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Leonard_Bangley39

Leonard_Bangley39

I am a rock. I am an island
Nov 6, 2025
292
A got prescribed Zoloft (Sertraline) and Hydroxyzine about a week and a half ago. I've been taking the Zoloft once when waking up and the hydroxyzine when i wake up, once when i wake up, and once before bed.

In the beginning it would make me feel really drowsy and sluggish at work, but that side effect has gone down lately. It almost feels like they aren't doing anything anymore.

Has anyone else here taken hydroxyzine for depression or anxiety? It's only been a week and a half so i don't expect to feel much from the Zoloft yet, but the doctor the hydroxyzine was supposed to help short term.
 
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A

adamantc

Member
Mar 29, 2026
33
A got prescribed Zoloft (Sertraline) and Hydroxyzine about a week and a half ago. I've been taking the Zoloft once when waking up and the hydroxyzine when i wake up, once when i wake up, and once before bed.

In the beginning it would make me feel really drowsy and sluggish at work, but that side effect has gone down lately. It almost feels like they aren't doing anything anymore.

Has anyone else here taken hydroxyzine for depression or anxiety? It's only been a week and a half so i don't expect to feel much from the Zoloft yet, but the doctor the hydroxyzine was supposed to help short term.
SSRIs like Sertraline are not useful for everyone. It's usual to feel side effects when taking new medications, and this can be raised as an issue with your doctor. If you don't see improvement from the Sertraline after a couple of months, I'd ask your doctor, who may be able to start you on another alternative medicine. Personally SSRIs like Sertraline have not worked on me, and it is important to realise that improvement takes time, and that 'instant' improvement is not a realistic goal. I've never been prescribed an antihistamine like Hydroxyzine for mental health issues, however.
 
Butterfly-death

Butterfly-death

Just let me die already all I do is suffer
Apr 5, 2024
64
I've taken hydroxyzine for anxiety but got off if because all it did was make me sleepy

I don't think it helped my depression but I was on zoloft for that though I got off zoloft too since it wasn't helpful for me

Imo hydroxyzine isn't good plus it's similar to benadryl since it's an antihistamine if that tells you anything and I've seen many people not like it either

Zoloft could help though just give it more time to possibly work, I hope it works out for you!
 
Leonard_Bangley39

Leonard_Bangley39

I am a rock. I am an island
Nov 6, 2025
292
do zoloft or hydrocyzine make it hard to focus your eyes? i feel like ever since i started taking medication its been harder for me to focus my eyes sometimes
 
AnxiousLife

AnxiousLife

scared of people
Jan 13, 2025
48
Hydroxyzine is primarily for anxiety and sleep in psychiatry. It helped me with anxiety a little, when I took it and it also helped me with sleep (faster to fall asleep and sleep was better), but it doesn't have long term effects, it's just until effect wears off. But now I don't take it anymore, as my OCD makes me scarred of some potential side effects, even though I used hydroxyzine for years (just some days) and it was fine. SSRI's didn't help me at all. I hope it gets better for you
 
Leonard_Bangley39

Leonard_Bangley39

I am a rock. I am an island
Nov 6, 2025
292
i slept like shit last night. i had a really violent and unpleasant dream. probably the first time in forever that a dream has actually left me feeling uneasy afterwards. i woke up a few times before my alarm, felt like i was having a fever dream or something. idk if it was because of the medication or not
 

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