I'm scared to take Meto

[br0kenMIND72]

I have Primperan (Metoclopramide Hydrochloride Monohydrate) and SN but today I started to read about possible side effects of Meto and to be honest I don't want to take it because I always asume that if something bad can happen, It will happen. What really scares me is "tardive dyskenisia" and EPS. Also I wanted to see how I will feel when I'll have SN by my side and I really started to question myself, "Do I really want to die?" etc. what mainly pushes me off is a fear that I won't succed and I'll deal myslef some critical damage and I really don't want that. Maybe that fear will be the fuel I need, maybe actually I don't want to CBT.

Also on my SN bottle is says it expires 05.2021 and I thought it can be stored 3 years but It seems in my case this is not true.

It is great that this forum exists and people can be open about something that I belive is known as taboo, so thank you!

 

[BizarreBazaar]

Also on my SN bottle is says it expires 05.2021 and I thought it can be stored 3 years but It seems in my case this is not true.

Those are always conservative. It will last much longer.

 

[nonamegirl]

I was precribed meto some years ago after an awful flu that made me unable to eat afterawards because food just made me nauseous. worked like a charm and no side effects.

 

[HadEnough1974]

I have Primperan (Metoclopramide Hydrochloride Monohydrate) and SN but today I started to read about possible side effects of Meto and to be honest I don't want to take it because I always asume that if something bad can happen, It will happen. What really scares me is "tardive dyskenisia" and EPS. Also I wanted to see how I will feel when I'll have SN by my side and I really started to question myself, "Do I really want to die?" etc. what mainly pushes me off is a fear that I won't succed and I'll deal myslef some critical damage and I really don't want that. Maybe that fear will be the fuel I need, maybe actually I don't want to CBT.

Also on my SN bottle is says it expires 05.2021 and I thought it can be stored 3 years but It seems in my case this is not true.

It is great that this forum exists and people can be open about something that I belive is known as taboo, so thank you!

Your clearly not ready and I think you know it too.

 

[Lifeiswildsuperwild]

Hey- drugs of any kind are scary. I understand.
I went through the whole regime the other weekend until the SN part.
I've never taken Meto before in my life. After taking the last 30mg and before that taking it 3 times a day for the past two days.

The side effect I really noticed the day after not CTB- I just kept moving around. I could sit but I just felt like I need to move my arms and legs and sometime around the evening that all went away.
I remember after taking the 30mg and then not taking the SN. I was like am I gonna die from taking so much- nah. It's more uncomfortable. But prolonged usage will definitely have different results.

 

[throwaway_2620]

I have Primperan (Metoclopramide Hydrochloride Monohydrate) and SN but today I started to read about possible side effects of Meto and to be honest I don't want to take it because I always assume that if something bad can happen, It will happen. What really scares me is "tardive dyskenisia" and EPS.

Here are a couple threads you might find practical.

Spoiler: POST 601756

https://sanctioned-suicide.net/threads/sn-resource-page.32633/

Spoiler: POST 517024

https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/

The second thread is an N guide rather than an SN one, but it contains practical information regarding meto. To reduce the risk of possible side effects, I'd advise you to do your research before experimenting with meto. Feel free to have a read in your own time.

 

[k75]

If it helps any, because of a medical condition, I've been prescribed to take Meto 3 times a day, every day, since the beginning of the year. I can't say you won't experience side effects, but I haven't. For the last 5 years, I've had to do this treatment off and on. Never had an issue with it. Taking it for the 48 hr regimen is way less risky than taking it daily like I do.

That said, I think based on your initial post you might not be ready. It's ok to take some time and really think about things before you act. Just because you have supplies and have talked about wanting to ctb doesn't mean you're obligated to right now, or at all.

 

[jgm63]

@br0kenMIND72 As others have said, perhaps you're not ready to proceed with any method....

However, just so you have the correct information....
As @throwaway_2620 states, I have a thread with some antiemetic stuff.
This post in particular has some useful info :

Spoiler: post-517024

https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/post-517024

Basically, EPS is not very common. Also you can test and build up, plus have diphenhydramine on standby to treat any symptoms.
For the SN method, most people seem to either "catch the bus", or recover without too many lasting after effects.
The latter seems to be when they are found too early, or call for an ambulance themselves.

PEACEFULNESS
I've read various accounts of people taking SN, from various sources.
The overall impression I get is that it is fairly peaceful.
I believe there will likely be some discomfort, but I don't believe the discomfort level is too high.
I have heard it described as being like a "bad hangover".
I believe people usually go unconscious after about 20 minutes.
Note : I can only state what I believe to be true, based on things I have read and things that have been posted by others. I cannot give guarantees.

