Help Doubt regarding antacid

[ashwin]

Hi pph recommends use of antacids for peaceful ctb using sn but in suicide wiki it's written not using antacid will result in a more peaceful death. In wiki its written "Since the release of the October 2018 revision, the PPH suggests Tagamet (instead of sodium bicarbonate) and has misguidedly argued "this effect is not related to gastric pH, but rather to the production rate of acid." While the PPH still incorrectly recommends using H2 receptor antagonists, such as cimetidine and ranitidine, simply not using them will result in a more peaceful death, owing to formation of nitric oxide, a vasodilator, in acidic (Malko, Kucernak & Lopes, 2016) gastric environment—in pH less than 6.51 (Pereira, Ferreira, Rocha, Barbosa & Laranjinha, 2013)—as shown in pathway A[1|2].".

can someone please throw some light on whether one should take antacid or not. Thanks

 

[Debbie Northampton U]

Pph?

 

[Sslsh]

Hi pph recommends use of antacids for peaceful ctb using sn but in suicide wiki it's written not using antacid will result in a more peaceful death. In wiki its written "Since the release of the October 2018 revision, the PPH suggests Tagamet (instead of sodium bicarbonate) and has misguidedly argued "this effect is not related to gastric pH, but rather to the production rate of acid." While the PPH still incorrectly recommends using H2 receptor antagonists, such as cimetidine and ranitidine, simply not using them will result in a more peaceful death, owing to formation of nitric oxide, a vasodilator, in acidic (Malko, Kucernak & Lopes, 2016) gastric environment—in pH less than 6.51 (Pereira, Ferreira, Rocha, Barbosa & Laranjinha, 2013)—as shown in pathway A[1|2].".

can someone please throw some light on whether one should take antacid or not. Thanks

Well from what ive seen on goodbye threads, people have done it with or without it. Don't think it matters much,

 

[Freelyffe88]

I personally think the antacid is more important than the antiemetics and why not, the antacid is the easiest thing to get... it's not like the antiemetic where you have jump through fireballs and suck a dick to get it.

 

[contramundum]

I read somewhere that cimetidine was important to render amitriptyline more deadly, almost doubling its blood levels and to shorten the time lapse until death, precisely because it is a p450 inhibitor. And that, for this same reason, it could not be replaced with ranitidine. But this is for use with amitriptyline, I don't know if the same applies to the use with other substances.