ב''ה,
As this has been a matter of contemplation:
It's not rational, but the heart thing.. maybe we've got such instinct to protect the head or something, a few extra moments of pain to avoid a millisecond of the idea of headache, I don't know.
Rationally, just go for the brainstem.
Outside of that, in the G-d knows what any of us are ever going to do mode of it all:
If going for the heart, and hopefully not just winging it or having it at least half close up for a minute or more of agony because the body can do weird shit:
1. Be prepared for the slump. Haven't gone out of my way to see videos, but if accurately placed going down like a sack of potatoes is a thing and if hitting the head sounds unpleasant, you might be conscious long enough to feel yourself smacking your head or nose on the floor anyway.
2. Assuming anything about "1" is possible, having your mind prepared to somehow hang onto the gun and pop one into the mouth if things are taking more than 45 seconds might be a good idea. G-d knows whether that's possible or necessary, just seems like an "under these circumstances," consideration that might spare suffering if anything goes wrong.
This is a lot more bullets than no bullets, so, y'know, that's potentially two bullets that could cause further calamity in the world, so everyone else would probably appreciate this not being from a top floor apartment or such, if, say, doing it laying down to not reckon with the slump.
Not much of a gun nut but the apparent success kind of braced off a desk for proper placement but of course fell sort of down and over from the partial squat that entailed. Probably dropping the gun. So technically having some kind of grip that keeps it at hand if a minute goes by and 'oh fuck, I only hit a lung' somehow happens and the wherewithal stays with for all this.. we're fucking tired of yet more suffering, right?
Just stuff to keep in mind. Genuinely not sure how much harder good positioning from a laying down position would be, it does seem weird somehow maybe just for some primal going out standing before G-d kind of thing, huh.
Good Shabbos.