I seemed to have developed a strong natural tolerance towards serotonergic psychedelics after an overdose on SSRI:s.
Ketamine I've had some pleasurable experiences on though, never even closed to k-holed though. Once saw a brief glance of "god", Also it really made me religiously convicted for a the time I was on it, Feelt and though of religion in a way I never had. I'm an extremely nonreligious person when sober. I also dissociated from myself and could observe myself, what I was doing in my life at that current time, and reflect over who I am as an outside observer.