Roger
I Liked Ike
- May 11, 2019
- 972
People have mentioned making SN filled capsules, and I think it's something worth exploring.
Presumably the point is to avoid the unpleasantness of downing a very salty drink ?
Does that mean that the vomit reflex is suppressed partially or wholly if SN is ingested via capsules ? I mean, is the gagging reflex prompted by the taste buds, or by something in the stomach ?
How long do normal capsules take to dissolve, releasing the SN into the digestive tract ? This seems important, as the timing of taking antiemetic and antacids followed by the SN dose appears crucial.
If the gelatin capsules are dissolved by acidity in the stomach, I wonder whether the effect of antacids (ranitidine in my case) would slow down the dissolution of the capsules.
SN appears to consist of quite large crystals. This isn't a problem when it is taken in solution as it dissolves readily, but when packed into capsules it will not be anywhere near as dense as the fine powders one normally sees in capsules. The upshot is - presumably - that an awful lot of capsules would need to be made and taken. I don't think that you can say that a given size capsule holds a given weight of filling.
I see that there are inexpensive capsule filling "machines" on the market for small scale use (between 30 and 100 capsules at a time.) These should ensure reasonable weight/volume consistency per capsule, as opposed to hand filling. I envisage weighing out the required SN dose (I'm looking at 25 gm) and pouring this into the feed tray of the machine.
I would still take antiemetics and antacids as per normal - capsules would be a further enhancement.
Anyway, it's a new idea for me, and I have no knowledge - I'm just hoping to stimulate some productive discussion.
Presumably the point is to avoid the unpleasantness of downing a very salty drink ?
Does that mean that the vomit reflex is suppressed partially or wholly if SN is ingested via capsules ? I mean, is the gagging reflex prompted by the taste buds, or by something in the stomach ?
How long do normal capsules take to dissolve, releasing the SN into the digestive tract ? This seems important, as the timing of taking antiemetic and antacids followed by the SN dose appears crucial.
If the gelatin capsules are dissolved by acidity in the stomach, I wonder whether the effect of antacids (ranitidine in my case) would slow down the dissolution of the capsules.
SN appears to consist of quite large crystals. This isn't a problem when it is taken in solution as it dissolves readily, but when packed into capsules it will not be anywhere near as dense as the fine powders one normally sees in capsules. The upshot is - presumably - that an awful lot of capsules would need to be made and taken. I don't think that you can say that a given size capsule holds a given weight of filling.
I see that there are inexpensive capsule filling "machines" on the market for small scale use (between 30 and 100 capsules at a time.) These should ensure reasonable weight/volume consistency per capsule, as opposed to hand filling. I envisage weighing out the required SN dose (I'm looking at 25 gm) and pouring this into the feed tray of the machine.
I would still take antiemetics and antacids as per normal - capsules would be a further enhancement.
Anyway, it's a new idea for me, and I have no knowledge - I'm just hoping to stimulate some productive discussion.