RELIABILITY
Overall the method seems reliable. The successful cases heavily outweigh the failed cases.
Virtually all of the failed cases appear to be where people were found or called an ambulance themselves, or where the protocol (Stan's guide) was not followed very closely.
If you take good precautions to not be found, and have a certain amount of determination to undergo some discomfort without calling an ambulance, then the chance of success should be very high. Some members have vomited, but still been successful. In the cases where people vomited it doesn't appear they drank any more SN, yet they still appeared to succeed, although the recommendation is to have a couple of extra glasses ready, and to drink more in the event of vomiting.

 

[Rdc]

I have Primperan (Metoclopramide Hydrochloride Monohydrate) and SN but today I started to read about possible side effects of Meto and to be honest I don't want to take it because I always asume that if something bad can happen, It will happen. What really scares me is "tardive dyskenisia" and EPS. Also I wanted to see how I will feel when I'll have SN by my side and I really started to question myself, "Do I really want to die?" etc. what mainly pushes me off is a fear that I won't succed and I'll deal myslef some critical damage and I really don't want that. Maybe that fear will be the fuel I need, maybe actually I don't want to CBT.

Also on my SN bottle is says it expires 05.2021 and I thought it can be stored 3 years but It seems in my case this is not true.

It is great that this forum exists and people can be open about something that I belive is known as taboo, so thank you!

I feel the same exact way. I've been fearful of taking Meto because of the possibility of developing a 'movement disorder. I was going to try a meto 10mg tablet to see how I would react but then decided to hold off after coming across this. It looks like you can have a reaction even after a single dose.

Extrapyramidal side effects after metoclopramide administration in a post-anesthesia care unit -A case report-

Although the incidence of extrapyramidal reactions associated with metoclopramide has been reported to be approximately 0.2%, such reactions are rare in the anesthetic field. Several anesthetic adjuvants, including ondansetron and pregabalin, have also ...

www.ncbi.nlm.nih.gov

Here is another article that describes the side effects and the odds of reacting to meto. I'm surprised that the odds of developing akithisia is 10-25% as that seems pretty high.it does state that ithe odds appears to be lower when taking tablets vs injection.

Metoclopramide in the Treatment of Diabetic Gastroparesis - Page 8

www.medscape.com

I guess it really doesn't matter if your successful at ctb. I just wouldnt want to test it out or survive an attempt and then be stuck with eps.

 

[Jumper Geo]

I have Primperan (Metoclopramide Hydrochloride Monohydrate) and SN but today I started to read about possible side effects of Meto and to be honest I don't want to take it because I always asume that if something bad can happen, It will happen. What really scares me is "tardive dyskenisia" and EPS. Also I wanted to see how I will feel when I'll have SN by my side and I really started to question myself, "Do I really want to die?" etc. what mainly pushes me off is a fear that I won't succed and I'll deal myslef some critical damage and I really don't want that. Maybe that fear will be the fuel I need, maybe actually I don't want to CBT.

Also on my SN bottle is says it expires 05.2021 and I thought it can be stored 3 years but It seems in my case this is not true.

It is great that this forum exists and people can be open about something that I belive is known as taboo, so thank you!

Good question, it's quite funny I was so occupied concentrating on ctb I never considered if there would be any side effects from the preparation meds I was so busy and happy finding all the ingredients. The question is when we choose our ctb date and that time arrives if our SI is really strong and we don't go through with it, will we be left with horrendous side effects as I am here from the side effects from risperidon. I am trying to prepare myself but I have read a lot of messages where they have prepared properly but couldn't drink the SN. I wish there was a pill for courage.

Then again would these side effects kick in after taking them for just 48 hours ?

 

[k75]

Then again would these side effects kick in after taking them for just 48 hours ?

There is a risk, yes. But in my experience, it probably won't happen. Everyone reacts differently to drugs, so there's no real guarantee either way. Like I mentioned earlier, I have to take it 3 times a day. Each time, I do pause and wonder if I'll experience anything bad with this dose, but ultimately the benefits outweigh that chance.

 

[jgm63]

I feel the same exact way. I've been fearful of taking Meto because of the possibility of developing a 'movement disorder. I was going to try a meto 10mg tablet to see how I would react but then decided to hold off after coming across this. It looks like you can have a reaction even after a single dose.

