DDMP

[MG_39]

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Topic preface: Whenever I start a topic here I'm going to start with this, and I hope it's okay. Why? because I see both the good and the bad things with this forum.
The good thing is that you can avoid mistakes which could result in worse conditions than you where in before your ctb, the bad thing is that someone can make a bad decision for a temporary problem.
If you read this and something recently happened in your life, and you feel like you don't want to live anymore, and nothing can change that. Then remember even though it's hard right now, things change in life, and a lot of us have been there. I'm middle age (around 50yo) I have been there two times in my life. It was so painful, and I was sure my life was destroyed. I choose to talk to someone, and since then I've had a lot of happy moments in my life. If you have struggled for a very long time and see no other way, have you really tried everything? could a last solution be to sell everything and travel? or do other radical changes in your life, since you have nothing too loose? Please try EVERYTHING before you make this decision.
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I have a few questions regarding DDMP (4 Drug protocol)

500mg Diazepam
25mg Digoxin
2gm Propranolol
10gm Morphine sulphate

Questions:
* I don't get the amount of morphine here, I read somewhere that LD50 is around 200mg.

* Does it have to be Morphine or would for example Oxycontin work?

 

[allgood]

Depends which opiates, oxy would work for sure but something like codeine probably wouldn't be advisable. The dose of M is high probably either because it is given orally (M has a low oral bioavailability) and/or because DDMP has to be certain due to it being used for executions(?); I'm sure you could get away with anywhere between 2-5g, as a conservative estimate, if you were to use this method yourself.

DDMP II actually suggests up to 15g morphine but I suspect it really is down to the application of this cocktail.

 

[MG_39]

Depends which opiates, oxy would work for sure but something like codeine probably wouldn't be advisable. The dose of M is high probably either because it is given orally (M has an extraordinarily low oral bioavailability) and/or because DDMP has to be certain due to it being used for executions(?); I'm sure you could get away with anywhere between 2-5g, as a conservative estimate, if you were to use this method yourself.

Thank you for your answer. I also have to be certain. Exit bag with inert gas seems peaceful, but worried something would go wrong. That's the reason i'm looking into DDMP.

 

[allgood]

Thank you for your answer. I also have to be certain. Exit bag with inert gas seems peaceful, but worried something would go wrong. That's the reason i'm looking into DDMP.

I've read a bit into DDMP/DDMP2 and it does seem to be a very reliable method, with that mix of drugs I don't think you can really go wrong. Lesser amounts of morphine would be fine IMO, 10g of M is quite difficult for most to acquire. Personally I wouldn't want to risk going lower than 4g orally with a .25 BA.

 

[MG_39]

I've read a bit into DDMP/DDMP2 and it does seem to be a very reliable method, with that mix of drugs I don't think you can really go wrong. Lesser amounts of morphine would be fine IMO, 10g of M is quite difficult for most to acquire. Personally I wouldn't want to risk going lower than 4g orally with a .25 BA.

I have seen 3-drug protocol and DDMP, what is DDMP2?

Also, how about the risk of throwing up? I'm worried about taking metoclopramide, because side effects of medicine always seems to affect me hard.

 

[pane]

Aren't all the drugs used in the DDMP2 protocol prescription-only though?

 

[DetachedDreamer97]

Aren't all the drugs used in the DDMP2 protocol prescription-only though?

Yeah, however... it's not like we couldn't improvise.

 

[MG_39]

Aren't all the drugs used in the DDMP2 protocol prescription-only though?

In Europe there are sources to buy most prescription drugs, and i guess you can in Us too, or wherever you live.

 

[pane]

Yeah, however... it's not like we couldn't improvise.

Nixonnate could you please explain how we might improvise the DDMP2 protocol?

 

[allgood]

Nixonnate could you please explain how we might improvise the DDMP2 protocol?

The only drug there that is really any trouble to get is Digoxin, diazepam is available UK wide on the street and DNMs, and could be substituted with any other benzo. Morphine sulphate is difficult to source and expensive but could be replaced by oral heroin (metabolises into morphine) or other similar opiate/synthetic such as acetylfentanyl. Propanolol is a very commonly prescribed drug, though despite this it's not really sold on the street as it's not recreational, last I checked it's available on DNMs but you could probably be scripted it from a GP very easily and stockpile provided you can convince them you're displaying physical symptoms of anxiety.

