Metoclopramide and anti-psychotics

[UnlockTheShrine]

Hello, I want to ask if I can take metoclopramide with anti-psychotics? I have to take them, no way around that. Will it make a big problem following that 48 regime with metoclopramide while I am on anti-psychotics?

 

[Superfluous]

I don't think the issue is taking the meto with anti-psychotics but rather the effectiveness of the active drug(s) used to end life.

Wikibooks: Anti-emetic regimen link

The following advice comes from Dr Nitschke and other sources:

• Tolerance to alcohol, benzodiazepines, analgesics, prolonged use of anti-psychotics, and gastrointestinal issues can complicate overdosing. It is advisable that medications that can be stopped (without affecting judgment), should be ceased a few weeks prior to the drug ingestion, as should alcohol and narcotics consumption.

If you could let us know your drug of choice, then we may be able to provide a more detailed answer.

 

[UnlockTheShrine]

I don't think the issue is taking the meto with anti-psychotics but rather the effectiveness of the active drug(s) used to end life.

Wikibooks: Anti-emetic regimen link



If you could let us know your drug of choice, then we may be able to provide a more detailed answer.

I'm taking olanzapine, primperan is anti-emetic that I want to use.

 

[Superfluous]

I should first say that I am not a medical professional.

I apologise if I'm coming across as a bit anal, but I would also like to clarify with you the reason for needing to take an anti-emetic regimen. Is it to help with a preexisting condition, or Is it for the purpose of preventing vomiting as a result of subsequently taking a lethal dose of drugs to end your life? If it is the latter, could you specify which method: Nembutal, SN, Amitriptyline cocktail, DDMP cocktail...

I have checked the interactions between olanzapine and meto and came across this article on WebMD. I believe this source to be reliable. There is a medical warning at the very start of the article:

Serious. These medicines may interact and cause very harmful effects

As such, I could not recommend taking meto with olanzapine.

Having investigated a bit further, I found the following article that states that olanzapine itself has anti-emetic properties:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093458/

I'm not sure how much further advice I can provide. Maybe others on this forum with better medical knowledge can assist.

 

[jayfox]

I should first say that I am not a medical professional.

I apologise if I'm coming across as a bit anal, but I would also like to clarify with you the reason for needing to take an anti-emetic regimen. Is it to help with a preexisting condition, or Is it for the purpose of preventing vomiting as a result of subsequently taking a lethal dose of drugs to end your life? If it is the latter, could you specify which method: Nembutal, SN, Amitriptyline cocktail, DDMP cocktail...

I have checked the interactions between olanzapine and meto and came across this article on WebMD. I believe this source to be reliable. There is a medical warning at the very start of the article:



As such, I could not recommend taking meto with olanzapine.

Having investigated a bit further, I found the following article that states that olanzapine itself has anti-emetic properties:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093458/

I'm not sure how much further advice I can provide. Maybe others on this forum with better medical knowledge can assist.

Meto and antipsychotics don't mix:

Drug Interaction Report: metoclopramide, olanzapine

View detailed report of drug-drug and drug-food interactions for metoclopramide, olanzapine

www.drugs.com

I also take olanzapine you have to do the stat regiment instead of 48h or do 36h sleep without taking it and Ctb the next day , that's how I think I'm going to do it the interactions are bad

 

[Sweetrelease]

Would Zofran work as well as meto? I also have been on a low dose of AP for sleep...Looking to use with N

 

[jayfox]

Would Zofran work as well as meto? I also have been on a low dose of AP for sleep...Looking to use with N

You need meto. No other way around it.

 

[Sweetrelease]

You need meto. No other way around it.

I guess I'll discontinue the AP for awhile and hope for the best :/

 

[Bilbobaggins]

I'm on aripiprazole 10mg OD. Would that interfere with the taking of meto for 48h prior to SN?

 

[JadedGray]

Would Zofran work as well as meto? I also have been on a low dose of AP for sleep...Looking to use with N

Yes, you could use Zofran according to this thread: https://sanctioned-suicide.net/threads/anti-emetics-reglan-vs-zofran.14609/

 

[Raggas]

I should first say that I am not a medical professional.

