D
Difficult life
Member
- Dec 9, 2018
- 11
Does carfentanyl overdose lead lo peaceful death in ppeh it is said it bring peaceful death
Yes. 100 times more potent than Fentanyl. As peaceful as you can get. Not easy to find, I'm guessing.Does carfentanyl overdose lead lo peaceful death in ppeh it is said it bring peaceful death
So. Comfortably numb for sure, but watch that dosing!From Wiki:
"Carfentanil has been sold since 1986 under the brand name "Wildnil" for use in tranquilizer darts in combination with an α2-adrenoreceptor agonist for large mammals including elk and elephants. It is chosen for its high safety margin as the fatal dose of carfentanil is approximately the same as that of fentanyl despite much higher opioid activity."
So expect to feel a lot better, but still need the same amount to ctb. In fact, later on the page it notes:
"It is important to note that lethality and potency are not the same, and carfentanil is less fatal than fentanyl in rats."
I'd be interested in more sources for this, I've read that carfentanyl is a LOT stronger than fent and also get the feeling there haven't been enough carfentanyl deaths for there to be real statistics on this. Your statement is about how it affects elephants and stuff, I'm not sure you can guarantee the same effect for humans.From Wiki:
"Carfentanil has been sold since 1986 under the brand name "Wildnil" for use in tranquilizer darts in combination with an α2-adrenoreceptor agonist for large mammals including elk and elephants. It is chosen for its high safety margin as the fatal dose of carfentanil is approximately the same as that of fentanyl despite much higher opioid activity."
So expect to feel a lot better, but still need the same amount to ctb. In fact, later on the page it notes:
"It is important to note that lethality and potency are not the same, and carfentanil is less fatal than fentanyl in rats."
It's very interesting, but I think for our purposes it's only theoretical, since it's probably easier to get your hands on weapons-grade plutonium.I'd be interested in more sources for this, I've read that carfentanyl is a LOT stronger than fent and also get the feeling there haven't been enough carfentanyl deaths for there to be real statistics on this. Your statement is about how it affects elephants and stuff, I'm not sure you can guarantee the same effect for humans.
Exactly, and if you could get hold of any amount of carfentanyl, it'd probably be enough to kill you lol I'm just being contrary for the sake of itIt's very interesting, but I think for our purposes it's only theoretical, since it's probably easier to get your hands on weapons-grade plutonium.
Hang on, I'm researching death by plutonium radiation poisoning...Exactly, and if you could get hold of any amount of carfentanyl, it'd probably be enough to kill you lol I'm just being contrary for the sake of it
The analgesic efficacy of carfentanyl is much greater than that of fentanyl --"For pain relief, a unit of carfentanil is 100 times as potent as the same amount of fentanyl, 5,000 times as potent as a unit of heroin and 10,000 times as potent as a unit of morphine."-- but it has a lower lethality. So yes, it is stronger, just not stronger in the characteristics we here at ss would value.I'd be interested in more sources for this, I've read that carfentanyl is a LOT stronger than fent and also get the feeling there haven't been enough carfentanyl deaths for there to be real statistics on this. Your statement is about how it affects elephants and stuff, I'm not sure you can guarantee the same effect for humans.
but when they say the effect is like that, they say it with observational evidence rather than some chemical or molecular proof right? that's why we have to assume things can behave differently in other animals. Like when we test dosages on mice and rats it's only an indicator. Interesting though I didn't know that about the hostage crisis.The analgesic efficacy of carfentanyl is much greater than that of fentanyl --"For pain relief, a unit of carfentanil is 100 times as potent as the same amount of fentanyl, 5,000 times as potent as a unit of heroin and 10,000 times as potent as a unit of morphine."-- but it has a lower lethality. So yes, it is stronger, just not stronger in the characteristics we here at ss would value.
As for deaths, it sounds like at least 125 of the dead in the Moscow Theater hostage crisis were killed by aerosolized carfentanyl pumped in to knock out the terrorists --after which, the rescuers didn't have enough narcan on hand to save the hostages. (Nice planning, guys!) Hardly a well structured experiment, but worth noting.
However, I agree --with some sorrow-- that its severely restricted availability makes discussion of its use as a peaceful exit completely moot.
