Vaughn
Experienced
- Feb 21, 2019
- 227
I have researched much the AMITRiPTyLINE COCKTAIL. version 2. if you know anything else or have experience with this cocktail - let the thread know. As some of you know of me 'Research is the key' - so add to this experience - thanks.
1) Amitriptyline 9 grams is the lethal component of the cocktail.
Tricyclic antidepressants (TCAs) exert their lethality mainly since they are sodium channel blockers.[1]
If the arrhythmia continues, blood circulation will cease, and death (as in, ventricular fibrillation) will occur in a matter of minutes.
2) Cimetidine 2.5 grams achieves two goals in the cocktail:
it hastens death;
3) Midazolam (Dormicum 300 mg) is quick acting and of short duration, while while
4) Diazepam (Valium) 300 mg) )is slower acting but of long duration; both are powerful sedatives from the benzodiazepine class of drugs. They cause deep sleep before amitriptyline starts to act in overdose. Amitriptyline poisoning would be lethal by itself, but the death it causes would not be peaceful.
How long does the cocktail take?[edit]
Since TCAs tend to slow the digestive process and absorption from the intestines, death would occur within 12-24 hours.
Oh, one must start off with the right anti-emetics...
Antiemetic regimen
It is very important to use drugs that prevent vomiting (i.e. antiemetic drugs) before one takes the cocktail. Some of the which work with the cocktail include:
1) Amitriptyline 9 grams is the lethal component of the cocktail.
Tricyclic antidepressants (TCAs) exert their lethality mainly since they are sodium channel blockers.[1]
If the arrhythmia continues, blood circulation will cease, and death (as in, ventricular fibrillation) will occur in a matter of minutes.
2) Cimetidine 2.5 grams achieves two goals in the cocktail:
it hastens death;
- it eliminates any possibility of survival and renders the cocktail much more lethal.
3) Midazolam (Dormicum 300 mg) is quick acting and of short duration, while while
4) Diazepam (Valium) 300 mg) )is slower acting but of long duration; both are powerful sedatives from the benzodiazepine class of drugs. They cause deep sleep before amitriptyline starts to act in overdose. Amitriptyline poisoning would be lethal by itself, but the death it causes would not be peaceful.
How long does the cocktail take?[edit]
Since TCAs tend to slow the digestive process and absorption from the intestines, death would occur within 12-24 hours.
Oh, one must start off with the right anti-emetics...
Antiemetic regimen
It is very important to use drugs that prevent vomiting (i.e. antiemetic drugs) before one takes the cocktail. Some of the which work with the cocktail include:
- Prochlorperazine - this is the most potent dopamine blocker.
- Metoclopramide
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