The lethal dose of nicotine for adults has been
known as 40
-
60 mg (0.5
-
1.0 mg/kg body weight).
Fatalities have been reported from ingestion of 30 g
tobacco and 0.8 g of snuff. Nicotine poisoning by oral
self-administration or intravenous injection of nicotine
solution or nicotine liquid used in e-cigarettes,
applying transdermal nicotine patches, ingestion of
nicotine pesticides, excessive smoking were reported,
as well as accidental swallowing or ingestion of
tobacco or tobacco products by children, ingestion of
salads containing wild tobacco, boiled tobacco water
enemas for intestinal parasites, or toxic dermal
absorption of tobacco harvesters.
1
-
3,6)