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flank

flank

genetic trash
Aug 31, 2020
40
what is the strongest central nervous system depressant drug that exists? Name more than one if you know.
 
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Mm80

Mm80

Enlightened
May 15, 2019
1,604
Barbiturates like pentobarbital are the strongest i think followed by benzos and alcohol.
 
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GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,728
Chloroform is strong.
 
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almost_dead

almost_dead

Arcanist
Aug 7, 2020
465
Cyanide





(it's a joke)
 
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Mm80

Mm80

Enlightened
May 15, 2019
1,604
Love.
 
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GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,728
Is there something you are trying to tell us gpe ? That post really glowed btw

1. I'm trying to tell you an answer to OP's question.

2.
 
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M

mapletree

Student
Aug 22, 2020
199
Baseball bat to the head?
 
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A

Aap

Enlightened
Apr 26, 2020
1,856
Your question is impossibly vague. What are you considering a cns depressant? Something that can cause death? Anesthesia? What? How are you measuring it? Potency? Efficacy? The answers are different. Barbiturates are not very potent compared to say benzos but are far more efficacious.
 
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H

Homecoming

Wizard
Aug 14, 2020
644
Fentanyl or even the more potent and powerful Carfentanil :ohhhh:
 
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flank

flank

genetic trash
Aug 31, 2020
40
Your question is impossibly vague. What are you considering a cns depressant? Something that can cause death? Anesthesia? What? How are you measuring it? Potency? Efficacy? The answers are different. Barbiturates are not very potent compared to say benzos but are far more efficacious.
I want a strong CNS depressant that cause guaranteed death when combined with strong alcohol. DeathStar42 gave an incredible response citing carfentanil, but that is impossible to achieve.
 
A

Aap

Enlightened
Apr 26, 2020
1,856
If not including IV only medication, barbiturates and stronger opioids (full mu agonists) alone without Tylenol ( oxycodone, morphine, hydromorphone, heroin, fentanyl, sufentil, etorphine, and carfentanil). Potentially also ghb/gbl 2m2b

other Agents such as SN, amitriptyline, chloroquine, etc are not cns depressants in a meaningful sense.
 
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flank

flank

genetic trash
Aug 31, 2020
40
If not including IV only medication, barbiturates and stronger opioids (full mu agonists) alone without Tylenol ( oxycodone, morphine, hydromorphone, heroin, fentanyl, sufentil, etorphine, and carfentanil).

other Agents such as SN, amitriptyline, chloroquine, etc are not cns depressants in a meaningful sense.
in your opinion which is the best to use with alcohol, phenobarbital or rohypnol (flunitrazepam)?
 
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A

Aap

Enlightened
Apr 26, 2020
1,856
Phenobarbital can cause death in high doses, though it can take quite a while of not being discovered. Flunitrazepam cannot alone and likely not even with alcohol in most circumstances.
 
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Life_and_Death

Life_and_Death

Do what's best for you 🕯️ Sometimes I'm stressed
Jul 1, 2020
6,745
DeathStar42 gave an incredible response citing carfentanil, but that is impossible to achieve.
This was my original plan. Did you check the darkweb?
 
M

MariV

Arcanist
Sep 13, 2020
487
GHB is pretty strong and ypu can buy it legally and easily
 
grungeCat

grungeCat

Awkward & weird
Jul 5, 2020
1,110
Opioids. I've tried a lot of drugs yet nothing can be compared to the strength of opioids. The most crippling drugs ever. Opioids.
 
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A Retarded Demon

A Retarded Demon

Gib Pancakes Plz
Jul 9, 2020
41
Honestly it depends on you. Fluoxetine is the GP favourite with most it does nothing with others it puts their suicidal thinking on steroids and they do it the next day.
 
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mahakaliSS_MahaDurga

mahakaliSS_MahaDurga

Visionary
Apr 2, 2020
2,404
Honestly it depends on you. Fluoxetine is the GP favourite with most it does nothing with others it puts their suicidal thinking on steroids and they do it the next day.
Maybe I should be put back on it to find courage to finally do it.
 
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W

whywere

Visionary
Jun 26, 2020
2,746
well the strongest is ohmecarfentanil then it goes to Lofentanil, and then Carfentanyl and maybe a couple of the analog cousins, like sufentanil and thiofentanil amoung others, might be right up there.
 
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A

Aap

Enlightened
Apr 26, 2020
1,856
In before threads on sourcing lofentanil
 
W

whywere

Visionary
Jun 26, 2020
2,746
Generally Ohmecarfentanil is considered the strongest becasue of the time line that it stays effective. its durration is alot longer than Lofentanil or Carfentanil. But no matter what a human that would come in contact with any of it, without darn near instant reversal agent, one is dead. When they use this types of chemicals to tranquilize large animals they ALWAYS carry Narcan in case they come in contact with it.
 
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Bauhaus

Bauhaus

Specialist
Jan 18, 2020
388
In regard to benzos, the strongest I know is flubromazolam (only available on internet).
I once read a report of a guy who took 3mg (12 pills) and was in a coma for 1 or 2 days.
 

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