deathbyginger

deathbyginger

Student
Oct 24, 2019
114
I have a crap ton of xanax that I would like to make use of while I CTB. It definitely could help take off the nerves and put me to a peaceful sleep.

Now, my concern is mixing it with any other drugs that I plan on consuming. I've checked using the drugs.com drug interaction tool, and the possible concern sources from the interactions between Xanax and Tagamet, as well as Xanax and Meto.

There is a "moderate" interaction between Xanax and Tagamet, being that it may increase and prolong the effects of Xanax.
Now, this doesn't sound much of a concern being that I don't think I would complain about a stronger Xanax buzz. It would only concern me if it said that it may increase the side effects of Xanax. It's just funny because I already have such a low tolerance to Xanax, meaning that instead of taking 0.5mg (a 1/4 bar), I'll take 0.25mg (1/8 of a bar). This would explain why I have so much of the stuff laying around aha.

The other interaction between Xanax and Meto is marked as "moderate" as well, being that it may increase side effects such as: dizziness, drowsiness, confusion, and difficulty concentrating. I would like to quote the website's professional interaction data rather than attempting to paraphrase it. It states the monitor and management recommendations when combining these drugs.

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Cautious dosage titration may be required, particularly at treatment initiation. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

References
  1. "Product Information. Belsomra (suvorexant)." Merck & Company Inc, Whitehouse Station, NJ.
  2. Plushner SL "Valerian: valeriana officinalis." Am J Health Syst Pharm 57 (2000): 328-35
  3. Feldman SA, Crawley BE "Interaction of diazepam with the muscle-relaxant drugs." Br Med J 1 (1970): 336-8

As you can see, in management it states that all patients should be monitored for excessive or prolonged central nervous system and respiratory depression.
Now, should this concern me? If I'm planning on CTBing anyways... so will it really hurt me?
And I'm unsure if I would even notice these effects being that I don't plan on consuming the xanax til an hour prior to consuming my SN.

I don't know, let me know what you guys think of this.

Although, more interestingly, I came across a study about the increased anti-emetic effects on patients being treated with chemotherapy of using Xanax in addition to Meto: Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis.
This study takes advantage of meto, xanax, and methylprednisolone (an corticosteroid used in chemotherapy to reduce nausea and vomiting), but the main focus was on the addition of xanax to meto and methylprednisolone in traditional chemotherapy treatment. It was concluded that xanax did in fact reduce the duration, severity, and likelihood of vomiting following chemotherapy treatment.

This is my first time actually hearing about methylprednisolone, and it shocks me to think that it hasn't been mentioned in the peaceful pill handbook or anywhere here on this forum. I wonder if it could make any difference in terms when consuming SN. But I'm sure for now, we don't need it to make the SN method effective. It doesn't seem to be something easy to source (based on a google search and a few marketplaces), so it seems like much more of a hassle of obtaining this than worth it.
You by no means need this drug to find success with consuming SN.

I just thought I'd share what I found during my research. I'm open for any comments or critiques.

Side Note: is anyone aware of any possible deadly cocktails involving Xanax? I'm aware that opiods, alcohol, and xanax is one deadly combination but I don't have access to any opiods at the moment (someone actually threw out my Percocet)
 
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metalchic_74

metalchic_74

Gone Girl
Oct 26, 2019
260
I have a bottle of 30 1 mg Ativan. I'm not planning on taking all of them when I consume SN. Maybe just enough to take the edge off.
 
deathbyginger

deathbyginger

Student
Oct 24, 2019
114
I have a bottle of 30 1 mg Ativan. I'm not planning on taking all of them when I consume SN. Maybe just enough to take the edge off.

I can relate, I only need so much to calm me down. Or most importantly, not enough to make me pass out so that way I know I actually am passing rather than just falling asleep.
I'd recommend testing your desired dose before making an attempt. I did the same by taking 1mg of Xanax and that made me pass out, so I now know that I need to be careful on how much I want to consume.
Also note, that you can build tolerance to benzos real fast. I'd test your dosage a week at least a week prior, if not longer, to ensure that you have reset your tolerance to the same level as when you tested it.

Edit: I've just read your most recent post. Scrap what I've said. I hope you find peace soon:hug:
 
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Science Is Scary

Science Is Scary

Evidence is the path to the truth. Maybe.
Oct 17, 2019
87
Are there any other medications you have taken or will take other than those you listed? Antidepressants, for example. Although I think you said in another post you weren't taking any.
 