Even without Digoxin this cocktail would work perfectly fine, obviously with appropriate anti-emetics. Unless you are immediately narcanned I see no way for you to survive 10g+ morphine with the other drugs.

 

[DetachedDreamer97]

Nixonnate could you please explain how we might improvise the DDMP2 protocol?

Well... I made a thing called the NYAN cocktail. But that's changed after I read some posts about loperamide among other things.

Digoxin could be substituted with Cerberin.
Morphine would be substituted with loperamide, however being that we need a p-glycoprotein inhibitor (without a prescription), theobromine would suffice, as it is effective at that. Perhaps 500mg. Available in chocolate or as an extract.
2methyl2butanol will work in place of diazepam.
For propranolol, akuamma would be good for that.

 

[allgood]

Well... I made a thing called the NYAN cocktail. But that's changed after I read some posts about loperamide among other things.

Digoxin could be substituted with Cerberin.
Morphine would be substituted with loperamide, however being that we need a p-glycoprotein inhibitor (without a prescription), theobromine would suffice, as it is effective at that. Perhaps 500mg. Available in chocolate or as an extract.
2methyl2butanol will work in place of diazepam.
For propranolol, akuamma would be good for that.

Why even bother substituting such drugs though, cerberin makes sense but the others? Does akuammine even have any effect at all? Loperamide with a
P-glycoprotein inhibitor was probably thought to cause respiratory depression + increased chance of opiate toxicity but it really doesn't, and given that loperamide has at best a weak effect on CNS I don't see how this is in any way a substitute for morphine which could be bought by anyone with a couple day's research.

 

[DetachedDreamer97]

Why even bother substituting such drugs though, cerberin makes sense but the others? Does akuammine even have any effect at all?

Yep. One of its effects are hypotension. With other benefits. Such as blocking pain as well as being anti-diarrheal.

 

[allgood]

Yep. One of its effects are hypotension. With other benefits. Such as blocking pain as well as being anti-diarrheal.

Yeh I think I'd rather stick with propanolol. The interaction between propanolol and cardiac glycosides is well studied and pretty certain to cause severe cardiac toxicity, whereas akuamma's hypotensive properties are barely even listed on google; in fact I can't find any research at all regarding how effective it is for that purpose. Maybe you do? Genuinely quite interested at this point, good to know that it's an opioid antagonist.

 

[calendulo]

About mixtures I was long time studying 3 drug protocol. Phenob + Hydrt Chloral + Morphine. Have enough literature about.
DDMP is in the guide, digoxin instead anesthesyc, raise up morphine and remove barbiturate and add a benzo diazepam.

Have to swallow that.

IMHO, would do the 3 drug protocol. It is proof and tested.

 

[allgood]

About mixtures I was long time studying 3 drug protocol. Phenob + Hydrt Chloral + Morphine. Have enough literature about.
DDMP is in the guide, digoxin instead anesthesyc, raise up morphine and remove barbiturate and add a benzo diazepam.

Have to swallow that.

IMHO, would do the 3 drug protocol. It is proof and tested.

AFAIK phenobarbital was 'replaced' because elderly patients were experiencing discomfort from the taste, or at least this was part of it.

 

[calendulo]

AFAIK phenobarbital was 'replaced' because elderly patients were experiencing discomfort from the taste, or at least this was part of it.

I read nothing about DDMF, but guess changing phenobarbital by digoxin only can to be why you can not to get a barbiturate.

The former 3drug protocol had pentobarbital, but lately it was changed by pheno because pentobarbital raised up of price. Availability issues guess.

 

[DetachedDreamer97]

Yeh I think I'd rather stick with propanolol. The interaction between propanolol and cardiac glycosides is well studied and pretty certain to cause severe cardiac toxicity, whereas akuamma's hypotensive properties are barely even listed on google; in fact I can't find any research at all regarding how effective it is for that purpose. Maybe you do? Genuinely quite interested at this point, good to know that it's an opioid antagonist.

