For me, it is the constant barrage of shitty life (it may/not apply to everyone as everyone's lives are different, tolerances, and views vary), and personal suicide fuel. My personal suicide fuel is the realization of the problems that I cannot solve, the incurable conditions (social anxiety throughout my life, constant situational depression (comes and goes but very frequently due to shitty life), Aspergers (currently no cure) which totally fucks up my social life as well as social interaction between people which apparently is one of the most important things in getting around in life.), the unjust world, the hypocrisy of others (especially the pro-life, anti-suicide people, and religious people who use illogical reasoning, etc.), and of course, wage slavery until you become old, your body fails, and then death.