Sometimes I go through life feeling like everything could be a dream and at any moment I could wake up from it and find myself lying in a hospital bed. It all started when I was younger, after watching a video that was talking about how we perceive the world around us via our brains, which means that we have trust that our perceptions and judgements of the world around us are true, since for all you know your entire world just be a product of your mind. Of course, I'm aware that it's unlikely that all of this is just one big dream. Still, the thought gets to me a lot sometimes. Several months back, I remember going through this sort of "episode" as a result of these thoughts and it led me to kind of spiral a bit and I nearly attempted to ctb on impulse as a result.
I also find myself often questioning reality while high on shrooms, though I don't feel distressed whenever I do it while tripping. I feel more intrigued. I think part of why I don't get too stressed out during those times is because I find myself more comfortable with the reality I'm in when high (though I do still usually have a lot of criticisms towards the state of modern society). When I question this, it feels more theoretical in nature rather than like I'm having a sort of existential crisis. I think part of why I question it so much while tripping is partly due to the slight loss of self I go through while I'm in that state. The barrier between me and my environment, the one that allows me to feel like an entity that is completely separate from the world around me, becomes weakened and I feel more connected with my surroundings (probably due to their effects on the DMN). It feels like I'm walking around in a sort of dreamlike state, so it makes sense that everything around me doesn't feel as "real" anymore.