my psych just prescribed me mirtazapine for weight gain/depression! i haven't started it yet but ill post back here after a few weeks once i have more experience with it. i do wanna say though, although i'm no biologist, i know that most/all psychiatric medications, especially more modern ones like mirtazapine, are specifically formulated not to be lethal at high doses. i also read a reddit post from a guy who took 300mg of it along with some benzos/alc and only ended up feeling like shit the next day, so i highly doubt trying to OD on it would land you with anything more than a traumatic trip to the ER and possibly the ward.