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LittleJem

Visionary
Jul 3, 2019
2,600
Does anyone have thoughts on the following? I am choosing between 3 options for my next medication:

Option 1: olanzapine+fluoextine - there are some great reviews, but I am scared of gaining lots of weight and withdrawals sound so hideous. People have been telling me it isn't always that bad...I'm worried I will be sedated and zombie like and the effects will be permanent, like permanent insomnia can be a withdrawal effect etc...

Option 2: Wellbrutin/Lexapro - this seems like a good combo. If the side effects are horrible I think it is easier to come off than the Olanzapine/fluoextine. It says it helps maybe 50% of people to get remission

Option 3: Lamictal - there are some miracle reviews for depression for this online. I guess this could also be added to option 2.

Background info:

The first option is prescribed by a psychiatrist but I am nervous of it as it feels irreversible. I don't like or trust psychiatrists and would rather have a choice of medication. But if I do take my own choice of medication and get terrible side effects, I'll be blamed for it. But if I take their medication and get huge weight gain and worse depression, permanent insomnia etc. I will have to live with it....Is this pathetic? I know lots of people take this medication...

No working diagnosis. Let's say anxiety/depression or bipolar depression if that exists. When I was younger I had weird crushes on people alongside the depression and would be reacting to things internally but faking it on the outside - always anxious/agitated but faking it. I think that is some kind of autism maybe, I never felt connected to people and didn't understand small talk. Also childhood trauma. Then I think the trauma led me to believe in a load of new age stuff which at the time was real, and now I don't believe in anymore. At the moment SI and agitated all day long, really grumpy and not social, not able to get out of bed without edibles. Crying and calling suicide hotlines. Can't afford edibles and they make me somewhat mad. Think about CTB all day every day and no quality of life.

I wonder if I'm mad but say option 2 makes me happier, will I be more mad. I'm sorry for using the word mad, but looking back on my life now I am trying to come to terms with how much of it has been me being mad...So does option 1 make me less mad. I thikn the main thing I want is not to feel suicidal all the time and to be able to get out of bed and function. If I could laugh that would be amazing. I haven't laughed for years.

I know they will all have side effects and I am a big wuss. I just hate the idea of extra agitation, insomnia, constipation or the reverse. I know that's all part of trying these things and am kind of sticking with this so I don't upset people by CTB, but I am also going to have my CTB at the ready before I start any new med. My worst fear is being bedridden without the means to CTB.
 
september

september

Apr 15, 2023
19
Option 2 is likely your safest bet, but as you should know medication differs for everyone. Have heard a lot of good things about Lamictal as well, but after a negative experience with Lithium I have tried to steer clear of things similar. Wellbutrin is extremely easy to get off of, have quit it cold turkey twice now, albeit YMMV.

For Option 1, what you wrote is roughly the same thing I'd say too. I recently had this combination and it made me feel worse and increased my self destructive tendencies, but both medications here are more "hit and miss" than the others. I know someone who is taking the same combo and it has made their quality of life much better, but either way the withdrawals of these two are worse.

All in all, its just a game of finding which "medicinal cocktail" works for you. Trial and error is unfortunately a part of this and for many people they spend a longggg time trying to figure out what truly helps them without long term damage.
 
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bijou

bijou

meow meow meow
Jan 23, 2023
173
i've taken olanzapine+ssri, not a fan! i've also taken wellbutrin+ssri, was a big fan, i am desperately trying to get back on this combination! i struggled a lot with productivity and focus, this combination is sometimes used off-label for inattentive-adhd. the sexual side-effects of the ssri were also canceled out by the wellbutrin.

olanzapine, however, will probably not make you a "zombie" if taken as prescribed. it will make you very drowsy, and very very hungry. it is sometimes prescribed off-label for insomnia, as are many other antipsychotics.