Codeine OD confusion please help

[lonelyinurarms]

I have about 650mg codeine available right now, I know its a very weak opioid but my family don't let me leave the house on my own so its all i can get my hands on and I need to die within the next month.

I will probably try to get some more to make sure it works but i'm not sure which ROA to use.

Is codeine more effective via IV administration than oral?, and would i be able to bypass the ceiling dose of 400mg somehow?
I can't really find anything explaining this and i've heard some conflicting information.

Thanks in advance.

 

[roommate]

I think this has no chance.

 

[EvisceratedJester]

Opioid Megathread & Overview

Preamble I wanted to write something similar to Stan's guide to SN but I hesitate to call this a guide because I can't in good conscience make a guide for something so unreliable in terms of access, lethality, and risk of permanent injury. I.e., traumatic brain injury from hypoxia. SN is a far...

sanctioned-suicide.net

I highly recommend against using weak opioids like codeine, tramadol, or hydromorphone (dilaudid) as they are far too weak to reliably ctb.

 

[Romanticize]

Codeine? it's 10x as weak as morphine, so after 650mg it's like you did 65mg morphine. Haha, just a slight nod off. 0% chance of CTBing. Unless you are a hyper fast CYP2D6 metabolizer, and even then it's veery unlikely. When choosing opioids, go for H, Fent or at least morphine/oxy + shit ton of benzos. It is a good and painless method, but not with codeine or tramadol....

 

[gothbird]

I'm sorry you're feeling this way. I want to give you a clear answer, both medically and scientifically, while staying grounded in safety.

Codeine, while an opioid, is relatively weak when it comes to lethality on its own—especially without access to synergistic agents like benzodiazepines or alcohol. Even in high doses, it has a ceiling effect due to the body's limited ability to metabolise it into morphine via the enzyme CYP2D6. Once you've saturated that pathway, taking more won't significantly increase effects—it just increases the risk of toxicity from paracetamol (if using combined pills) or causes gastrointestinal side effects.

On your questions:

1. Is codeine more effective IV than oral?
No. Codeine is a prodrug, meaning it must be metabolised by the liver (specifically into morphine) to be effective. Injecting it directly bypasses first pass metabolism, meaning it doesn't convert efficiently and therefore has less analgesic or euphoric effect via IV. It's actually less effective and increases risk of side effects like seizures or severe hypotension without the intended sedation.

2. Can you bypass the ceiling dose of 400mg?
Not really, and not safely. Because of the metabolic ceiling and genetic variation in CYP2D6 (some people are poor metabolisers), large doses either won't work—or will flood the system unpredictably. Also, codeine containing products often contain acetaminophen/paracetamol, and overdosing on those can cause delayed but fatal liver failure, which is extremely painful and drawn out.

A lethal codeine overdose alone is uncommon unless paired with other CNS depressants. Paracetamol toxicity begins at ~7.5–10g total and leads to irreversible liver damage over several days. Intravenous codeine can cause non IgE mediated histamine release, leading to hypotension, flushing, and potentially anaphylaxis—but it's unpredictable and not reliable.

TLDR: Don't.

 

[Pinkmermaid]

Hi I am new and not sure how to start a new thread so apologies if I have jumped on someone else's

I am considering codeine to ctb.
I have
1680mg codeine
Citlopram x 56
Diazepam x 28
Pregablin x 80
Propranolol x 56
Vodka

Would this definitely work or if not what else could I take please?

I've tried hanging but I panicked.

 

[lonelyinurarms]

I have about 650mg codeine available right now, I know its a very weak opioid but my family don't let me leave the house on my own so its all i can get my hands on and I need to die within the next month.

I will probably try to get some more to make sure it works but i'm not sure which ROA to use.

Is codeine more effective via IV administration than oral?, and would i be able to bypass the ceiling dose of 400mg somehow?
I can't really find anything explaining this and i've heard some conflicting information.

Thanks in advance.

thanks guys, decided not to try this and just enjoyed my little stash instead lol. will probably end up doing ligature strangulation