I apologise if I'm coming across as a bit anal, but I would also like to clarify with you the reason for needing to take an anti-emetic regimen. Is it to help with a preexisting condition, or Is it for the purpose of preventing vomiting as a result of subsequently taking a lethal dose of drugs to end your life? If it is the latter, could you specify which method: Nembutal, SN, Amitriptyline cocktail, DDMP cocktail...

I have checked the interactions between olanzapine and meto and came across this article on WebMD. I believe this source to be reliable. There is a medical warning at the very start of the article:



As such, I could not recommend taking meto with olanzapine.

Having investigated a bit further, I found the following article that states that olanzapine itself has anti-emetic properties:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093458/

I'm not sure how much further advice I can provide. Maybe others on this forum with better medical knowledge can assist.

Would I be at risk if I wanted to use a stat dose of meto for SN, if I had monthly paliperidone injections?

 

[UnlockTheShrine]

I should first say that I am not a medical professional.

I apologise if I'm coming across as a bit anal, but I would also like to clarify with you the reason for needing to take an anti-emetic regimen. Is it to help with a preexisting condition, or Is it for the purpose of preventing vomiting as a result of subsequently taking a lethal dose of drugs to end your life? If it is the latter, could you specify which method: Nembutal, SN, Amitriptyline cocktail, DDMP cocktail...

I have checked the interactions between olanzapine and meto and came across this article on WebMD. I believe this source to be reliable. There is a medical warning at the very start of the article:



As such, I could not recommend taking meto with olanzapine.

Having investigated a bit further, I found the following article that states that olanzapine itself has anti-emetic properties:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093458/

I'm not sure how much further advice I can provide. Maybe others on this forum with better medical knowledge can assist.

preventing vomiting, SN. I guess I will discontinue the olanzapine. but it will take at least a year for me to do that...

 

[Ruffian]

I should first say that I am not a medical professional.

I apologise if I'm coming across as a bit anal, but I would also like to clarify with you the reason for needing to take an anti-emetic regimen. Is it to help with a preexisting condition, or Is it for the purpose of preventing vomiting as a result of subsequently taking a lethal dose of drugs to end your life? If it is the latter, could you specify which method: Nembutal, SN, Amitriptyline cocktail, DDMP cocktail...

I have checked the interactions between olanzapine and meto and came across this article on WebMD. I believe this source to be reliable. There is a medical warning at the very start of the article:



As such, I could not recommend taking meto with olanzapine.

Having investigated a bit further, I found the following article that states that olanzapine itself has anti-emetic properties:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093458/

I'm not sure how much further advice I can provide. Maybe others on this forum with better medical knowledge can assist.

I'm not surprised by this. Antipsychotics and meto all share similar profiles. I was on Stelazine as an anti psychotic and it has ant-emetic properties.

 

[Meretlein]

Zyprexa is used as an antiemetic. However antipsychotics are not compatible with N.

 

[Sweetrelease]

Zyprexa is used as an antiemetic. However antipsychotics are not compatible with N.

If I cease my antipsychotic for a few weeks do you think my N attempt will be successful?

 

[Meretlein]

If I cease my antipsychotic for a few weeks do you think my N attempt will be successful?

Yes.

 

[Peacelove44]

I take 10mg Escitalopram (seroplex) and 20mg olanzapine (zyprexa). How shall I proceed if I want to ctb with N?

 

[dolphin]

I feel like everyone should try to discontinue all meds at least a few weeks in advance. If you are on antipsychotics, you definitely need to discontinue if you plan on taking antiemetics because they are both anti-dopaminergic so you could potentially end up with severe side effects and this will affect your plan.

 

[Peacelove44]

I feel like everyone should try to discontinue all meds at least a few weeks in advance. If you are on antipsychotics, you definitely need to discontinue if you plan on taking antiemetics because they are both anti-dopaminergic so you could potentially end up with severe side effects and this will affect your plan.

Ty for reply. What about antidepressant?

I feel like everyone should try to discontinue all meds at least a few weeks in advance. If you are on antipsychotics, you definitely need to discontinue if you plan on taking antiemetics because they are both anti-dopaminergic so you could potentially end up with severe side effects and this will affect your plan.

By the way do you know how to get antiemetic?

 

[dolphin]

Ty for reply. What about antidepressant?

By the way do you know how to get antiemetic?