Given that carfentanyl was first synthesized in 1974, I suspect it has a long and well established history of theraputic medical use, with all the lab testing --molecular and animal tests-- to back up those assertions of efficacy. So yes, animal testing is only a very general assessment of how it might effect humans, but in those 44 years I suspect there has been adequate empirical observation in human subjects to have a very solid basis for the assertions of efficacy.but when they say the effect is like that, they say it with observational evidence rather than some chemical or molecular proof right? that's why we have to assume things can behave differently in other animals. Like when we test dosages on mice and rats it's only an indicator. Interesting though I didn't know that about the hostage crisis.
Suspecting something backs up your claim doesn't really count for much... Really all I'm refuting is that carfent isn't more deadly than fent, the source that statement in the wiki is referring to doesn't even seem to say regarding the letahl dose being similar... There have been a few studies on fentanyl and less so on carfent but details on the fatal dose in humans are simply not known. You're right there is something to suggest it's a possibility it may not be as potent in humans as expected, yet being a drug that's classically known as 100 times stronger than fentanyl and not intended for use in humans... which no real data on toxicity in humans, I don't think it's wise to assume that carfent might be as "safe" as fentanyl. It won't affect 99.99% of people who ever come on this site but still.Given that carfentanyl was first synthesized in 1974, I suspect it has a long and well established history of theraputic medical use, with all the lab testing --molecular and animal tests-- to back up those assertions of efficacy. So yes, animal testing is only a very general assessment of how it might effect humans, but in those 44 years I suspect there has been adequate empirical observation in human subjects to have a very solid basis for the assertions of efficacy.
There's also the complicating factor that opioids have wildly varying reactions in different humans. A friend of mine gets zero analgesic effect from opioids, up to and including morphine --and having bashed herself up in equestrian events she has plenty of experience with painkillers-- but they make her hysterically sad. So there she is in the ambulace, sobbing uncontrollably, unable to express the problem, and with no pain relief. (Keep this in mind, anyone reading this who is considering ctb with opioids!) Opioids are very much a case study for "your mileage might vary." This makes any assertion of efficacy challenging on an individual basis, but for broad-brush statements I suspect it all averages out across a large experimental population.
EMCDDA (2015): "[While] carfentanil is said to be 10,000 times more potent than
morphine, it is difficult to be certain that this incr
eased analgesic potency means that the
euphoric effects are similarly increased, and more importantly, whether the overdose
potential of these analogues is also increased by the same margin".
Swanson et al. (2017) noted:
"While there are no known publications on carfentanil
human toxicity, expected symptoms are consistent with opioid toxicity which
includes sedation, dizziness and
[potentially life-threatening]
respiratory depression. Naloxone can reverse these effects although several doses of naloxone may be required due to the unusually high potency of carfentanil (DEA, 2016; Lust et al., 2011)."
Fair enough. I'm not so invested in the subject I intend to go do more research for splitting hairs --especially when it's such an academic point. I'd be happy to get my hands on either as an agent by which I might ctb, but since I can't see any avenue by which to acquire either one, trying to sort out comparatively how much of either I would need seems a silly diversion.Suspecting something backs up your claim doesn't really count for much... Really all I'm refuting is that carfent isn't more deadly than fent, the source that statement in the wiki is referring to doesn't even seem to say regarding the letahl dose being similar... There have been a few studies on fentanyl and less so on carfent but details on the fatal dose in humans are simply not known. You're right there is something to suggest it's a possibility it may not be as potent in humans as expected, yet being a drug that's classically known as 100 times stronger than fentanyl and not intended for use in humans... which no real data on toxicity in humans, I don't think it's wise to assume that carfent might be as "safe" as fentanyl. It won't affect 99.99% of people who ever come on this site but still.
Fair enough. I'm not so invested in the subject I intend to go do more research for splitting hairs --especially when it's such an academic point. I'd be happy to get my hands on either as an agent by which I might ctb, but since I can't see any avenue by which to acquire either one, trying to sort out comparatively how much of either I would need seems a silly diversion.
Here's a question, though, showing how ignorant I am of opioids: I have a strong aversion to needles; would fentanyl be effective orally, and if so, how would an oral dose differ in size from an injected dose? In my fentanyl fantasy I use transdermal patches, but supposing I were to come across a source of fentanyl powder, would I be able to load it into a gelatine capsule and swallow it? Again, a largely academic question since I am unlikely to acquire the stuff, but I'm curious.