Extrapyramidal side effects after metoclopramide administration in a post-anesthesia care unit -A case report-

Although the incidence of extrapyramidal reactions associated with metoclopramide has been reported to be approximately 0.2%, such reactions are rare in the anesthetic field. Several anesthetic adjuvants, including ondansetron and pregabalin, have also ...

www.ncbi.nlm.nih.gov

Here is another article that describes the side effects and the odds of reacting to meto. I'm surprised that the odds of developing akithisia is 10-25% as that seems pretty high.it does state that ithe odds appears to be lower when taking tablets vs injection.

Metoclopramide in the Treatment of Diabetic Gastroparesis - Page 8

www.medscape.com

I guess it really doesn't matter if your successful at ctb. I just wouldnt want to test it out or survive an attempt and then be stuck with eps.

"Metoclopramide-Induced Acute Dystonic Reaction: A Case Report" states : "Acute dystonic reactions, the most common type of extrapyramidal symptom associated with metoclopramide, occur in approximately 0.2% of patients (1 in 500) treated with 30 to 40 mg of metoclopramide per day."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261495/

As mentioned above, this post has some useful info :

Spoiler: post-517024

https://sanctioned-suicide.net/threads/n-protocol-regime-regimen-notes.27092/post-517024

EPS is not very common. You can test and build up, plus have diphenhydramine on standby to treat any symptoms.

 

[Goaway]

I took it for the first time today as a test. Sleepiness and maybe some sweats were about the only side effect.

 

[br0kenMIND72]

Thank You for all the responses I feel like "I don't want to live anymore" for a very long time but I always said to myself "You will do this in the future". I think I need one or two weeks to prepare myself for this. Looking at my past - every my decision was based on my thought "It doen't concern me because I'm going to suicde". My real fear is that I will fail and not die, but If I'll succeed I will welcome death with my open arms. I still need to clean my room and prepare for this.
I assure you, I feel this way since childhood and I belive that end is near. Before I discovered this forum I wanted to die from hypothermia but this winter wasn't even cold.

I just want to say that this forum isn't bad, people should not even consider killing themselfs, it only shows how bad this world is and how bad some people are. What happens in mind of child? When it feels so much pain, so much suffering? My heart goes to all these kids that are suffering from alcoholic parents or maybe just bad parents or even no parents at all. I still feel like this little child, I don't want to be part of this world, I don't want to suffer anymore.
Once again big Thank You for being here

 

[Quarky00]

the odds of developing akithisia is 10-25% as that seems pretty high. it does state that ithe odds appears to be lower when taking tablets vs injection.

Seriously , comparing pills with direct IV of metoclopramide ?

Let's stop the hysteria.

Meto has risks (and contraindications) and should be tested with smallest amount possible (5mg) , perhaps with the antidote in hand (Benadryl) . Other people have reported severe drowsiness (falling asleep for hours) , and an extremely bizarre feeling -- some describe it "I wanted to run out of my body" (with no other side effects) -- which was enough to make them dump meto and stay away from it. This extremely rare but it is possible . Research first . Otherwise @jgm63 gave the definite answer . There are also alternatives like Domperidone (no EPS at all) and Buccastem .

You should have research all that . So if you're scared or haven't read -- don't do it . Move along .

 

[Goaway]

I have been taking it for 2 days now. Initial side effects have gone away.

 

[br0kenMIND72]

If diphenhydramine helps with meto "worst case scenario" I will buy it, I find it easy to obtain, in my country it will be "Apap noc" with diphenhydramine hydrochloride I guess it's the same thing. I don't want to spread panic or anything, It's just good to be prepared.

 

[Beforeigo]

I was prescribed it years ago and had no side effects to be honest! Sending you love regardless of what decision you choose!

 

[Lastravel]

Most of side effects like akithysia/dyskenisia dissapear once you stop the treatment and are reversible but I understand your fear. Nevertheless you can start with a low dosage and see if you have any trouble with it.

Besides if you ctb, dyskenisia will the last of your worries (humor)

 

[jgm63]

Seriously , comparing pills with direct IV of metoclopramide ?

Let's stop the hysteria.

Meto has risks (and contraindications) and should be tested with smallest amount possible (5mg) , perhaps with the antidote in hand (Benadryl) . Other people have reported severe drowsiness (falling asleep for hours) , and an extremely bizarre feeling -- some describe it "I wanted to run out of my body" (with no other side effects) -- which was enough to make them dump meto and stay away from it. This extremely rare but it is possible . Research first . Otherwise @jgm63 gave the definite answer . There are also alternatives like Domperidone (no EPS at all) and Buccastem .

You should have research all that . So if you're scared or haven't read -- don't do it . Move along .

