto and ondansetron to take prior, to limit vomiting.
Do you think this would work?
I was planning on taking a cardiac switch and some CNS depressants similar to the DDMP method in MAiD:
50mg Digoxin
5g Propranolol
500mg Diazepam
And maybe some weak opioid like codeine or DHC
I have meto and ondansetron to take prior, to limit vomiting.
Do you think this would work?
First of all, I'm really sorry for the long wait, I've got some irl stuff to do.
In general, this could work. I don't really get the need for propranolol since only diazepam and digoxin is needed to make the switch works. But I do think that'll work with people that have low weight since the dose needed would be much lower than the DDMAPh protocol. I'd suggest you should:
1. Collect other drugs first, primarily amitriptyline and phenobarbital since morphine is harder to search
2. Increase the dose of digoxin and diazepam you have right now. The target would be the same as DDMAPh needed (digoxin 100 mg and diazepam 1 g). But if you're unable to follow step 1, please increase the dose to make sure that you'll pass out comfortably after using it
3. Do both to make sure the DDMAPh protocol works perfectly.
4. Using diazepam, propranolol, and digoxin as a additive for other methods, primarily SN. Propranolol is used to reduce your anxiety, and both diazepam and digoxin as a sedative before you take SN.
That's ok, thanks for taking the time to respond.
I think you might be mistaken. It's propranolol/amitriptyline and digoxin that causes the cardiac switch, not diazepam.
The diazepam is for sedation so you are unconscious during the cardiac event.
The DDMP method is slightly different to the 5 drug mix. It was what MAID used initially before they switched out the propranolol to amitriptyline and added the Phenobarbital.
Unfortunately phenobarbital and morphine are near impossible for me to source at the moment. I may have to abandon the method as the risk is too high at the moment.
unluckysadness
Warlock
- Jul 9, 2025
- 717
I'd like to be uncouscious really fast after drinking SN. When should I take 300mg valium . Just after drinking SN as they say in the PPH ? Can the body vomit after being uncouscious ?
And what do you think about propranolol ? I take 10mg everyday since years because my heart beats so fast. The PPH says it's optional with SN method. Thanks
And what do you think about propranolol ? I take 10mg everyday since years because my heart beats so fast. The PPH says it's optional with SN method. Thanks
FadingSnowFake
Enlightened
- Nov 25, 2024
- 1,280
Hi there, thank you for your time in answering our questions. I'd like to ask your advice on when to take Diphenhydramine in the stat SN protocol please. I have paracetamol and ondansetron in addition to 400mg Diphenhydramine for a sedative/calming effect. I may be wrong, but don't see the point of taking it after SN, or with too little time before SN.
If I take the AE (3 x 8mg) 40 mins before SN, when do you suggest taking Diphenhydramine to be of value? From what I read, I'm almost thinking it may be best to leave it as it may overcomplicate things, or even cause nausea? Fyi, this is what I found with my own research:
sanctioned-suicide.net
I tried testing with one tablet on separate occasions, but I'm not sure if one can really test it properly. It had no effect, but is there a better way to test the meds?
If I take the AE (3 x 8mg) 40 mins before SN, when do you suggest taking Diphenhydramine to be of value? From what I read, I'm almost thinking it may be best to leave it as it may overcomplicate things, or even cause nausea? Fyi, this is what I found with my own research:
SN - Diphenhydramine & Ondansetron as alternatives for benzos & meto
I obtained Ondansetron 8mg (as HCl – 2H2O, drug name Onsia) in the place of meto, and Diphenhydramine HCl 50mg (drug name PHeNZ, a sleep aid) in place of benzos. Apologies if I'm repeating questions, as I'm confused about what may or may not work with SN. I would like to test the meds next...
sanctioned-suicide.net
I tried testing with one tablet on separate occasions, but I'm not sure if one can really test it properly. It had no effect, but is there a better way to test the meds?
1. If you want faster onset, I suggest Xanax (alprazolam). But if you only have diazepam (valium), go for step 2.
2. You should time the onset of the valium since everyone have different onset of the same drug. I assume you had 5 mg tablet, so you have around 60 tablet. Here's how you do it:
- Make sure you're alone or have someone you can trust nearby. You can do this by recording yourself if you want to.