Yeah, I agree it was difficult to find. But I found it when I was broke and researching alternatives for these drugs. Heres a few things I got.

Protabase Record

https://www.researchgate.net/publication/259719376_Medicinal_uses_phytochemistry_and_pharmacology_of_Picralima_nitida_Apocynaceae_in_tropical_diseases_A_review

https://www.researchgate.net/profile/Osayemwenre_Erharuyi/publication/259719376_Medicinal_uses_phytochemistry_and_pharmacology_of_Picralima_nitida_Apocynaceae_in_tropical_diseases_A_review/links/55b772b108aec0e5f4381d2d/Medicinal-uses-phytochemistry-and-pharmacology-of-Picralima-nitida-Apocynaceae-in-tropical-diseases-A-review.pdf?origin=publication_detail

And here's this to explore deeper.

LMGTFY - Let Me Google That For You

For all those people who find it more convenient to bother you with their question rather than to Google it for themselves.

lmgtfy.com

 

[MG_39]

A couple of thoughts after reading this post https://sanctioned-suicide.net/threads/drug-overdose-thread.4186/#post-61229

Since the drug cocktail was is used for people close to death and often people with cancer who have a higher tolerance of morphine already, I would say someone like me without tolerance can use 5gm morphine with guaranteed results. I mean a just morphine alone around 2-300mg can be deadly for me.

But there is one thing I can't understand regarding "With the new protocol, patients passed more quickly, and there were no adverse events other than the nausea and vomiting often seen in terminally ill patients. "

Does this mean it doesn't matter if you throw up? maybe someone can explain this? when is the biggest risk to throw up, right after you ingest the drug or when the drugs start to act? if it's the later it seems like DDMP is actually a better choice than liquid N, both because you probably won't need anti-emetics and it's a lot easier to source.

 

[allgood]

I assume vomiting barely matters because the entire cocktail is IV? They are probably still using anti-emetics. 5g morphine is probably fine, roughly equivalent to about a gram or so if taken orally which certainly meets the requirements.

 

[MG_39]

I assume vomiting barely matters because the entire cocktail is IV? They are probably still using anti-emetics. 5g morphine is probably fine, roughly equivalent to about a gram or so if taken orally which certainly meets the requirements.

It seems like this is used oral from the medscape article
"In these states, the law allows physicians to offer terminally ill adults the option of a lethal dose of an oral prescription medication, provided the patient meets strict criteria."

 

[allgood]

I mean past a certain point yeh vomiting isn't going to do much, I assume it happens after about 30 minutes. Even then I don't see why it'd be worth dropping anti-emetics considering they're not exactly hard to source at the moment.

 

[setmefree]

----------------------------------------------------------------------------------------------------------------------------
Topic preface: Whenever I start a topic here I'm going to start with this, and I hope it's okay. Why? because I see both the good and the bad things with this forum.
The good thing is that you can avoid mistakes which could result in worse conditions than you where in before your ctb, the bad thing is that someone can make a bad decision for a temporary problem.
If you read this and something recently happened in your life, and you feel like you don't want to live anymore, and nothing can change that. Then remember even though it's hard right now, things change in life, and a lot of us have been there. I'm middle age (around 50yo) I have been there two times in my life. It was so painful, and I was sure my life was destroyed. I choose to talk to someone, and since then I've had a lot of happy moments in my life. If you have struggled for a very long time and see no other way, have you really tried everything? could a last solution be to sell everything and travel? or do other radical changes in your life, since you have nothing too loose? Please try EVERYTHING before you make this decision.
-----------------------------------------------------------------------------------------------------------------------------

I have a few questions regarding DDMP (4 Drug protocol)

500mg Diazepam
25mg Digoxin
2gm Propranolol
10gm Morphine sulphate

Questions:
* I don't get the amount of morphine here, I read somewhere that LD50 is around 200mg.

* Does it have to be Morphine or would for example Oxycontin work?

Hi I have a question about that.. are you still here??