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D

Daniela

Specialist
Feb 23, 2019
303
I plan to ingest 20-40g Xanax (drops) five minutes before drinking the SN (i.e. after stat dose meto + antiacid)
 
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deathbyginger

deathbyginger

Student
Oct 24, 2019
114
Are there any other medications you have taken or will take other than those you listed? Antidepressants, for example. Although I think you said in another post you weren't taking any.
No, I'm not taking any other medications at this moment. I plan on only consuming: Tylenol, Xanax, Tagamet, and Meto.
I plan to ingest 20-40g Xanax (drops) five minutes before drinking the SN (i.e. after stat dose meto + antiacid)
I'm unsure the consumed dosage from the drops but I would think that's a safe idea as long as you don't over-sedate yourself.
Have you consumed Xanax before? Or perhaps are you prescribed Xanax at the moment?
Also. I plan on doing a 36 hr regimen with the meto and then consuming Tylenol 45 mins prior and Xanax and Tagamet 30 mins prior to my SN.
 
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D

Daniela

Specialist
Feb 23, 2019
303
Have you consumed Xanax before? Or perhaps are you prescribed Xanax at the moment?
Also. I plan on doing a 36 hr regimen with the meto and then consuming Tylenol 45 mins prior and Xanax and Tagamet 30 mins prior to my SN.

I have Tylenol as well, so thanks for adding this detail

I was prescribed Xanax years and years ago, I haven't taken it in years. My mother is taking it as a sleep-inducer.

You're right - 20-40mg is a bit overboard. 10mg should make me nod off quickly enough.
 
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deathbyginger

deathbyginger

Student
Oct 24, 2019
114
I have Tylenol as well, so thanks for adding this detail

I was prescribed Xanax years and years ago, I haven't taken it in years. My mother is taking it as a sleep-inducer.

You're right - 20-40mg is a bit overboard. 10mg should make me nod off quickly enough.
I still believe 10mg of Xanax sounds like a lot unless you've built up quite a bit of tolerance.
4mg of Xanax could easily make you black out if you haven't consumed the drug for awhile.
See here: Xanax Dosage
I would advise against consuming an excessive amount to prevent blackouts. If you're consuming SN, we all know that there is a chance of puking and you sure as hell want to be awake for that, unless you want to risk dying from choking on your puke. Which would likely be much less peaceful.
You may wish to test the dosage of Xanax if you have the chance.
 
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ImsooDone1N

ImsooDone1N

Arcanist
Nov 22, 2018
846
Xanax drops? You mean the intensol concentrate? Or some blackmarket Xanax? And 20-40mg alprazolam is a very high dose. I take 1mg at night & it often makes me pass out. Im not a doctor, but drugs.com will usually list every possible interaction known of. However you can always call a pharmacy & ask to speak to the pharmacist. Assuming you don't mention the SN, they will just think it's a basic question about drug/drug interactions.
 
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deathbyginger

deathbyginger

Student
Oct 24, 2019
114
Xanax drops? You mean the intensol concentrate? Or some blackmarket Xanax? And 20-40mg alprazolam is a very high dose. I take 1mg at night & it often makes me pass out. Im not a doctor, but drugs.com will usually list every possible interaction known of. However you can always call a pharmacy & ask to speak to the pharmacist. Assuming you don't mention the SN, they will just think it's a basic question about drug/drug interactions.
Yeah 1mg of Xanax is more than enough to make someone pass out if they don't have an established tolerance. I personally plan on only consuming 0.25mg of Xanax because of my body weight and lack of tolerance.
I only need enough to calm my nerves, not to fall asleep.
But thank you for the advice about the pharmacist. I will definitely talk to somebody for assurance.
I also did check drugs.com, you can check the top of the thread for information
 
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xBrialesana

xBrialesana

Become Dust With Me, My Love.
Dec 17, 2019
552
Not to randomly bump an old thread, but my tolerance is ridiculous (was given it when I was 12 because my doctors a dumbass, I'm 25 now); I'm going to use it the day I get the refill so i have plenty, but I can literally take 12 and feel no effects. :( same with sleeping pills. ugh. Gimme N and put me to sleep please thank yooou!
 
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xBrialesana

xBrialesana

Become Dust With Me, My Love.
Dec 17, 2019
552
I realized I really rambled there. My point was that my tolerance is so high, I really only take it to stay even/not wd, and I honestly don't think there's any way of me getting peace and calm from it. I also don't wanna take too much (I'm talking about with SN) and get like... sick?? Idk. Yay for dead threads lmao
 

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