Prepping, does this plan look ok?

[Notforlong]

Just going through the finals stages of prepping. I read the 2022 ed of the PPH and this is the plan so far:

- Fast 12 hours
- 1 hour before
100mg of dimenhydrinate
80mg esomeprazole
2mg etizolam
- Drink SN

Unfortunately I don't have access to a stronger AE, but PPH says Dimenhydrinate is fine. I CAN, however, pick up some propranolol but I'm not sure it's necessary. I do also have some extremely potent designer benzos that I could fit in somewhere. At first I was thinking of taking them after then SN but they would cause me to black out almost instantly unless I took a very small dose. Should I look for a stronger AE and grab the propranolol?

 

[jodes2]

Stronger AE is highly recommended. A combination like ondansetron and domperidone is a great one, used for cancer patients. Propranolol will reduce the suffering but apparently you shouldn't use too high a dose

 

[hapiniuier]

You might want to read this regarding esomeprazole:

Blood Pressure-Lowering Effect of Orally Ingested Nitrite Is Abolished by a Proton Pump Inhibitor - PubMed

Inorganic nitrate and nitrite from dietary and endogenous sources are metabolized to NO and other bioactive nitrogen oxides that affect blood pressure. The mechanisms for nitrite bioactivation are unclear, but recent studies in rodents suggest that gastric acidity may influence the systemic...

pubmed.ncbi.nlm.nih.gov

Commentary on “The blood pressure-lowering effect of orally ingested nitrite is abolished by a proton pump inhibitor” by M. F. Montenegro et al

www.ncbi.nlm.nih.gov

 

[Notforlong]

You might want to read this regarding esomeprazole:

Blood Pressure-Lowering Effect of Orally Ingested Nitrite Is Abolished by a Proton Pump Inhibitor - PubMed

Inorganic nitrate and nitrite from dietary and endogenous sources are metabolized to NO and other bioactive nitrogen oxides that affect blood pressure. The mechanisms for nitrite bioactivation are unclear, but recent studies in rodents suggest that gastric acidity may influence the systemic...

pubmed.ncbi.nlm.nih.gov

Commentary on “The blood pressure-lowering effect of orally ingested nitrite is abolished by a proton pump inhibitor” by M. F. Montenegro et al

www.ncbi.nlm.nih.gov

Interesting, the PPH explicitly mentions Esomeprazole in conjunction with SN.

 

[hapiniuier]

Interesting, the PPH explicitly mentions Esomeprazole in conjunction with SN.

Not anymore.

PPH Essentials 2022

https://bunkrr.su/d/STZOEANPJhEjC [link has no preview] Edit: August 2023, fixed the links.

sanctioned-suicide.net

 

[Notforlong]

Not anymore.

PPH Essentials 2022

https://bunkrr.su/d/STZOEANPJhEjC [link has no preview] Edit: August 2023, fixed the links.

sanctioned-suicide.net

This is strange, I have the PPH eHandbook which has a publication date of 2022. This one is the essentials edition which is indeed different but also looks to be published in 2022. Strangely enough, the version I have has a note that says "some reports mistakenly claim that acid reduction is counterproductive as it reduces NO release".