Something worth considering is exercise. Feel free to roll your eyes I don't care. The efficacy of it speaks for itself. Kicks the crap out of most things and you at least won't risk permanent side effects. Want me to dig up peer-reviewed sources I will? Lately, I can't be bothered as rarely does anyone read them anyway.
Same goes for meditation as well especially the variant that uses muscle relaxing techniques. I can't comment on spiritual things.
We are not meant to live sedentary lives living vicariously through screens terrified of the media distortion that live inside our head like an ever-present tiger ready to pounce.
No idea if you sit and stew over things. Have imaginary conversations in your head with people who have slighted you, or ruminate on past events. The thing with brains is they don't truly recognise a memory or imagined event from if something is happening in the now, nightmares don't help either. So you reignite all that stress. All though stress should be renamed brain damage because that is pretty much what it does. There is nothing trivial about chronic anxiety especially if it was renamed ongoing brain damage.
https://www.sciencedaily.com/releases/2016/01/160121121818.htm
So find a method to run from your tiger as a means to trick your brain into thinking you escaped the threat. Literal running has been shown to work well and has a bunch of benefits. You might get to relax for a bit until attacked by your mind again. If though your mind is chronically attacking you then you need to put your focus on what lies beneath and how true it is? You say there is this vague sense of unease, so that makes me wonder if you come from a background of abuse or an unstable upbringing?
Bad news if you come from a background of long term abuse or instability this sense of unease is tough to ever get entirely gone. For the same reason, deer don't just relax when aware of predators, especially if they have been mauled by one.
All you can do is try and analyse what your predators are. Fair to say life, in general, can feel like a predator. If you have been hurt a lot shutting down from that sense is hard. Probably what that constant sense of unease is that can't be resolved. To avoid a predator is to be alert to them in the first place. This likely leaves you aware of every nuance of the behaviour of people around you and your environment, everything gets filtered through a lens of looking for the threat.
Either takes therapy work to undo the ingrained damage. Sadly that requires a competent therapist and the capacity to stare at the predators of the past. My stepfather haunted me a long while after I was out of that situation and I did not truly know it until a breakdown. I benefited from C.A.T because it explored the past and how that fed my anxieties to the point of being crippled by them. I beat that shit and in doing so also figured out how not to give a fuck and for it to be okay to offend and upset people and not be everyone's doormat.
Also maybe the sense of unease is based on a multitude of genuine threats that exist beyond the glow of a screen. Things beyond your capacity to control but can eventually hurt you. Most people naturally shut off from that focused in the now of daily routines. But if you have been mauled by predators it is just another predator ominously lurking making it hard to ignore.
Again it is hard to shut down from that. So you have to force it by doing something that feeds personal passions you can get lost in or vent that pent up feeling through movement. As well as find acceptance in not being able to fix things that are beyond your control in the first place. Then recognise being anxious about these threats does not improve anything. It is just wasted energy. That energy is better spent on what is improvable in your life or has value worth sinking time into. Instead of wishing for a less toxic stupid world full of predators. Because this basically is it. In that acceptance, there is a kind of relief. Well, that is true for me. I have blathered enough.