Alternative antiemetics?

[anxiousguineapig]

Why is metoclopramide specifically the main antiemetic that is used/discussed for using with SN? I don't have any good way of getting it, but I do have ondansetron (Zofran) which is a different prescription antiemetic. And of course anything available without a prescription.

Is meto more effective? Is there a reason nobody uses zofran instead?

 

[Doombox]

As I understand it the key to meto is that it speeds gastric emptying, while ondansetron does not. I myself was wondering about ginger because it apparently speeds gastric emptying.

 

[befree]

I don´t see a reason not to use Zofran. https://www.drugs.com/zofran.html
You can also use Domperidone or Diphenhydramin(chlorid).

 

[mykitsune]

What about olanzipine

 

[befree]

Olanzipine is not an antiemetic.

Olanzapine 10 mg tablets - Summary of Product Characteristics (SmPC) - (emc)

Olanzapine 10 mg tablets - Summary of Product Characteristics (SmPC) by Aurobindo Pharma - Milpharm Ltd.

www.medicines.org.uk

 

[PoorFarmer]

• Antiemetic

The second most important step of the method after making the SN drink and swallowing it, is for the SN to stay in your stomach. You are drinking a toxic liquid and your body defences will recognise this and may try to cleanse your body. One of the defence systems is vomiting.

Below is a list of antiemtics in their generic name. Some countries may have a brand name for these drugs:

1. Domperidone
2. Metoclopramide
3. Olanzapine
4. Alizapramide
5. Chlorpromazine
6. Prochlorperazine

You only need access to one of the above

Some of you may be on antipsychotics as part of your mental health treatment. If you are any of the below, there is no need to take any antiemetic as they already function as an antiemetic.


Droperidol- 0,25 nM. Benperidol- 0,027 nM. Trifuperidol- 0,4 nM. Spiperone- 0,053 nM. Haloperidol- 2,0. Bromperidol- 2,1. Lurasidone- 1,0 nM. Sestindole- 2,7 nM. Paliperidone- 2,8 nM. Risperidone- 4,9 nM. Olanzapine- 21 nM. Clozapine- 144 nM. Quetiapine- 245 nM


this is from stans guide, any of these should do the job

 

[deathissosad]

do you guys think Domperidone alone is good instead of pairing it with zofran?

 

[gomenasai]

do you guys think Domperidone alone is good instead of pairing it with zofran?

I think it's a good choice to use domperidone alone since it's also a dopamine antagonist that promotes gastric emptying (which we want).

 

[deathissosad]

Perfect! One less thing to have to source!

I think it's a good choice to use domperidone alone since it's also a dopamine antagonist that promotes gastric emptying (which we want).