Thanks professor @Quarky00
Some extra notes....
Diphenhydramine for treating EPS symptoms may be available as Benadryl, or Nytol, or simply as Diphenhydramine, or perhaps as some other product, depending on country. Some products have multiple variants even within the same country. Just ensure the product you buy has Diphenhydramine on the label somewhere.

Note that Buccastem (Prochlorperazine) apparently has a higher EPS risk than meto, so that might not make a good alternative if EPS risk is a concern.

Domperidone has a very low EPS risk, although I'm not 100% certain whether it is as effective as prochlorperazine / metoclopramide.
There are also these points to consider :

Spoiler: Domperidone and SN

https://sanctioned-suicide.net/threads/is-domstal-domperidone-good-enough-for-sn.29445/post-536270

If using Domperidone you would want to leave a 30 minute gap before taking the antacid (that 30 min gap tends to be part of the SN protocol anyhow if following Stan's guide)

 

[AcornUnderground]

I was prescribed Meto 15 years ago for a stomach disorder. I developed tardive dyskensia and severe agitation, as well as a major depressive episode - another risk. However it took prolonged use. Even with my severe reaction to meto I would say that 2-3 days of dosing at pill levels will NOT cause these issues.

 

[jgm63]

I was prescribed Meto 15 years ago for a stomach disorder. I developed tardive dyskensia and severe agitation, as well as a major depressive episode - another risk. However it took prolonged use. Even with my severe reaction to meto I would say that 2-3 days of dosing at pill levels will NOT cause these issues.

To clarify for people who might not read the above post properly (surely not !?), he only got those symptoms after an extended period of using the meto.

 

[AcornUnderground]

To clarify for people who might not read the above post properly (surely not !?), he only got those symptoms after an extended period of using the meto.

Correct! It took MONTHS at 3 x 10 mg a day

 

[Quarky00]

Domperidone has a very low EPS risk, although I'm not 100% certain whether it is as effective as prochlorperazine / metoclopramide.

Domperidone should be as effective as metoclopramide and sometimes better , according to research , however my personal experience is that meto is better . Their D2 receptor affinity is similar . We are not interested in just 'reducing nausea' but preventing serious vomiting (complex stomach brain interaction) and opening those GI valves (sphincters) . All addressed in the FAQ , with alternatives etc :

Can strong effect achieved without Meto?

Ondansetron and Domperidone target peripheral receptors, not the brain (less side effects): Domperidone (Dopamine, less EPS) + Ondansetron (5HT3, less EPS) = Metoclopramide (Dopamine+5HT3 , Brain/EPS)

^ Note that this is example/info only of mode of action and alternatives , not common practice .

 

[seafarer]

I had an issue a few years ago and prescribed me to worked perfectly sickness went away and got no side effects and also a plus I found a steip of them that I hadn't used the other day so I have that covered. But o go early wouldn't be worried about meto. Why are you thinking of the side effects when you are gonna be drinking poison not long after. I have too up to 30mg a day for about 4 weeks and never had any issues from it.

 

[Berlin76]

People on this site are anxious of nature to the extreme.
So conversations like this creates histeria almost.

And the side effects are small and only effects maybe 1in every couple thousand people.

You only need to take it 1 or 2 days one every 8 hours.
Its medication like any other with his side effects. So it wont causes harm

 

[jgm63]

Some people are saying "why worry about EPS if you are CTB-ing", etc.
It's not necessarily quite that simple....

In some *very rare* cases, EPS can be severe and distressing.
For those *very rare* cases, the distress caused or severity of the symptoms could genuinely interfere with someone's ability to go through with an attempt.

So we can't just completely dismiss EPS.
What we need is to try to examine the facts / information available.

> EPS is not very common. Severe EPS is very rare.
> You can test with 5mg of meto, and do further spaced out tests, building up the amount gradually
> You can have diphenhydramine on standby to treat EPS symptoms in the unlikely event that you get them
> Or you could just not worry about it, and for most people that will be okay, but there is a small risk, so ideally it's better to do the tests explained above if you can.

 

[Rdc]

What are the odds of developing eps or experiencing long lasting side effects from a stat dose of 30mg of meto? Would it be better to go through with the 48hour regime of taking 10mg every 8 hours to give your body time to adjust to the medicine before taking the 30mg? Does it really make a difference? The reason I'm concerned about eps is because I know there is a possibility I could end up taking the meto and then having my si and anxiety kick in and not take the SN. I already have severe anxiety and ocd and don't want it to get permanently worse by the meto. I think one of the side effects of meto is restlessness/ increased anxiety. I don't want to worsen my broken mental state with more meds.