Sodium Nitrite without anti sickness tablets

[1234dave]

Sodium Nitrite without anti sickness tablets, is this possible?

 

[Raggas]

Possible? Yes. Worth it? No.

 

[1234dave]

Have people done it without?

 

[Meretlein]

The PPH says it's possible. If you can't get meto, I would get some OTC dramamine as an antiemetic.

 

[KnightOfEnceladus]

Dramamine, IIRC, is just Benadryl with some chlorinated derivative of theophylline in it to counteract some of the sleepiness: https://en.wikipedia.org/wiki/Dimenhydrinate

So it may be more cost-effective to just get whatever's cheaper. Just keep in mind, overdoses of diphenhydramine are extremely unpleasant, e.g. https://en.wikipedia.org/wiki/Diphenhydramine#Overdose

I would suggest using no more than 6 doses at once, and only as a partial, very weak anti-nausea med. The problem, of course, is that diphenhydramine itself can cause vomiting...

 

[1234dave]

There has been users on here that have done it without I think..

 

[fisil]

There has been users on here that have done it without I think..

You just answered your oven question. Eden2k survived without

 

[1234dave]

You just answered your oven question. Eden2k survived without

Yes but what about the guy that took it at the river and he showed pictures of his sick? Did he die? I don't think he used any?

I suffer with akathisia and scared the anti sickness will trigger it

 

[NextSummer]

You mean him: https://sanctioned-suicide.net/threads/took-sn-heres-my-story.15395/page-3#post-302495

He seems to have put SN in capsules. Don't know, sounds risky

 

[Soul]

I think I'll have two or three doses of SN at hand to drink (one at a time) if I start hurling.

 

[1234dave]

I think I'll have two or three doses of SN at hand to drink (one at a time) if I start hurling.

Are you using anti sickness?

 

[DetachedDreamer97]

The PPH says it's possible. If you can't get meto, I would get some OTC dramamine as an antiemetic.

Scopolamine Butylbromide or Datura Inoxia would be more ideal.

 

[stillwoozy]

I wouldn't do it. You may succeed, but my guess is it would be even more agonizing. You may also fail, the only time I have heard of people failing at SN is when they don't dose properly and/or don't take meto.

You can get meto online pretty easily. Worst case, it doesn't come through because you don't have a prescription. I'm not sure how legit it is, but there are online pharmacies were you can get a "prescription" for meto for migraine treatment? Regardless, I have never heard of anyone getting in legal trouble over ordering anti-nausea tablets online

 

[Meretlein]

Scopolamine Butylbromide or Datura Inoxia would be more ideal.

Can you explain?

 

[KnightOfEnceladus]

Scopolamine sounds like an odd choice for this, as it's a powerful anticholinergic agent; an antimuscarinic, specifically. Wiki article says it stops vomiting because, although it doesn't cross the blood/brain barrier very well, it does a little bit in the lower regions which affects vomiting. Datura spp. are natural sources of the same kind of tropamine alkaloids.

 

[Soul]

Are you using anti sickness?

Assuming I go with SN I will try to get anti-emetics, yeah. But I still think I'll have another dose or two of SN ready just in case.

 

[DetachedDreamer97]

Can you explain?

Besides motion sickness, it directly prevents your stomach and intestines from contracting by blocking the stimulus, thus preventing diarrhea and vomiting. Butylbromide is less likely to cross the blood brain barrier. While for datura inoxia, you have scopolamine and hyoscyamine. Which will effect both.

 

[Halo13]

You mean him: https://sanctioned-suicide.net/threads/took-sn-heres-my-story.15395/page-3#post-302495

He seems to have put SN in capsules. Don't know, sounds risky

His entire thread is here. Personally, I thought he succeeded.

https://sanctioned-suicide.net/threads/my-final-day-on-this-earth.15917/#post-304362

 

[Meretlein]

Besides motion sickness, it directly prevents your stomach and intestines from contracting by blocking the stimulus, thus preventing diarrhea and vomiting. Butylbromide is less likely to cross the blood brain barrier. While for datura inoxia, you have scopolamine and hyoscyamine. Which will effect both.

You seem pretty smart. How do you know this?

 

[Karangel25]

You just answered your oven question. Eden2k survived without

He survived the attempt without meto ?
Would this work as an antiemetic?

 

[mattwitt]

He survived the attempt without meto ?
Would this work as an antiemetic?

Nobody knows for sure but you can find the same active ingredient in Dramamine 2 the "less drowsy" version.

 

[KnightOfEnceladus]

@Karangel25: likely not. Dramamine and such only suppress vomiting because they, like the antimuscarinics nixonnate mentioned, exert anticholinergic effects. It's rather weaker in their case though. You really do need a dopamine D2 or serotonin 5HTP-3 antagonist for assured success. Metoclopramide/Reglan is the archetypical dopamine D2 blocker and ondansetron/Zofran the textbook 5THP-3 antagonist for anti-nausea effects. And they're prescription only ><

 

[Karangel25]

I just ordered some it was supposed to be here but I missed the carrier. Have to call tomorrow.

 

[mattwitt]

@Karangel25: likely not. Dramamine and such only suppress vomiting because they, like the antimuscarinics nixonnate mentioned, exert anticholinergic effects. It's rather weaker in their case though. You really do need a dopamine D2 or serotonin 5HTP-3 antagonist for assured success. Metoclopramide/Reglan is the archetypical dopamine D2 blocker and ondansetron/Zofran the textbook 5THP-3 antagonist for anti-nausea effects. And they're prescription only ><

Dramamine 2 the "less drowsy" version has Meclizine in it which is a dopamine D1 and D2 blocker.

This is from Wiki...

Mechanism of action[edit]
Meclizine is an antagonist at H1 receptors. It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Its antiemetic and antivertigo effects are not fully understood, but its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone.[18] Meclizine also is a dopamine antagonist at D1-like and D2-like receptors[citation needed] but does not cause catalepsy[note 1] in mice, perhaps because of its anticholinergic activity.[19]

 

[Karangel25]

Dramamine 2 the "less drowsy" version has Meclizine in it which is a dopamine D1 and D2 blocker.

This is from Wiki...

Mechanism of action[edit]
Meclizine is an antagonist at H1 receptors. It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Its antiemetic and antivertigo effects are not fully understood, but its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone.[18] Meclizine also is a dopamine antagonist at D1-like and D2-like receptors[citation needed] but does not cause catalepsy[note 1] in mice, perhaps because of its anticholinergic activity.[19]

So you think it will work? It's worth a shot trying.

 

[mattwitt]

So you think it will work? It's worth a shot trying.

I don't know. As far as I know nobody on this site has ever tried Meclizine with SN and reported back what happened. It's the only otc anti e I was ever able to find that has dopamine blockers.

 

[DetachedDreamer97]

You seem pretty smart. How do you know this?

I spent months obsessively researching on a cocktail where I needed a specific type of antiemetic for it and found scopolamine. Then I researched that.

 

[AhG]

Truthfully I have my SN and I've wondered if I should use meds or not. I'm still debating so we'll see.

 

[GeorgeJL]

You can still get zantac and a proton pump inhibitor like omeprazole AKA Prilosec over the counter at your local pharmacy. Those would go a long way. For omeprazole you would have to start taking it a few days before hand.

 

[jake3d]

They say PPIs are a no go, am i wrong on this? But Zantac should work, indeed.