Yes, I get infusions about once a month. It does stop my suicidal ideation for a week or so and dampens the thoughts, but they are still there. And I impulsively attempted (and obviously failed) in January. So it hasn't cured me, but I'd credit ketamine with keeping me alive for the most part.
I dissociate only slightly during my treatments; it's not a hard or bad trip and it's not meant to be since the dose given is medicinal, not recreational. I've never had side effects other than a slight headache on a few occasions, never any disorientation that wouldn't be unexpected after being under anesthesia. An anesthesiologist administers my infusions and I'm monitored the entire time (vitals, periodic check in by a nurse). I usually just listen to groovy music and kick back, then nap for an hour afterwards.
I've been getting infusions since 2017. I won't switch to the nasal spray. It's not even the same drug, only similar. And it's shown to have a poor absorption rate. It's more expensive than my infusions too. Neither are covered by insurance.
You need about six IV treatments over a two week period upfront to have a chance at ketamine working for you. And it's important not to let too much time pass between boosters.
I know people getting esketamine paid by insurance
My insurance unfortunately won't cover it. It's not the same drug as ketamine either and has a poor absorption rate, so I'm still doing infusions. My anesthesiologist gives me a discount. She's also great about getting me in on a moment's notice — like within hours — for a treatment if I'm suddenly actively suicidal, which often happens right before my cycle because of hormonal changes, I guess.