- Prepare yourself a stopwatch and a tablet of valium.
- Take the tablet of valium and start the timer immediately. Stay relaxed but don't do any activities that can distract you (eg. cooking or watching tv) after you take it.
- Take notice of your body's feelings. If you suddenly feel calm, relaxed, or drowsy, please stop the stopwatch immediately. If you record yourself, pause at the time you start to feel the same feeling.
- If you're unsure of your onset time, you can do this on the next day so the diazepam clears itself first before you start over.
The time you're starting to feeling calm is your onset of valium. Let's assume you have 15 minutes for valium to sedate you.
PS: You can try the same if you had other sedatives like Xanax
3. On the day you CTB, here's how you do it:
- Make sure you had taken your antiemetics and prepare the SN and valium solution. Make sure you had the timer around 10 minutes (or roughly 75% of your onset time)
- Drink the valium solution and set the timer immediately.
- When the timer ends, drink the SN so that you're still conscious to make sure you're drinking all of it.
- Lay back and relax as you've passed away
As for the vomiting risk, it has been noted as a risk on sedation. Here's a reading if you want to read it:
Crisis management during anaesthesia: regurgitation, vomiting, and aspiration | BMJ Quality & Safety
Pulmonary aspiration during procedural sedation for colonoscopy resulting from positional change managed without oral endotracheal intubation - PMC
Pulmonary aspiration under anaesthesia is a feared complication. It is likely that the incidence of aspiration occurring during procedural sedation is underreported; although rare, fatalities do occur. The supine position increases the risk of ...
pmc.ncbi.nlm.nih.gov
1. You should make sure your head is higher than your stomach to make sure your gastric contents stay below your mouth and preventing vomiting. I highly suggest you sit upright with your body and head leaning on a hard surface. The best example I can give is when you're sitting on an office chair.
2. If you're forced to sleep, make sure your head is supported by a pillow so the head is higher than your stomach is.
As for propranolol, I do think you should add that with your valium solution. It works to calm your heart and in a way calm your SI before you've CTB.
I'm truly sorry for my mistake. I didn't read too much on PPEH.
Still I do think that dosage is too small to make sure you CTB. Glad you've postponed them for later preparations.
I do think DPH can't be your sedative of choice. Since you've relied on DPH's adverse effects and you didn't experience it on the first try, I think taking too much of it might be worse. Since DPH is a deliriant, it might induce hallucinations, psychosis, and even symptoms of anxiety which stops you from taking SN. I highly suggest you've taking sedatives rather than relying on adverse effects of DPH.Hi there, thank you for your time in answering our questions. I'd like to ask your advice on when to take Diphenhydramine in the stat SN protocol please. I have paracetamol and ondansetron in addition to 400mg Diphenhydramine for a sedative/calming effect. I may be wrong, but don't see the point of taking it after SN, or with too little time before SN.
If I take the AE (3 x 8mg) 40 mins before SN, when do you suggest taking Diphenhydramine to be of value? From what I read, I'm almost thinking it may be best to leave it as it may overcomplicate things, or even cause nausea? Fyi, this is what I found with my own research:
SN - Diphenhydramine & Ondansetron as alternatives for benzos & meto
I obtained Ondansetron 8mg (as HCl – 2H2O, drug name Onsia) in the place of meto, and Diphenhydramine HCl 50mg (drug name PHeNZ, a sleep aid) in place of benzos. Apologies if I'm repeating questions, as I'm confused about what may or may not work with SN. I would like to test the meds next...
I tried testing with one tablet on separate occasions, but I'm not sure if one can really test it properly. It had no effect, but is there a better way to test the meds?
Last edited:
FadingSnowFake
Enlightened
- Nov 25, 2024
- 1,280
Thank you kindly. I'll have to go back to pharmacies and try again for OTC sedatives. It was already hard to get DPH without a prescription. I don't know anything about meds. Which is the best "common" sedative they may be likely to give in your opinion (I'm in SE Asia)?
unluckysadness
Warlock
- Jul 9, 2025
- 717
Many thanks for your reply1. If you want faster onset, I suggest Xanax (alprazolam). But if you only have diazepam (valium), go for step 2.
