I assuming you refer to the kill triangle snipers use right?
Yes and no, I have seen several videos of people who shot their face off while there entire brain was intact even the frontal cortex but it could work, but they might have aimed mid face it probably will work better if aiming at the forehead.
I had considered myself using a Glock 9mm to aim at the T-zone through the eye like George Hennard did (I have his suicide picture too) but I I wouldn´t aim for the nose with a 9mm, snipers can use the whole T-Zone because of the bigger caliber and higher speed.