UNSUCCESSFUL with Antiemetics
drakewantstogo: 17g, stat dose of 30mg metoclopramide, 225mg Zantac, fasted for more than 8 hours, after 5 minutes vomited 3 times, after 15 minutes did not feel drowsy, felt happy and excited at first but then felt anxiety, mild dissociation, blindness, felt bad – pain 6/10, called emergency services, arrived 45 minutes after intake.
Querry1: 15g in 60ml water, stat dose of weak antiemetic, fasted for 6 hours, heart beating fast, vomited after 20 minutes, after 30 minutes felt unbearable pain 6-7/10, called emergency services, blacked out after 1 hour.
ultraviolet sin: 20g drank over an hour, regimen meto, Xanax, no fasting, didn't vomit, didn't hurt, felt euphoric, found by police in hotel room 1 hour 40 minutes after, "out of it" while being treated.
X-Kid: 2 tablespoons in 1.5 cups water, had two sips, 8mg ondansetron afterward, felt fine but burning in nostrils, unconscious after 20 minutes, no pain, roommate found him passed out with blue/grey face and called emergency services, doctors claimed would be dead if not found.
Lotus: 20g, stat dose antiemetic, fasted all day, loss of vision/vision blurred, vomited after 20 minutes then felt no pain, fast heartbeat, passed out, police came into room after last sip as someone had called emergency services.
axorz: 17g, stat dose of meto, benzos, Tagamet, 8 hour fast. Vomited immediately after drinking, lost consciousness after about 10 seconds, brother called ambulance. No long term consequences.
zajebistakaczka: 20g, 48 hour regimen of meto, alprazolam, 2mg Xanax.
SCIENTIFIC ARTICLES (UNSUCCESSFUL)
A 23-year-old female presented to the emergency department after intentionally ingesting an unspecified amount of sodium nitrate. She presented by ambulance to the hospital profoundly cyanotic and unresponsive. The patient's initial methemoglobin level was 92.7%.
A 52-year-old male was transported to hospital after being found at home by family, unconscious and slumped awkwardly for approximately 24 hours. After treatment reported chest pains, kidney injury due to SN, deep vein thrombosis, cognitive impairment (unclear if this was due to past history of ECT or SN).
Sodium nitrite ingestion for suicidal attempt, presented in unconsciousness, shock and deeply cyanosed condition. He was pulseless and had no recordable BP with methemoglobin level of 77%. He completely recovered after two days. Survival in a case of methemoglobinemia with extremely high level of methemoglobin, non-recordable BP and deep cyanosis is rarely reported.
Poisoning with sodium nitrite in three family members after eating homemade sausages given to them by their neighbour who was a butcher. The concentration of sodium nitrite in the homemade sausages was about 3.5g per 1kg of meat, almost 30 times higher than allowed according to legislation. A 70-year-old man died about 7 hours after consuming the meal, while two women, 53 and 67 years of age, respectively, were admitted to a toxicology clinic the following day due to food poisoning, with the maximum concentration of MHb in blood of 33.7 and 20.4%, respectively. They were discharged 3 days later. The autopsy of the deceased man showed sodium nitrite poisoning with a relatively low concentration of MHb in his blood – 9.87%. Death was attributed to the exacerbation of hypertensive and ischemic heart disease, resulting from accidental sodium nitrite poisoning.
11 men, aged 60 to 80, had been admitted to hospital with cyanosis and shock. In each instance illness occurred within 5 to 30 minutes after eating breakfast. They became dizzy, felt weak, and complained of abdominal cramps. Eight of them vomited and all had diarrhoea. Five of them became unconscious shortly after onset of symptoms. They had subnormal temperatures, cold extremities, and low blood pressures. In addition, all had cyanosis. All but one patient recovered. This man, age 82, died the following morning. Autopsy revealed bronchopneumonia. The only other abnormal finding was a diffuse mahogany brown discoloration of the organs.
A 28-year-old man was brought to our emergency department because of transient loss of consciousness and cyanosis. He was immediately intubated and ventilated with 100% oxygen. A blood test revealed a methemoglobin level of 92.5%.
Outcome. We treated the patient with gastric lavage, activated charcoal, and methylene blue (2 mg/kg) administered intravenously. Soon after receiving methylene blue, his cyanosis resolved and the methemoglobin level began to decrease. After relocation to the intensive care unit, his consciousness improved and he could recall ingesting approximately 15 g sodium nitrite about 1 hour before he was brought to our hospital. The patient was discharged on day 7 without neurologic impairment.
