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J

JellyPenguin

Member
May 17, 2019
15
I'm planning to start with an antiemetic regime including metaclopramide (I have 50mg) and procloroperazine (I have 40mg). Followed by:

1. Paracetamol: I have 8g so far
2. Amitriptyline: I have 280mg.
3. Oxycodone: I have access to 500mg but I am tolerant to opioids.

Do you think it will work in that order? Any suggestions?
 
Carrotcake

Carrotcake

Experienced
Nov 27, 2019
265
Paracetamol is described to be toxic beginning at 250 mg/kg body weight or 12g total according to this source https://patient.info/doctor/paracetamol-poisoning however, as is mentioned a lot on this site, paracetamol overdose is no fun. You will die a very slow and painful death or do irreversible damage if you survive.

Regarding amitryptiline, you need a minimum of 20mg/kg body weight, according to this source https://gpnotebook.com/simplepage.cfm?id=74121286
So you don't have enough now.

Combing paracetamol and ami is probably not going to duplicate so no extra lethal effect. Paracetamol—> liver, ami od—> cns depression (if I recall correctly).

I don't know a lot about oxy, but if you say you have a opioid tolerance, I doubt that it will give you any/enough effect on top of the other substances.
 
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JellyPenguin

Member
May 17, 2019
15
Damn I read 300mg ami would be enough and with oxy I tried 250mg before but it just caused me to be drowsy and drop my oxygen levels. So I thought a mixture would be good, with the paracetamol causing vomitting which I could aspirate and choke. Although now I'm thinking I might need to save more supply.
 
popcorn

popcorn

Experienced
Dec 20, 2020
298
i doubt it would work

defo swerve the paracetamol its not the way to go. if the others dont work you will die of renal failure which is excruciating, apparently
 

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