I used to smoke weed on a daily basis. It killed my motivation to do my coursework or even go out and socialize, but goddamn, that stuff is heavenly. Now I smoke a few times a month.
A girl I went to high school with introduced me to LSD. The first time we tripped together, it was at the end of a hiking trail somewhere in the mountains, on a ridge that overlooked some lakes. The beauty of the landscape made me forget my depression for the first time since childhood. The second time I tripped was a few weeks after my first attempt, still awfully depressed that I didn't succeed but confident a tab would set me right. This girl and I went out into the woods again, to a different spot. I ended up crying on the ground for hours because I felt like I couldn't breathe, like someone was strangling me.
Had a phase when I abused DXM. Took a ton of Xanax for a bit. Nowadays I just drink alcohol way too much way too often.