I would stop taking it. I checked for interactions between zoloft (an antidepressant - not sure what you are taking) - and meto and it can increase the risk of serotonin syndrome.

I would stop taking it. I checked for interactions between zoloft (an antidepressant - not sure what you are taking) - and meto and it can increase the risk of serotonin syndrome.

I ordered off of bonanza. They have some on alldaychemist.com. What is available to you depends on where you are from.

 

[Peacelove44]

I would stop taking it. I checked for interactions between zoloft (an antidepressant - not sure what you are taking) - and meto and it can increase the risk of serotonin syndrome.


I ordered off of bonanza. They have some on alldaychemist.com. What is available to you depends on where you are from.

Ty for your answer. I am from France. I don't know where to buy some =(.

 

[Allpainnogain]

Ugh so even with N I could fail....I'm on 6 medications...feel so hopeless and trapped. Why don't I die in my sleep...I am so desperate!!!!!!

 

[Peacelove44]

A proposed me some antiemetic. How long shall I stop medication before being able to safely take the antiemetics?

 

[chrijo]

I take 10mg Escitalopram (seroplex) and 20mg olanzapine (zyprexa). How shall I proceed if I want to ctb with N?

Hi peacelove :-)

Olanzapine can enhance the antiemetic effect of other antiemetics, there's no need to stop taking Zyprexa. Escitalopram itself can cause vomiting because of an elevated serotonin level. It is your decision to stop it.

 

[jayfox]

Hi peacelove :-)

Olanzapine can enhance the antiemetic effect of other antiemetics, there's no need to stop taking Zyprexa. Escitalopram itself can cause vomiting because of an elevated serotonin level. It is your decision to stop it.

Olanzapine with meto can give you Parkinson like symptoms and disease

That's why when my time comes I'll do meto stat dose only and not the regimen

Drug Interaction Report: metoclopramide, olanzapine

View detailed report of drug-drug and drug-food interactions for metoclopramide, olanzapine

www.drugs.com

 

[Deadgirl]

What would topamax do with N? It's a anti convulsant

 

[chrijo]

Olanzapine with meto can give you Parkinson like symptoms and disease

That's why when my time comes I'll do meto stat dose only and not the regimen

Hi @jayfox

If you get extrapyramidal side effects, then most likely from meto. Olanzapine counts as safer. With the recommended stat dosage you also have a higher risk of getting EPS. Some people can't handle 40mg meto at once.

What would topamax do with N? It's a anti convulsant

It increases the activity of GABA A receptors. This means - N can act faster.

 

[Peacelove44]

Hi peacelove :-)

Olanzapine can enhance the antiemetic effect of other antiemetics, there's no need to stop taking Zyprexa. Escitalopram itself can cause vomiting because of an elevated serotonin level. It is your decision to stop it.

Ty for your answer. I would love to stop these meds but my mind is so fucked up. I am been in psychiatric hospital and they gave me valium which totally unbalance my stress regulation system. I am basically in permanent panic attack which sucks... I want to ctb asap. Don't know if I will be able to carry on until I get my N...

Hi @jayfox

If you get extrapyramidal side effects, then most likely from meto. Olanzapine counts as safer. With the recommended stat dosage you also have a higher risk of getting EPS. Some people can't handle 40mg meto at once.


It increases the activity of GABA A receptors. This means - N can act faster.

What is EPS?

 

[chrijo]

EPS = extrapyramidal symptoms.

These unpleasant symptoms have many people here, especially with high-dose metoclopramide.

But what I wanted to tell you here is that you can use zyprexa as antiemetic. It is also used as antiemetic in chemotherapy combined with zofran. It blocks serotonin and dopamin like meto do it. Both drugs are neuroleptics.

 

[Peacelove44]

EPS = extrapyramidal symptoms.

These unpleasant symptoms have many people here, especially with high-dose metoclopramide.

But what I wanted to tell you here is that you can use zyprexa as antiemetic. It is also used as antiemetic in chemotherapy combined with zofran. It blocks serotonin and dopamin like meto do it. Both drugs are neuroleptics.

How shall I proceed then? Taking my regular dose would be enough? Do you think zyprexa itself would be enough not to puke? Sadly I am afraid to stop taking my anitdepressant as it can bring serious side effect...