Yes, it is possible to die from an overdose of venlafaxine! Cases are described in the literature!
I read so often that antidepressants are not fatal. I find this statement extremely dangerous. There are quite a few people who plan or desire an appelative suicide attempt. But hardly anyone would ever admit that. I don't find that reprehensible either, the pressure of suffering is still extremely high, otherwise people wouldn't do it. And to say to such people, no problem, you don't die from an overdose of antidepressants.... That scares me. Tricyclic antidepressants in particular are quickly fatal. But SSRIs or SNRIs (= venlafaxine) can also be fatal. But it is probably a really serious death, because symptoms can be, for example, heart palpitations, seizures, cardiac arrhythmias.
I don't mean my answer to say that the OP is planning an attempt that she would like to survive!!! But there are so many others reading along here. Whose story and age you don't know. I was in a psychiatric ward for 2 years as a teenager. No one seriously (!!) wanted to die then. But there were always attempts. And yes, I was pro-choice even as a teenager, but you have to be very careful with the statement that you can't kill yourself with it.
Sorry for mistakes, I used a translator.
Much love,
Regen