i've had times where i've abused it. once you start chasing a particular feeling or headspace and can't put it away, it's time for at the very least a tolerance break. you can communicate your desire to do so to wherever you get it (hopefully they are kind and not just after your money like most) and they might be able to help with advice etc.
for me, if I don't have k, or am taking a break, I smoke a lot more weed. obviously they aren't nearly the same.
but trust me, your body will thank you, whether it's your nose or entire urinary system (k abuse without breaking it down or having enough water while using can cause stones amongst other issues)
edit: I didn't include things like an official detox etc but if you're poly using you may need it. but ket isn't one that will kill or cause seizures (minus certain medical issues or complications) if you just cold turkey when you run out. it's chemical structure is not that of benzos/alcohol/etc. this is not medical advice, it's anecdotal. I am not in medical care.
but be prepared for depression etc flair ups.
if you have ANY urinary issues, it's time to get checked out. hospitals (US) do not care about your drug use, only honesty so they can treat you properly, which most likely would be fluids. definitely mind your water intake friend. you got this. it doesn't have to be forever but a good thing doesn't stay that way if it's constant.