2. You should time the onset of the valium since everyone have different onset of the same drug. I assume you had 5 mg tablet, so you have around 60 tablet. Here's how you do it:
- Make sure you're alone or have someone you can trust nearby. You can do this by recording yourself if you want to.
- Prepare yourself a stopwatch and a tablet of valium.
- Take the tablet of valium and start the timer immediately. Stay relaxed but don't do any activities that can distract you (eg. cooking or watching tv) after you take it.
- Take notice of your body's feelings. If you suddenly feel calm, relaxed, or drowsy, please stop the stopwatch immediately. If you record yourself, pause at the time you start to feel the same feeling.
- If you're unsure of your onset time, you can do this on the next day so the diazepam clears itself first before you start over.
The time you're starting to feeling calm is your onset of valium. Let's assume you have 15 minutes for valium to sedate you.
PS: You can try the same if you had other sedatives like Xanax
3. On the day you CTB, here's how you do it:
- Make sure you had taken your antiemetics and prepare the SN and valium solution. Make sure you had the timer around 10 minutes (or roughly 75% of your onset time)
- Drink the valium solution and set the timer immediately.
- When the timer ends, drink the SN so that you're still conscious to make sure you're drinking all of it.
- Lay back and relax as you've passed away
As for the vomiting risk, it has been noted as a risk on sedation. Here's a reading if you want to read it:
Crisis management during anaesthesia: regurgitation, vomiting, and aspiration | BMJ Quality & SafetyI do think this can be prevented by fasting and eating antiemetics as the protocol suggests. However, I do want to point out to the position after you've drinking SN and valium:Pulmonary aspiration during procedural sedation for colonoscopy resulting from positional change managed without oral endotracheal intubation - PMC
Pulmonary aspiration under anaesthesia is a feared complication. It is likely that the incidence of aspiration occurring during procedural sedation is underreported; although rare, fatalities do occur. The supine position increases the risk of ...
1. You should make sure your head is higher than your stomach to make sure your gastric contents stay below your mouth and preventing vomiting. I highly suggest you sit upright with your body and head leaning on a hard surface. The best example I can give is when you're sitting on an office chair.
2. If you're forced to sleep, make sure your head is supported by a pillow so the head is higher than your stomach is.
As for propranolol, I do think you should add that with your valium solution. It works to calm your heart and in a way calm your SI before you've CTB.
This is really informative. I have huge gastric reflux these days and I often have digestive issues, so I have doubts with this method now. I really don't want to fail, but every method is risky...Acute aspirin poisoning
Swallowing of aspirin and similar medications (salicylates) can lead to rapid (acute) poisoning due to an overdose. The dose necessary to cause acute poisoning, however, is quite large. A person weighing about 150 pounds (68 kg) would have to consume more than 30 325-milligram aspirin tablets to develop even mild poisoning. An acute aspirin overdose, therefore, is seldom accidental, but concentrated salicylate products intended to be applied to the skin, such as oil of wintergreen (methyl salicylate), do cause accidental poisonings.
In acute aspirin poisoning, the first symptoms are usually:
Nausea and vomiting
Rapid or deep breathing
Ringing in the ears
Sweating
Later, if poisoning is severe, the person can develop light-headedness, fever, drowsiness, hyperactivity, confusion, seizures, destroyed muscle tissue (rhabdomyolysis), kidney failure, and difficulty breathing.
(https://www.merckmanuals.com/home/injuries-and-poisoning/poisoning/aspirin-poisoning)
measuremeasure
Member
- Sep 13, 2024
- 26
Hi, bit of a late response, but I was wondering about the combo of GBL/GHB, alprazolam, zolpidem, and alcohol? Or at least the GBL/xanax combo. I know that 1,4 butanediol conflicts with alcohol and neutralizes somehow instead of increasing the CNS depressant effects, so I was wondering if any of these in combination with GBL would be more or less effective? I've tried straight xanax and ambien before but woke up and threw up for a while without incident.
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