A woman in her 20s was brought to the casualty clinic due to symptoms of psychosis, and it was deemed necessary to section her. While she was there, she drank two small bottles of reagents that she found in a Strep test kit. She then became somnolent and her oxygen saturation decreased. Guidance from the Poisons Information Centre was required for rapid clarification and correct treatment.
We present two patients who were treated for an intentional overdose of sodium nitrite. When ingested sodium nitrite leads to severe methaemoglobinaemia, resulting in severe hypoxia (as methaemoglobin does not transport oxygen), vasodilation and hypotension. Symptoms include cyanosis, headache, nausea, convulsions, coma and death. When measured by pulse oximetry, patients with a sodium nitrite intoxication and severe methaemoglobinaemia generally have an oxygen saturation of around 85%. This value is unreliable as the oxygen content of the blood is often extremely low - this can be confirmed by arterial blood gas analysis. Treatment of sodium nitrite intoxication consists of intravenous administration of methylthioninium chloride 1-2 mg/kg. Methylthioninium chloride converts the methaemoglobin back to haemoglobin.
A
20-year-old man presented to the ED after intentional ingestion of 750 mg of powdered sodium nitrite(98% by weight). He had been experiencing major depressive disorder for the last 6 months but had not taken medicine recently. He was under stress from a college issue and felt pressured to succeed in the future. He remained depressed for most of the day and repeatedly thought of death. He prepared a pill by filling an empty pill capsule with sodium nitrite powder and taking it with water at home. One hour later, the patient visited the ED. He stated that he obtained information on how to make the suicide pill from an online suicide forum and purchased sodium nitrite online. He brought a bottle containing 500 grams of 98% sodium nitrite by weight that he purchased online (Fig. 3). He experienced only mild nausea a few minutes after ingesting a self-produced suicide pill. A physical examination revealed no signs of central or peripheral cyanosis, and the patient was hemodynamically stable. The initial methemoglobin level was 4.8. His methemoglobin level returned to normal 2 hours after ingestion. Methemoglobin levels did not change following repeated measurements. The patient recovered without any problems with conservative supportive treatment.
This person used low purity sodium nitrite, A
23-year-old male with a medical history significant for previous suicide attempts, polysubstance use disorder in remission from alcohol and benzodiazepine use, nicotine dependence, current marijuana use, bipolar disorder, post-traumatic stress disorder, and irritable bowel syndrome presented to the emergency department via emergency medical services (EMS) after intentional overdose. Patient reported ingesting 2 teaspoons of sodium nitrite he obtained from Walmart.com 6 hours before presentation in an attempt to end his life.The patient reported losing consciousness after ingestion and waking up in his own vomit and feces. He felt confused and called EMS. In the emergency department (ED), the patient acknowledged nausea, vomiting, and bowel incontinence. He complained of severe diffuse abdominal pain that was 8/10 in severity. He had used marijuana that day. He denied chest pain, shortness of breath, coingestion with other prescription drugs, over-the-counter drugs, street drugs, and ethanol. He had no auditory hallucinations, current suicidal ideation, or current homicidal ideation. Patient was released with no damage.
Credits to
@hadenough
SN Success rate 83%. Less than 20% reported pain
Background: Over the years, forensic pathology has registered the spread of new methods of suicide, such as the ingestion of sodium nitrite. Sodium nitrite causes increased methemoglobin, resulting in systemic hypoxia, metabolic acidosis, and cyanosis. Since sodium nitrite is a preservative, the...
www.mdpi.com
44/53 of those that took it on purpose died (89% of men died, 67% of women, but the sample size for women was smaller)
Even 57% of those that were hospitalized died
In 95 cases, it was possible to collect information relating to the symptoms (Figure 3). The symptoms that were most commonly presented were cyanosis of the face and/or extremities (64; 48.49%), breathing abnormalities (64; 48.49%), altered level of consciousness (57; 43.18%), dizziness (30; 22.73%), vomiting (28; 21.21%), nausea (22; 16.67%), pain (headache: 18, 13.64%; abdominal pain: 1, 0.76%, and chest pain: 1, 0.76%), and tachycardia (19; 14.39%).
Credits to
@neonlol and his thread
https://www.mdpi.com/1660-4601/19/21/13996 44/53 of those that took it on purpose died (89% of men died, 67% of women, but the sample size for women was smaller) Even 57% of those that were hospitalized died In 95 cases, it was possible to collect information relating to the symptoms (Figure...
sanctioned-suicide.net
